CL2012003489A1 - Proceso para obtecion de yoduro por reaccion entre una iodo-amida y un acido carboxilico. - Google Patents

Proceso para obtecion de yoduro por reaccion entre una iodo-amida y un acido carboxilico.

Info

Publication number
CL2012003489A1
CL2012003489A1 CL2012003489A CL2012003489A CL2012003489A1 CL 2012003489 A1 CL2012003489 A1 CL 2012003489A1 CL 2012003489 A CL2012003489 A CL 2012003489A CL 2012003489 A CL2012003489 A CL 2012003489A CL 2012003489 A1 CL2012003489 A1 CL 2012003489A1
Authority
CL
Chile
Prior art keywords
iodide
iodine
amide
obtaining
reaction
Prior art date
Application number
CL2012003489A
Other languages
English (en)
Spanish (es)
Inventor
Gennady Nisnevich
Mark Gandeman
Kseniya Kulbitski
Original Assignee
Technion R & D Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion R & D Foundation Ltd filed Critical Technion R & D Foundation Ltd
Publication of CL2012003489A1 publication Critical patent/CL2012003489A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/12Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/18Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/317Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C67/32Decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/38Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/60Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
    • C07C2603/62Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing three- or four-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/90Ring systems containing bridged rings containing more than four rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
CL2012003489A 2010-06-10 2012-12-10 Proceso para obtecion de yoduro por reaccion entre una iodo-amida y un acido carboxilico. CL2012003489A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35342710P 2010-06-10 2010-06-10
US201061427925P 2010-12-29 2010-12-29

Publications (1)

Publication Number Publication Date
CL2012003489A1 true CL2012003489A1 (es) 2013-10-18

Family

ID=44318441

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012003489A CL2012003489A1 (es) 2010-06-10 2012-12-10 Proceso para obtecion de yoduro por reaccion entre una iodo-amida y un acido carboxilico.

Country Status (4)

Country Link
US (1) US8822516B2 (https=)
JP (1) JP5603487B2 (https=)
CL (1) CL2012003489A1 (https=)
WO (1) WO2011154953A1 (https=)

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Publication number Priority date Publication date Assignee Title
JP5603487B2 (ja) 2010-06-10 2014-10-08 テクニオン リサーチ アンド ディベラップメント ファウンデイション リミテッド ヨウ化物の調製のためのプロセス
CA2807546C (en) 2010-08-10 2022-08-23 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
IL229326A (en) 2013-11-07 2015-11-30 Technion Res & Dev Foundation Process for making n-iodine-affluent
AU2015264418A1 (en) 2014-05-19 2016-11-10 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2016003929A1 (en) 2014-07-01 2016-01-07 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
JP6534154B2 (ja) * 2015-09-02 2019-06-26 国立大学法人千葉大学 N−アルキルイミド化合物の製造方法
WO2017060906A1 (en) 2015-10-07 2017-04-13 Technion Research & Development Foundation Limited Process for the preparation of organic halides
JP2018538239A (ja) * 2015-10-07 2018-12-27 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッドTechnion Research And Development Foundation Ltd. 有機臭化物の調製方法
MX389349B (es) 2016-06-30 2025-03-20 Qpex Biopharma Inc Derivados de ácido borónico y usos terapéuticos de los mismos.
CN106748604B (zh) * 2016-11-18 2020-06-05 湘潭大学 一种基于芳烃羧酸脱羧反应合成单碘代芳烃或二碘代芳烃的方法
US11286270B2 (en) 2017-10-11 2022-03-29 Qpex Biopharma, Inc. Boronic acid derivatives and synthesis thereof
WO2019199459A1 (en) * 2018-04-12 2019-10-17 Exxonmobil Chemical Patents Inc. Preparation and use of biphenyl carboxylic acids, alcohols, and esters
EP3781576B1 (en) 2018-04-20 2024-06-12 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN108929346A (zh) * 2018-08-16 2018-12-04 陕西师范大学 一种高效立体选择性的构建α-和β-糖苷键的方法
AU2021266715A1 (en) 2020-05-05 2022-11-17 Qpex Biopharma, Inc. Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof
CN112723984B (zh) * 2021-01-14 2022-03-01 上海交通大学 一种分离间溴碘苯和邻溴碘苯的方法
JP7728864B2 (ja) * 2021-05-28 2025-08-25 住友化学株式会社 シクロアルキルブロミドの製造方法

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US3652682A (en) 1968-02-28 1972-03-28 Us Agriculture Process for the preparation of alkyl perfluoroalkyl and aryl iodides
US3666820A (en) 1968-02-28 1972-05-30 Us Agriculture Process for the preparation of alkyl, perfluoroalkyl and aryl iodides
US3531535A (en) 1968-02-28 1970-09-29 Us Agriculture Process for the preparation of alkyl,perfluoroalkyl and aryl iodides
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
IL150982A (en) 2002-07-30 2007-02-11 Ori Lerman Process for making Donafzil
US7138555B2 (en) 2004-04-20 2006-11-21 Xerox Corporation Process for preparing iodoaromatic compounds and using the same
EP1928599B1 (en) 2005-09-02 2012-10-03 Japan Science and Technology Agency Lewis acid catalyzed halogenation of activated carbon atoms
KR20190126460A (ko) 2007-02-09 2019-11-11 메타베이시스 테라퓨틱스, 인크. 글루카곤 수용체의 길항제
WO2008143141A1 (ja) 2007-05-18 2008-11-27 Nippoh Chemicals Co., Ltd. ハロゲン化芳香族化合物の製造方法
GB0710865D0 (en) 2007-06-06 2007-07-18 Glaxo Group Ltd Novel compounds
EP2110369A1 (en) 2008-03-25 2009-10-21 Semiconductor Energy Laboratory Co., Ltd. Method of synthesizing 9-aryl-10-iodoanthracene derivative and light-emitting material
JP5295613B2 (ja) * 2008-04-07 2013-09-18 日宝化学株式会社 ヨウ素化芳香族化合物の製造方法
AR076014A1 (es) 2009-04-02 2011-05-11 Sanofi Aventis Derivados de 3- (1,4) oxazepan -4-pirimidona
JP5603487B2 (ja) 2010-06-10 2014-10-08 テクニオン リサーチ アンド ディベラップメント ファウンデイション リミテッド ヨウ化物の調製のためのプロセス
EP2646026B1 (en) 2010-12-03 2014-10-15 Allergan, Inc. Novel oxadiazole derivatives as sphingosine 1-phosphate (s1p) receptor modulators
CA2819598A1 (en) 2010-12-03 2012-06-07 Allergan, Inc. Novel phenyl oxadiazole derivatives as sphingosine 1-phosphate (s1p) receptor modulators

Also Published As

Publication number Publication date
US20130165658A1 (en) 2013-06-27
JP5603487B2 (ja) 2014-10-08
WO2011154953A1 (en) 2011-12-15
JP2013533231A (ja) 2013-08-22
US8822516B2 (en) 2014-09-02

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