CL2018002641A1 - Método de producción para derivados de fenoxietanol - Google Patents
Método de producción para derivados de fenoxietanolInfo
- Publication number
- CL2018002641A1 CL2018002641A1 CL2018002641A CL2018002641A CL2018002641A1 CL 2018002641 A1 CL2018002641 A1 CL 2018002641A1 CL 2018002641 A CL2018002641 A CL 2018002641A CL 2018002641 A CL2018002641 A CL 2018002641A CL 2018002641 A1 CL2018002641 A1 CL 2018002641A1
- Authority
- CL
- Chile
- Prior art keywords
- production method
- phenoxyethanol
- formula
- derivatives
- phenoxyethanol derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/46—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PROPORCIONA UN MÉTODO PARA PRODUCIR UN DERIVADO DE FENOXIETANOL. ESTE MÉTODO PARA PRODUCIR UN COMPUESTO REPRESENTADO POR LA FÓRMULA (II) SE CARACTERIZA PORQUE UN COMPUESTO REPRESENTADO POR LA FÓRMULA (I) (EN LA FÓRMULA, R1 ES UN ALQUILO SUSTITUIDO O NO SUSTITUIDO) SE REDUCE EN PRESENCIA DE BOROHIDRURO DE LITIO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016050604 | 2016-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2018002641A1 true CL2018002641A1 (es) | 2019-01-18 |
Family
ID=59851930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2018002641A CL2018002641A1 (es) | 2016-03-15 | 2018-09-14 | Método de producción para derivados de fenoxietanol |
Country Status (14)
Country | Link |
---|---|
US (1) | US10472312B2 (es) |
EP (2) | EP3835285A1 (es) |
JP (1) | JPWO2017159669A1 (es) |
KR (1) | KR102377433B1 (es) |
CN (1) | CN108137457B (es) |
AU (1) | AU2017232476B2 (es) |
BR (1) | BR112018017117B1 (es) |
CA (1) | CA3016545A1 (es) |
CL (1) | CL2018002641A1 (es) |
CO (1) | CO2018009436A2 (es) |
EA (1) | EA039048B1 (es) |
HK (1) | HK1256626A1 (es) |
MX (1) | MX2018010466A (es) |
WO (1) | WO2017159669A1 (es) |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4839639B1 (es) * | 1963-04-15 | 1973-11-26 | ||
FR2162692A5 (es) * | 1971-09-09 | 1973-07-20 | Rhone Poulenc Sa | |
BE788612A (fr) | 1971-09-09 | 1973-03-08 | Rhone Poulenc Sa | Nouveaux herbicides |
DE3512179A1 (de) | 1985-04-03 | 1986-12-04 | Merck Patent Gmbh, 6100 Darmstadt | Fotoinitiatoren fuer die fotopolymerisation in waessrigen systemen |
US4982016A (en) * | 1989-06-06 | 1991-01-01 | Carter-Wallace, Inc. | Conversion of diethyl phenylmalonate to 2-phenyl-1,3-propanediol |
US5532416A (en) | 1994-07-20 | 1996-07-02 | Monsanto Company | Benzoyl derivatives and synthesis thereof |
JPH05271129A (ja) | 1992-01-30 | 1993-10-19 | Idemitsu Petrochem Co Ltd | (ペルフルオロデカリン)アルコール体 |
DE4212628A1 (de) | 1992-04-15 | 1993-10-21 | Manfred Dr Metzler | Neue Bis-phenyl-hexene |
FR2706898B1 (es) | 1993-06-25 | 1995-09-08 | Union Pharma Scient Appl | |
JPH07316131A (ja) * | 1994-05-27 | 1995-12-05 | Mitsubishi Chem Corp | ピロール誘導体の製造方法 |
US5808107A (en) * | 1997-10-31 | 1998-09-15 | Board Of Trustees Operating Michigan State University | Process for the preparation of hydroxy substituted gamma butyrolactones |
JP4079505B2 (ja) | 1998-04-28 | 2008-04-23 | 田辺三菱製薬株式会社 | 2−アミノ−2−[2−(4−オクチルフェニル)エチル]プロパン−1,3−ジオールの新規な製造法 |
TW593256B (en) | 1999-11-16 | 2004-06-21 | Hormos Medical Oy Ltd | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
SI21655A (sl) | 2003-12-29 | 2005-06-30 | LEK farmacevtska dru�ba d.d. | Sinteza optično čistega (R)-5-(2-aminopropil)-2-metoksibenzensulfonamida |
