CL2012001358A1 - Polimero con esqueleto lineal de tipo acrilico y/o metacrilico al que estan ligados injertos de alfa-tocoferol, por medio de un espaciador formado en parte por la menos una funcion hidroloizable yn porque el reparto de dichos injertos al nivel de dichos esqueleto es aleatorio; procedimiento de preparacion; composicion. - Google Patents

Polimero con esqueleto lineal de tipo acrilico y/o metacrilico al que estan ligados injertos de alfa-tocoferol, por medio de un espaciador formado en parte por la menos una funcion hidroloizable yn porque el reparto de dichos injertos al nivel de dichos esqueleto es aleatorio; procedimiento de preparacion; composicion.

Info

Publication number
CL2012001358A1
CL2012001358A1 CL2012001358A CL2012001358A CL2012001358A1 CL 2012001358 A1 CL2012001358 A1 CL 2012001358A1 CL 2012001358 A CL2012001358 A CL 2012001358A CL 2012001358 A CL2012001358 A CL 2012001358A CL 2012001358 A1 CL2012001358 A1 CL 2012001358A1
Authority
CL
Chile
Prior art keywords
grafts
skeleton
polymer
alpha
acrylic
Prior art date
Application number
CL2012001358A
Other languages
English (en)
Inventor
You-Ping Chan
Olivier Breyne
Alain Constancis
Original Assignee
Flamel Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Tech filed Critical Flamel Tech
Publication of CL2012001358A1 publication Critical patent/CL2012001358A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/302—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and two or more oxygen atoms in the alcohol moiety
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Graft Or Block Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Polímero que posee un esqueleto lineal de tipo acrílico y/o metacrílico al que están ligados injertos de alfatocoferol, en donde dichos injertos están ligados por un espaciador formado en parte por al menos una función hidrolizable; procedimiento de preparación de dicho polímero; composición; y uso de nanopartículas de al menos dicho polímero.
CL2012001358A 2009-11-26 2012-05-25 Polimero con esqueleto lineal de tipo acrilico y/o metacrilico al que estan ligados injertos de alfa-tocoferol, por medio de un espaciador formado en parte por la menos una funcion hidroloizable yn porque el reparto de dichos injertos al nivel de dichos esqueleto es aleatorio; procedimiento de preparacion; composicion. CL2012001358A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0958413A FR2952936B1 (fr) 2009-11-26 2009-11-26 Polymere de type acrylique ou methacrylique comprenant des greffons alpha-tocopherol

Publications (1)

Publication Number Publication Date
CL2012001358A1 true CL2012001358A1 (es) 2012-10-12

Family

ID=42103880

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012001358A CL2012001358A1 (es) 2009-11-26 2012-05-25 Polimero con esqueleto lineal de tipo acrilico y/o metacrilico al que estan ligados injertos de alfa-tocoferol, por medio de un espaciador formado en parte por la menos una funcion hidroloizable yn porque el reparto de dichos injertos al nivel de dichos esqueleto es aleatorio; procedimiento de preparacion; composicion.

Country Status (13)

Country Link
US (1) US20110129540A1 (es)
EP (1) EP2504370A1 (es)
JP (1) JP2013512301A (es)
KR (1) KR20120099442A (es)
CN (1) CN102648221A (es)
AU (1) AU2010325556B2 (es)
CA (1) CA2781082A1 (es)
CL (1) CL2012001358A1 (es)
FR (1) FR2952936B1 (es)
IL (1) IL219491A0 (es)
MX (1) MX2012006042A (es)
WO (1) WO2011064743A1 (es)
ZA (1) ZA201203225B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2433248B1 (es) * 2012-05-07 2015-03-10 Consejo Superior Investigacion Copolimeros anfifilicos portadores de alfa-tocoferol con propiedades antitumorales
ES2721675B2 (es) * 2018-02-02 2020-02-06 Nanomateriales Y Polimeros S L Procedimiento de obtencion de particulas polimericas funcionalizadas
ES2735638B2 (es) * 2018-06-18 2021-01-18 Alodia Farm S L Copolimeros y terpolimeros acrilicos funcionales autoasociados y su uso como vehiculos de compuestos bioactivos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2680749A (en) * 1951-12-01 1954-06-08 Eastman Kodak Co Water-soluble tocopherol derivatives
US6123928A (en) * 1992-12-21 2000-09-26 Biophysica, Inc. Sunblocking polymers and their novel formulations
KR100195291B1 (ko) 1997-07-12 1999-06-15 서경배 비이온성 비타민
FR2786098B1 (fr) * 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
FR2830447B1 (fr) 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
CN101160118A (zh) * 2005-02-24 2008-04-09 依兰药物国际有限公司 多西紫杉醇或其类似物的纳米微粒制剂
EP2066406A2 (de) * 2006-09-19 2009-06-10 Basf Se Kosmetische zubereitungen auf basis molekular geprägter polymere
US20110150837A1 (en) * 2009-12-23 2011-06-23 Flamel Technologies Amphiphilic polymer functionalized by methionine

Also Published As

Publication number Publication date
AU2010325556B2 (en) 2013-07-11
US20110129540A1 (en) 2011-06-02
FR2952936A1 (fr) 2011-05-27
FR2952936B1 (fr) 2011-11-25
CN102648221A (zh) 2012-08-22
EP2504370A1 (fr) 2012-10-03
IL219491A0 (en) 2012-06-28
MX2012006042A (es) 2012-10-03
WO2011064743A1 (fr) 2011-06-03
CA2781082A1 (fr) 2011-06-03
KR20120099442A (ko) 2012-09-10
AU2010325556A1 (en) 2012-05-24
ZA201203225B (en) 2013-01-30
JP2013512301A (ja) 2013-04-11

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