CL2015000359A1 - Compuestos derivados de pirrolopirazoles sustituidos, bloqueadores del canal de calcio tipo n; y composicion farmaceutica que los comprende. - Google Patents

Compuestos derivados de pirrolopirazoles sustituidos, bloqueadores del canal de calcio tipo n; y composicion farmaceutica que los comprende.

Info

Publication number
CL2015000359A1
CL2015000359A1 CL2015000359A CL2015000359A CL2015000359A1 CL 2015000359 A1 CL2015000359 A1 CL 2015000359A1 CL 2015000359 A CL2015000359 A CL 2015000359A CL 2015000359 A CL2015000359 A CL 2015000359A CL 2015000359 A1 CL2015000359 A1 CL 2015000359A1
Authority
CL
Chile
Prior art keywords
pyrrolopyrazoles
substituted
pharmaceutical composition
type
calcium channel
Prior art date
Application number
CL2015000359A
Other languages
English (en)
Inventor
Zhihua Sui
Michael P Winters
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49170857&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015000359(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2015000359A1 publication Critical patent/CL2015000359A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2015000359A 2012-08-16 2015-02-16 Compuestos derivados de pirrolopirazoles sustituidos, bloqueadores del canal de calcio tipo n; y composicion farmaceutica que los comprende. CL2015000359A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261683780P 2012-08-16 2012-08-16

Publications (1)

Publication Number Publication Date
CL2015000359A1 true CL2015000359A1 (es) 2015-04-24

Family

ID=49170857

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000359A CL2015000359A1 (es) 2012-08-16 2015-02-16 Compuestos derivados de pirrolopirazoles sustituidos, bloqueadores del canal de calcio tipo n; y composicion farmaceutica que los comprende.

Country Status (19)

Country Link
US (1) US8846949B2 (es)
EP (1) EP2885304B8 (es)
JP (1) JP6250674B2 (es)
KR (1) KR20150042271A (es)
CN (1) CN104936960B (es)
AU (1) AU2013302473B2 (es)
BR (1) BR112015003359A2 (es)
CA (1) CA2882127A1 (es)
CL (1) CL2015000359A1 (es)
CR (1) CR20150070A (es)
EA (1) EA201590379A1 (es)
ES (1) ES2607839T3 (es)
IL (1) IL237192A0 (es)
IN (1) IN2015DN01230A (es)
MX (1) MX2015002039A (es)
PE (1) PE20151139A1 (es)
PH (1) PH12015500310A1 (es)
SG (1) SG11201501133WA (es)
WO (1) WO2014028805A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9974775B2 (en) 2013-08-16 2018-05-22 Janssen Pharmaceutica Nv Substituted imidazoles as N-type calcium channel blockers

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6262732B2 (ja) 2012-08-16 2018-01-17 ヤンセン ファーマシューティカ エヌ．ベー． Ｎ型カルシウムチャネル遮断剤としての置換ピラゾール
WO2018222598A1 (en) 2017-05-31 2018-12-06 Chemocentryx, Inc. 6-5 FUSED RINGS AS C5a INHIBITORS
KR102586710B1 (ko) 2017-05-31 2023-10-10 케모센트릭스, 인크. C5a 억제제로서의 5-5 융합 고리
JP7253557B2 (ja) * 2017-12-22 2023-04-06 ケモセントリックス，インコーポレイティド Ｃ５ａＲ阻害剤としてのジアリール置換５，５－縮合環化合物
EP3728203B1 (en) 2017-12-22 2024-03-13 ChemoCentryx, Inc. DIARYL SUBSTITUTED 6,5-FUSED RING COMPOUNDS AS C5aR INHIBITORS
CA3095184A1 (en) 2018-04-02 2019-10-10 Chemocentryx, Inc. Prodrugs of fused-bicyclic c5ar antagonists
CN112300169B (zh) * 2019-07-26 2022-03-04 上海美迪西生物医药股份有限公司 吡咯并吡唑类衍生物、其制备方法及其在医药上的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1287174B1 (it) * 1996-11-15 1998-08-04 Angelini Ricerche Spa Diaril-ciclometilenpirazoli farmacologicamente attivi,procedimento per prepararli e composizioni farmaceutiche che li contengono
JP2006522130A (ja) * 2003-04-03 2006-09-28 メルク　エンド　カムパニー　インコーポレーテッド ナトリウムチャンネル遮断薬としてのビアリール置換ピラゾール
US7145012B2 (en) * 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
DK1668014T3 (da) * 2003-09-17 2009-04-20 Janssen Pharmaceutica Nv Kondenserede heterocykliske forbindelser som serotoninreceptormodulatorer
FR2864958B1 (fr) * 2004-01-12 2006-02-24 Sanofi Synthelabo Derive de n-[(1,5-diphenyl-1h-pyrazol-3-yl)methyl] sulfonamide, leur preparation et leur application en therapeutique.
AU2005222402A1 (en) * 2004-03-08 2005-09-22 Wyeth Ion channel modulators
US20070191448A1 (en) * 2004-03-08 2007-08-16 Robert Zelle Ion channel modulators

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9974775B2 (en) 2013-08-16 2018-05-22 Janssen Pharmaceutica Nv Substituted imidazoles as N-type calcium channel blockers

Also Published As

Publication number Publication date
JP2015524853A (ja) 2015-08-27
PH12015500310A1 (en) 2015-04-20
EP2885304A1 (en) 2015-06-24
CN104936960A (zh) 2015-09-23
EP2885304B8 (en) 2016-12-07
IN2015DN01230A (en) 2015-06-26
US8846949B2 (en) 2014-09-30
AU2013302473B2 (en) 2017-08-10
IL237192A0 (en) 2015-04-30
EP2885304B1 (en) 2016-09-21
MX2015002039A (es) 2016-01-22
BR112015003359A2 (pt) 2017-07-04
EA201590379A1 (ru) 2015-06-30
SG11201501133WA (en) 2015-04-29
CR20150070A (es) 2015-05-18
JP6250674B2 (ja) 2017-12-20
CN104936960B (zh) 2016-12-28
KR20150042271A (ko) 2015-04-20
US20140051688A1 (en) 2014-02-20
WO2014028805A1 (en) 2014-02-20
ES2607839T3 (es) 2017-04-04
PE20151139A1 (es) 2015-08-07
AU2013302473A1 (en) 2015-02-26
CA2882127A1 (en) 2014-02-20

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