CL2012003416A1 - Complejos de fosfoplatino; composicion farmaceutica que comprende uno o mas de estos complejos; y su uso para tratar una enfermedad proliferativa seleccionada de cancer de ovarios, cancer testicular, cancer de pulmon de celula pequeña, cancer de pulmon de celula no pequeña, cancer de cabeza y cuello, cancer de piel, entre otros. - Google Patents
Complejos de fosfoplatino; composicion farmaceutica que comprende uno o mas de estos complejos; y su uso para tratar una enfermedad proliferativa seleccionada de cancer de ovarios, cancer testicular, cancer de pulmon de celula pequeña, cancer de pulmon de celula no pequeña, cancer de cabeza y cuello, cancer de piel, entre otros.Info
- Publication number
- CL2012003416A1 CL2012003416A1 CL2012003416A CL2012003416A CL2012003416A1 CL 2012003416 A1 CL2012003416 A1 CL 2012003416A1 CL 2012003416 A CL2012003416 A CL 2012003416A CL 2012003416 A CL2012003416 A CL 2012003416A CL 2012003416 A1 CL2012003416 A1 CL 2012003416A1
- Authority
- CL
- Chile
- Prior art keywords
- cancer
- complexes
- small cell
- cell lung
- lung cancer
- Prior art date
Links
- 206010033128 Ovarian cancer Diseases 0.000 title 1
- 206010061535 Ovarian neoplasm Diseases 0.000 title 1
- KTCQVFPGCRGZPS-UHFFFAOYSA-N P(=O)(=O)[Pt] Chemical class P(=O)(=O)[Pt] KTCQVFPGCRGZPS-UHFFFAOYSA-N 0.000 title 1
- 208000000453 Skin Neoplasms Diseases 0.000 title 1
- 206010041067 Small cell lung cancer Diseases 0.000 title 1
- 208000024313 Testicular Neoplasms Diseases 0.000 title 1
- 206010057644 Testis cancer Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 201000010536 head and neck cancer Diseases 0.000 title 1
- 208000014829 head and neck neoplasm Diseases 0.000 title 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
- 201000000849 skin cancer Diseases 0.000 title 1
- 208000000587 small cell lung carcinoma Diseases 0.000 title 1
- 201000003120 testicular cancer Diseases 0.000 title 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/245—Bismuth; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35151410P | 2010-06-04 | 2010-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012003416A1 true CL2012003416A1 (es) | 2013-09-06 |
Family
ID=44627266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012003416A CL2012003416A1 (es) | 2010-06-04 | 2012-12-04 | Complejos de fosfoplatino; composicion farmaceutica que comprende uno o mas de estos complejos; y su uso para tratar una enfermedad proliferativa seleccionada de cancer de ovarios, cancer testicular, cancer de pulmon de celula pequeña, cancer de pulmon de celula no pequeña, cancer de cabeza y cuello, cancer de piel, entre otros. |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US9688709B2 (es) |
| EP (1) | EP2575802B1 (es) |
| JP (1) | JP5860872B2 (es) |
| KR (1) | KR101775410B1 (es) |
| CN (6) | CN108299508A (es) |
| AP (1) | AP3480A (es) |
| AU (1) | AU2011261381B2 (es) |
| BR (1) | BR112012030927B1 (es) |
| CA (1) | CA2800898C (es) |
| CL (1) | CL2012003416A1 (es) |
| CO (1) | CO6640302A2 (es) |
| CY (1) | CY1118466T1 (es) |
| DK (1) | DK2575802T3 (es) |
| EA (1) | EA021526B1 (es) |
| ES (1) | ES2606855T3 (es) |
| HR (1) | HRP20170225T1 (es) |
| HU (1) | HUE030249T2 (es) |
| IL (1) | IL223405B (es) |
