CL2013002985A1 - Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer. - Google Patents

Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer.

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Publication number
CL2013002985A1
CL2013002985A1 CL2013002985A CL2013002985A CL2013002985A1 CL 2013002985 A1 CL2013002985 A1 CL 2013002985A1 CL 2013002985 A CL2013002985 A CL 2013002985A CL 2013002985 A CL2013002985 A CL 2013002985A CL 2013002985 A1 CL2013002985 A1 CL 2013002985A1
Authority
CL
Chile
Prior art keywords
diseases
aminomethylphenyl
sphingosine
immunosuppression
atherosclerosis
Prior art date
Application number
CL2013002985A
Other languages
English (en)
Inventor
Wha Bin Im
Janet A Takeuchi
Ling Li
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CL2013002985A1 publication Critical patent/CL2013002985A1/es

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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
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CL2013002985A 2011-04-14 2013-10-14 Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer. CL2013002985A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161475352P 2011-04-14 2011-04-14

Publications (1)

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CL2013002985A1 true CL2013002985A1 (es) 2014-06-13

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CL2013002985A CL2013002985A1 (es) 2011-04-14 2013-10-14 Compuestos derivados de aminometilfenilo biciclico, como moduladores del receptor de esfingosina-1-fosfato; composicion farmaceutica que los comprende; y su uso para tratar enfermedades oculares, enfermedades inflamatorias, enfermedades autoinmunes e inmunosupresion, aterosclerosis, enfermedad de alzheimer.

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US (4) US8716267B2 (es)
EP (2) EP2697212B1 (es)
JP (1) JP2014511878A (es)
KR (1) KR20140048874A (es)
CN (1) CN103619828A (es)
AU (2) AU2012242827A1 (es)
BR (1) BR112013026507A2 (es)
CA (2) CA2833313A1 (es)
CL (1) CL2013002985A1 (es)
IL (1) IL228850A0 (es)
MX (1) MX2013011979A (es)
RU (1) RU2013150173A (es)
SG (1) SG194184A1 (es)
WO (2) WO2012142288A1 (es)
ZA (1) ZA201307796B (es)

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WO2012142288A1 (en) * 2011-04-14 2012-10-18 Allergan, Inc. Phenyl bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators
CN112851562A (zh) * 2021-01-22 2021-05-28 烟台显华化工科技有限公司 一种芳香环液晶化合物及其液晶组合物和应用

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EP1638551B1 (en) * 2003-05-19 2011-12-21 Irm Llc Immunosuppressant compounds and compositions
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JP2009269819A (ja) * 2006-08-25 2009-11-19 Asahi Kasei Pharma Kk アミン化合物
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SG194184A1 (en) 2013-11-29
AU2012242652A1 (en) 2013-10-31
US8541582B2 (en) 2013-09-24
US8946195B2 (en) 2015-02-03
WO2012142377A1 (en) 2012-10-18
AU2012242827A1 (en) 2013-10-31
US20120264718A1 (en) 2012-10-18
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US8653050B2 (en) 2014-02-18
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US20130338108A1 (en) 2013-12-19
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CN103619828A (zh) 2014-03-05
EP2697212A1 (en) 2014-02-19
BR112013026507A2 (pt) 2016-12-27
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