CL2019002847A1 - Métodos y composiciones para tratar deficiencias asociadas al envejecimiento utilizando inhibidores de ccr3. - Google Patents

Métodos y composiciones para tratar deficiencias asociadas al envejecimiento utilizando inhibidores de ccr3.

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Publication number
CL2019002847A1
CL2019002847A1 CL2019002847A CL2019002847A CL2019002847A1 CL 2019002847 A1 CL2019002847 A1 CL 2019002847A1 CL 2019002847 A CL2019002847 A CL 2019002847A CL 2019002847 A CL2019002847 A CL 2019002847A CL 2019002847 A1 CL2019002847 A1 CL 2019002847A1
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CL
Chile
Prior art keywords
methods
disease
aging
compositions
cognitive
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Application number
CL2019002847A
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English (en)
Inventor
Karoly Nikolich
S Sakura Minami
Steven P Braithwaite
Original Assignee
Alkahest Inc
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Publication date
Application filed by Alkahest Inc filed Critical Alkahest Inc
Publication of CL2019002847A1 publication Critical patent/CL2019002847A1/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Psychology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A MÉTODO PARA MEJORAR ENFERMEDADES NEURODEGENERATIVAS CON AGENTES MODULADORES DE CCR3. LOS MÉTODOS INCLUYEN ADMINISTRAR UNA CANTIDAD TERAPÉUTICAMENTE EFECTIVA DEL AGENTE MODULADOR DE CCR3 AL SUJETO, CON UNA MEJORA CONCOMITANTE EN LA FUNCIÓN COGNITIVA, MOTORA U OTRA FUNCIÓN AFECTADA DE MANERA NEURODEGENERATIVA. LAS ENFERMEDADES COGNITIVAS Y MOTORAS EN LAS QUE LOS MÉTODOS DE LA INVENCIÓN PUEDEN MEJORAR LA COGNICIÓN INCLUYEN LA ENFERMEDAD DE ALZHEIMER, ENFERMEDAD DE PARKINSON, DEMENCIA FRONTOTEMPORAL, ENFERMEDAD DE HUNTINGTON, ESCLEROSIS LATERAL AMIOTRÓFICA, ESCLEROSIS MÚLTIPLE, GLAUCOMA, DISTROFIA MIOTÓNICA, DEMENCIA VASCULAR, PARÁLISIS SUPRANUCLEAR PROGRESIVA.
CL2019002847A 2017-04-05 2019-10-04 Métodos y composiciones para tratar deficiencias asociadas al envejecimiento utilizando inhibidores de ccr3. CL2019002847A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762482137P 2017-04-05 2017-04-05
US201762560940P 2017-09-20 2017-09-20
US201862620921P 2018-01-23 2018-01-23

Publications (1)

Publication Number Publication Date
CL2019002847A1 true CL2019002847A1 (es) 2020-02-14

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ID=63713276

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CL2019002847A CL2019002847A1 (es) 2017-04-05 2019-10-04 Métodos y composiciones para tratar deficiencias asociadas al envejecimiento utilizando inhibidores de ccr3.

Country Status (15)

Country Link
US (1) US11382907B2 (es)
EP (1) EP3606525A4 (es)
JP (1) JP2020513005A (es)
KR (1) KR20190131078A (es)
CN (1) CN110636844A (es)
AU (2) AU2018250214B2 (es)
BR (1) BR112019020798A2 (es)
CA (1) CA3058967A1 (es)
CL (1) CL2019002847A1 (es)
CO (1) CO2019012164A2 (es)
IL (1) IL269787B (es)
MX (1) MX2019011988A (es)
SG (1) SG11201909245PA (es)
TW (1) TWI791507B (es)
WO (1) WO2018187503A1 (es)

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KR20190131078A (ko) 2017-04-05 2019-11-25 알카헤스트 인코포레이티드 Ccr3-억제제를 사용한 노화 관련 장애 치료를 위한 방법 및 조성물

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US11590118B2 (en) 2017-04-05 2023-02-28 Alkahest Inc. Methods and compositions for treating retina-associated disease using CCR3-inhibitors
US11951102B2 (en) 2017-04-05 2024-04-09 Alkahest Inc. Methods and compositions for treating retina-associated disease using CCR3-inhibitors

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