| LT (1) | LT2575802T (es) |
| MX (1) | MX2012014174A (es) |
| MY (1) | MY162902A (es) |
| NZ (1) | NZ603952A (es) |
| PL (1) | PL2575802T3 (es) |
| PT (1) | PT2575802T (es) |
| RS (1) | RS55714B1 (es) |
| SG (1) | SG185722A1 (es) |
| SI (1) | SI2575802T1 (es) |
| SM (1) | SMT201700056B (es) |
| WO (1) | WO2011153365A1 (es) |
| ZA (1) | ZA201209007B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108299508A (zh) | 2010-06-04 | 2018-07-20 | 俄亥俄大学 | 磷铂及其在治疗癌症中的用途 |
| US20130236568A1 (en) * | 2011-01-12 | 2013-09-12 | Ohio University | Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof |
| CN104010508B (zh) * | 2011-10-05 | 2017-03-15 | 理辛德拉·N·博斯 | 用于大规模制备磷铂类抗肿瘤剂的高效方法 |
| JP6027619B2 (ja) * | 2011-10-05 | 2016-11-16 | ラシンドラ・エヌ・ボーズ | ホスファプラチン系抗腫瘍剤の大規模調製のための効率的プロセス |
| SI2855496T1 (sl) * | 2012-05-24 | 2017-04-26 | Phosplatin Therapeutics Llc | Sintezni postopki in postopki čiščenja za fosfaplatinove spojine in njihove uporabe |
| WO2014130776A1 (en) | 2013-02-22 | 2014-08-28 | University Of Houston | Phosphaplatins as neuroprotective agents |
| EP3107534A4 (en) * | 2014-02-19 | 2017-09-06 | The University Of Houston System | Compositions and methods for the treatment of neurodegenerative diseases |
| CA3020166A1 (en) * | 2016-04-06 | 2017-10-12 | Phosplatin Therapeutics Llc | Phosphaplatin liquid formulations |
| KR20190103258A (ko) | 2017-01-06 | 2019-09-04 | 포스플라틴 테라퓨틱스 엘엘씨 | 뼈 또는 혈액 암의 치료를 위한 치료제로서의 포스파플라틴 화합물 |
| AU2018327339B2 (en) * | 2017-09-08 | 2023-10-12 | Promontory Therapeutics Inc. | Phosphaplatin compounds as immuno-modulatory agents and therapeutic uses thereof |
| US20240009212A1 (en) * | 2020-10-20 | 2024-01-11 | Promontory Therapeutics Inc. | Phosphaplatin compounds as therapeutic agents selectively targeting highly glycolytic tumor cells and methods thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234500A (en) | 1979-03-07 | 1980-11-18 | Engelhard Minerals & Chemicals Corporation | Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes |
| US4291027A (en) | 1979-03-07 | 1981-09-22 | Engelhard Minerals & Chemicals Corp. | Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes |
| CA2017739A1 (en) | 1989-07-18 | 1991-01-18 | Leslie S. Hollis | Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents |
| AUPR330201A0 (en) | 2001-02-23 | 2001-03-22 | University Of Sydney, The | Metal complexes and therapeutic uses thereof |
| DE10314780A1 (de) | 2003-03-19 | 2004-09-30 | Ktb Tumorforschungsgesellschaft Mbh | Proteinbindende Derivate von Platinkomplexen mit Cyclobutan-1,1-dicarboxylatliganden |
| WO2004098524A2 (en) | 2003-05-02 | 2004-11-18 | Aronex Pharmaceuticals, Inc. | Lipid platinum complexes and methods of use thereof |
| JP4463274B2 (ja) | 2003-06-27 | 2010-05-19 | 明 小谷 | ビスホスホネート錯体 |
| EP2177525A1 (en) | 2007-07-06 | 2010-04-21 | TMRC Co., Ltd. | Metal complex compound, cancer therapeutic composition comprising the metal complex compound as active ingredient, and intermediate for production of the metal complex compound |
| DK2173337T3 (da) * | 2007-08-06 | 2014-09-15 | Univ Ohio | Phosphaplatiner og deres anvendelse i behandlingen af cancer, der er resistent over for cisplatin og carboplatin |
