CL2017000106A1 - Novedosas pirimidinas 2,5-sustituidas como inhibidores pde4 . - Google Patents

Novedosas pirimidinas 2,5-sustituidas como inhibidores pde4 .

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Publication number
CL2017000106A1
CL2017000106A1 CL2017000106A CL2017000106A CL2017000106A1 CL 2017000106 A1 CL2017000106 A1 CL 2017000106A1 CL 2017000106 A CL2017000106 A CL 2017000106A CL 2017000106 A CL2017000106 A CL 2017000106A CL 2017000106 A1 CL2017000106 A1 CL 2017000106A1
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CL
Chile
Prior art keywords
innovative
pde4 inhibitors
substituted pyrimidines
medications
substitutes
Prior art date
Application number
CL2017000106A
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English (en)
Inventor
Antonio Nardi
Florian Jakob
Ingo Konetzki
Tobias Craan
Christian Hesslinger
Original Assignee
Gruenenthal Gmbh
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Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of CL2017000106A1 publication Critical patent/CL2017000106A1/es

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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

<p>COMPUESTOS CONDENSADOS SUSTITUIDOS DE PIRIMIDINA DE FÓRMULA GENERAL (I):</p> <p>* incluir figura de estructura de hoja resumen (pag 159)</p> <p>EN LOS CUALES LOS GRUPOS QUÍMICOS, SUSTITUYENTES E ÍNDICES SON TAL COMO SE LOS DEFINE EN LA DESCRIPCIÓN, Y SU USO COMO MEDICAMENTOS, EN PARTICULAR COMO MEDICAMENTOS PARA EL TRATAMIENTO DE CONDICIONES Y ENFERMEDADES QUE SE PUEDEN TRATAR POR INHIBICIÓN DE LA ENZIMA PDE4.</p>
CL2017000106A 2014-07-16 2017-01-13 Novedosas pirimidinas 2,5-sustituidas como inhibidores pde4 . CL2017000106A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14002450 2014-07-16

Publications (1)

Publication Number Publication Date
CL2017000106A1 true CL2017000106A1 (es) 2017-08-04

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ID=51210959

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CL2017000106A CL2017000106A1 (es) 2014-07-16 2017-01-13 Novedosas pirimidinas 2,5-sustituidas como inhibidores pde4 .

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US (2) US9546158B2 (es)
EP (2) EP3415510A1 (es)
JP (1) JP6723217B2 (es)
KR (1) KR20170032421A (es)
CN (1) CN106660996B (es)
AR (1) AR101198A1 (es)
AU (1) AU2015291475B2 (es)
BR (1) BR112017000830A2 (es)
CA (1) CA2955053A1 (es)
CL (1) CL2017000106A1 (es)
CO (1) CO2017001506A2 (es)
EA (1) EA201790206A1 (es)
EC (1) ECSP17010481A (es)
IL (1) IL250026A0 (es)
MX (1) MX366839B (es)
PE (1) PE20170251A1 (es)
TW (1) TW201613896A (es)
WO (1) WO2016008590A1 (es)
ZA (1) ZA201701131B (es)

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AR101198A1 (es) 2014-07-16 2016-11-30 Gruenenthal Gmbh Pirimidinas 2,5-sustituidas como inhibidores de pde4b
AR101196A1 (es) 2014-07-16 2016-11-30 Gruenenthal Gmbh Compuestos de pirimidina sustituidos
WO2018065849A1 (en) 2016-10-03 2018-04-12 Koninklijke Philips N.V. Radiopaque arrangement of electronic components in intra-cardiac echocardiography (ice) catheter
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WO2018234354A1 (en) 2017-06-20 2018-12-27 Grünenthal GmbH NOVEL SUBSTITUTED 3-INDOLE AND 3-INDAZOLE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS
WO2018234353A1 (en) 2017-06-20 2018-12-27 Grünenthal GmbH NOVEL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS INHIBITORS OF PHOSPHODIESTERASE
WO2020083878A1 (en) 2018-10-25 2020-04-30 Merck Patent Gmbh 5-azaindazole derivatives as adenosine receptor antagonists
CN110156785B (zh) * 2019-04-15 2020-08-28 浙江大学 吲唑类化合物及其制备方法和应用
US20240066027A1 (en) * 2020-12-03 2024-02-29 Domain Therapeutics Novel par-2 inhibitors

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