US8853224B2 (en) | 2006-09-07 | 2014-10-07 | Industrial Research Limited | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases |
ES2389961T3 (es) * | 2007-02-14 | 2012-11-05 | Hormos Medical Ltd. | Método para la preparación de derivados de trifenilbuteno con valor terapéutico |
WO2009081789A1 (ja) | 2007-12-26 | 2009-07-02 | Banyu Pharmaceutical Co., Ltd. | スルホニル置換六員環誘導体 |
SI2526080T1 (sl) | 2010-01-19 | 2014-07-31 | Cambrex Karlskoga Ab | Novi postopki za izdelavo benzofenonskih derivatov |
US8277699B2 (en) | 2010-04-30 | 2012-10-02 | Transistions Optical, Inc. | Photochromic materials that include 6-amino substituted indeno-fused naphthopyrans |
JP2013224263A (ja) | 2010-08-19 | 2013-10-31 | Taisho Pharmaceutical Co Ltd | 4−イソプロピルフェニルグルシトール化合物 |
WO2012089607A1 (en) * | 2010-12-28 | 2012-07-05 | Glaxo Group Limited | Novel compounds with a 3a-azabicyclo [4.1.0] heptane core acting on orexin receptors |
WO2012089606A1 (en) * | 2010-12-28 | 2012-07-05 | Glaxo Group Limited | Azabicyclo [4.1.0] hept - 4 - yl derivatives as human orexin receptor antagonists |
CN103242142A (zh) | 2012-02-13 | 2013-08-14 | 天津药物研究院 | 欧司哌米芬及其中间体的制备方法 |
US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
EP2909163A1 (en) * | 2012-10-19 | 2015-08-26 | Fermion Oy | A process for the preparation of ospemifene |
CN104030896A (zh) | 2013-03-07 | 2014-09-10 | 天津药物研究院 | 一种简易去除欧司哌米芬特异杂质的方法 |
CN107074722A (zh) * | 2014-09-16 | 2017-08-18 | 盐野义制药株式会社 | 三苯基丁烯衍生物的制造方法 |
US10138190B2 (en) | 2015-01-09 | 2018-11-27 | Glenmark Pharmaceuticals Limited | Process for preparation of ospemifene |
-
2017
- 2017-03-14 CA CA3016545A patent/CA3016545A1/en active Pending
- 2017-03-14 US US16/085,110 patent/US10472312B2/en active Active
- 2017-03-14 BR BR112018017117-4A patent/BR112018017117B1/pt active IP Right Grant
- 2017-03-14 WO PCT/JP2017/010159 patent/WO2017159669A1/ja active Application Filing
- 2017-03-14 EP EP20208147.7A patent/EP3835285A1/en not_active Withdrawn
- 2017-03-14 CN CN201780003403.3A patent/CN108137457B/zh active Active
- 2017-03-14 EP EP17766668.2A patent/EP3415491B1/en active Active
- 2017-03-14 MX MX2018010466A patent/MX2018010466A/es unknown
- 2017-03-14 JP JP2018505944A patent/JPWO2017159669A1/ja active Pending
- 2017-03-14 AU AU2017232476A patent/AU2017232476B2/en active Active
- 2017-03-14 EA EA201891918A patent/EA039048B1/ru unknown
- 2017-03-14 KR KR1020187024120A patent/KR102377433B1/ko active IP Right Grant
-
2018
- 2018-09-10 CO CONC2018/0009436A patent/CO2018009436A2/es unknown
- 2018-09-14 CL CL2018002641A patent/CL2018002641A1/es unknown
- 2018-12-10 HK HK18115760.6A patent/HK1256626A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2017159669A1 (ja) | 2017-09-21 |
KR20180122330A (ko) | 2018-11-12 |
AU2017232476A1 (en) | 2018-10-04 |
EA201891918A1 (ru) | 2019-02-28 |
HK1256626A1 (zh) | 2019-09-27 |
KR102377433B1 (ko) | 2022-03-23 |
AU2017232476B2 (en) | 2019-10-03 |
EP3835285A1 (en) | 2021-06-16 |
CA3016545A1 (en) | 2017-09-21 |
US20190084910A1 (en) | 2019-03-21 |
US10472312B2 (en) | 2019-11-12 |
BR112018017117A2 (pt) | 2018-12-26 |
BR112018017117B1 (pt) | 2021-11-16 |
EP3415491A4 (en) | 2019-02-27 |
CN108137457A (zh) | 2018-06-08 |
EP3415491B1 (en) | 2020-11-18 |
MX2018010466A (es) | 2019-01-14 |
EP3415491A1 (en) | 2018-12-19 |
EA039048B1 (ru) | 2021-11-26 |
CN108137457B (zh) | 2022-09-06 |
JPWO2017159669A1 (ja) | 2019-01-24 |
CO2018009436A2 (es) | 2018-10-10 |
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