| WO2011125911A1 (ja) | 2010-03-31 | 2011-10-13 | 国立大学法人金沢大学 | 金属錯体およびこれを有効成分として含有する抗がん剤 |
| CN108299508A (zh) | 2010-06-04 | 2018-07-20 | 俄亥俄大学 | 磷铂及其在治疗癌症中的用途 |
| US20130236568A1 (en) | 2011-01-12 | 2013-09-12 | Ohio University | Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof |
| JP6027619B2 (ja) * | 2011-10-05 | 2016-11-16 | ラシンドラ・エヌ・ボーズ | ホスファプラチン系抗腫瘍剤の大規模調製のための効率的プロセス |
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2011
- 2011-06-02 CN CN201810150614.6A patent/CN108299508A/zh active Pending
- 2011-06-02 DK DK11726567.8T patent/DK2575802T3/en active
- 2011-06-02 JP JP2013513350A patent/JP5860872B2/ja active Active
- 2011-06-02 EA EA201270812A patent/EA021526B1/ru unknown
- 2011-06-02 RS RS20170139A patent/RS55714B1/sr unknown
- 2011-06-02 CA CA2800898A patent/CA2800898C/en active Active
- 2011-06-02 HU HUE11726567A patent/HUE030249T2/en unknown
- 2011-06-02 SI SI201131103A patent/SI2575802T1/sl unknown
- 2011-06-02 MX MX2012014174A patent/MX2012014174A/es active IP Right Grant
- 2011-06-02 AP AP2012006594A patent/AP3480A/xx active
- 2011-06-02 KR KR1020137000158A patent/KR101775410B1/ko not_active Application Discontinuation
- 2011-06-02 WO PCT/US2011/038948 patent/WO2011153365A1/en active Application Filing
- 2011-06-02 CN CN201810150598.0A patent/CN108186651A/zh active Pending
- 2011-06-02 ES ES11726567.8T patent/ES2606855T3/es active Active
- 2011-06-02 PT PT117265678T patent/PT2575802T/pt unknown
- 2011-06-02 CN CN201810150487.XA patent/CN108210516A/zh active Pending
- 2011-06-02 BR BR112012030927-7A patent/BR112012030927B1/pt active IP Right Grant
- 2011-06-02 LT LTEP11726567.8T patent/LT2575802T/lt unknown
- 2011-06-02 EP EP11726567.8A patent/EP2575802B1/en active Active
- 2011-06-02 CN CN2011800387165A patent/CN103037859A/zh active Pending
- 2011-06-02 NZ NZ603952A patent/NZ603952A/en unknown
- 2011-06-02 CN CN201810150470.4A patent/CN108392490A/zh active Pending
- 2011-06-02 AU AU2011261381A patent/AU2011261381B2/en active Active
- 2011-06-02 SG SG2012086229A patent/SG185722A1/en unknown
- 2011-06-02 CN CN201810150496.9A patent/CN108409795A/zh active Pending
- 2011-06-02 PL PL11726567T patent/PL2575802T3/pl unknown
- 2011-06-02 US US13/701,313 patent/US9688709B2/en active Active
- 2011-06-02 MY MYPI2012005178A patent/MY162902A/en unknown
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2012
- 2012-11-28 ZA ZA2012/09007A patent/ZA201209007B/en unknown
- 2012-12-03 IL IL223405A patent/IL223405B/en active IP Right Grant
- 2012-12-04 CL CL2012003416A patent/CL2012003416A1/es unknown
- 2012-12-04 CO CO12219958A patent/CO6640302A2/es not_active Application Discontinuation
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2016
- 2016-12-22 CY CY20161101332T patent/CY1118466T1/el unknown
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2017
- 2017-01-25 SM SM201700056T patent/SMT201700056B/it unknown
- 2017-02-10 HR HRP20170225TT patent/HRP20170225T1/hr unknown
- 2017-05-24 US US15/604,209 patent/US10385083B2/en active Active
- 2017-05-24 US US15/604,237 patent/US10364264B2/en active Active
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2019
- 2019-06-26 US US16/453,303 patent/US10759820B2/en active Active
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