CL2012001006A1 - Formulacion oftalmica para aplicar topica que comprende a) una suspension acuosa de una particula fina de un agonista a1, b) un agente tensioactivo y c) un conservante; proceso para prepararla; y un metodo para reducir la presion intraocular que comprende aplicar dicha formulacion. - Google Patents
Formulacion oftalmica para aplicar topica que comprende a) una suspension acuosa de una particula fina de un agonista a1, b) un agente tensioactivo y c) un conservante; proceso para prepararla; y un metodo para reducir la presion intraocular que comprende aplicar dicha formulacion.Info
- Publication number
- CL2012001006A1 CL2012001006A1 CL2012001006A CL2012001006A CL2012001006A1 CL 2012001006 A1 CL2012001006 A1 CL 2012001006A1 CL 2012001006 A CL2012001006 A CL 2012001006A CL 2012001006 A CL2012001006 A CL 2012001006A CL 2012001006 A1 CL2012001006 A1 CL 2012001006A1
- Authority
- CL
- Chile
- Prior art keywords
- formulation
- agonist
- preservative
- surfactant
- prepare
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25492309P | 2009-10-26 | 2009-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012001006A1 true CL2012001006A1 (es) | 2012-09-14 |
Family
ID=43922488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012001006A CL2012001006A1 (es) | 2009-10-26 | 2012-04-20 | Formulacion oftalmica para aplicar topica que comprende a) una suspension acuosa de una particula fina de un agonista a1, b) un agente tensioactivo y c) un conservante; proceso para prepararla; y un metodo para reducir la presion intraocular que comprende aplicar dicha formulacion. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20110123622A1 (es) |
EP (1) | EP2493480A4 (es) |
JP (1) | JP2013508420A (es) |
KR (1) | KR20120091049A (es) |
CN (1) | CN102665730A (es) |
AU (1) | AU2010313544A1 (es) |
BR (1) | BR112012009841A2 (es) |
CA (1) | CA2774704A1 (es) |
CL (1) | CL2012001006A1 (es) |
CO (1) | CO6531473A2 (es) |
EA (1) | EA201200635A1 (es) |
IL (1) | IL219225A0 (es) |
MX (1) | MX2012004225A (es) |
WO (1) | WO2011053569A1 (es) |
ZA (1) | ZA201202892B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI1009971A2 (pt) * | 2009-05-01 | 2016-03-15 | Inoteck Pharmaceuticals Corp | método de redução da pressão intraocular em humanos |
SG10201502588UA (en) | 2010-01-11 | 2015-05-28 | Inotek Pharmaceuticals Corp | Combination, kit and method of reducing intraocular pressure |
JP2013523739A (ja) * | 2010-03-26 | 2013-06-17 | イノテック ファーマシューティカルズ コーポレイション | N6−シクロペンチルアデノシン(cpa)、cpa誘導体またはそれらのプロドラッグを用いてヒトにおける眼内圧を低下させる方法 |
SG11201403979TA (en) * | 2012-01-26 | 2014-08-28 | Inotek Pharmaceuticals Corp | Anhydrous polymorphs of (2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl) } methyl nitrate and processes of preparation thereof |
EP2968389A4 (en) * | 2013-03-15 | 2016-08-24 | Inotek Pharmaceuticals Corp | OPHTHALMIC FORMULATIONS |
CA2902888A1 (en) * | 2013-03-15 | 2014-09-25 | Inotek Pharmaceuticals Corporation | A method of providing ocular neuroprotection |
WO2016090005A1 (en) * | 2014-12-03 | 2016-06-09 | Inotek Pharmaceuticals Corporation | Methods of preventing, reducing or treating macular degeneration |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4396625A (en) * | 1980-05-13 | 1983-08-02 | Sumitomo Chemical Company, Limited | Treatment of glaucoma or ocular hypertension and ophthalmic composition |
WO1996003158A1 (en) * | 1994-07-22 | 1996-02-08 | Alcon Laboratories, Inc. | Use of low molecular weight amino acids in ophthalmic compositions |
JP2002173427A (ja) * | 1998-09-01 | 2002-06-21 | Yamasa Shoyu Co Ltd | 眼疾患治療用医薬組成物 |
EP2221307A1 (en) * | 2004-05-26 | 2010-08-25 | Inotek Pharmaceuticals Corporation | Purine derivatives as adenosine A1 receptor agonists and methods of use thereof |
CA2627319A1 (en) * | 2005-11-30 | 2007-06-07 | Prakash Jagtap | Purine derivatives and methods of use thereof |
MX2008012185A (es) * | 2006-03-23 | 2008-10-02 | Inotek Pharmaceuticals Corp | Compuestos de purina y metodos de uso de los mismos. |
CN101404883A (zh) * | 2006-03-23 | 2009-04-08 | 伊诺泰克制药公司 | 嘌呤化合物及其用法 |
BRPI1009971A2 (pt) * | 2009-05-01 | 2016-03-15 | Inoteck Pharmaceuticals Corp | método de redução da pressão intraocular em humanos |
-
2010
- 2010-10-26 CA CA2774704A patent/CA2774704A1/en not_active Abandoned
- 2010-10-26 CN CN2010800485106A patent/CN102665730A/zh active Pending
- 2010-10-26 MX MX2012004225A patent/MX2012004225A/es not_active Application Discontinuation
- 2010-10-26 EP EP10827379.8A patent/EP2493480A4/en not_active Withdrawn
- 2010-10-26 KR KR1020127008520A patent/KR20120091049A/ko not_active Application Discontinuation
- 2010-10-26 US US12/912,054 patent/US20110123622A1/en not_active Abandoned
- 2010-10-26 BR BR112012009841A patent/BR112012009841A2/pt not_active IP Right Cessation
- 2010-10-26 JP JP2012535453A patent/JP2013508420A/ja active Pending
- 2010-10-26 EA EA201200635A patent/EA201200635A1/ru unknown
- 2010-10-26 AU AU2010313544A patent/AU2010313544A1/en not_active Abandoned
- 2010-10-26 WO PCT/US2010/054040 patent/WO2011053569A1/en active Application Filing
-
2012
- 2012-04-17 IL IL219225A patent/IL219225A0/en unknown
- 2012-04-19 ZA ZA2012/02892A patent/ZA201202892B/en unknown
- 2012-04-20 CL CL2012001006A patent/CL2012001006A1/es unknown
- 2012-04-25 CO CO12067890A patent/CO6531473A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL219225A0 (en) | 2012-06-28 |
EA201200635A1 (ru) | 2012-10-30 |
ZA201202892B (en) | 2014-10-29 |
US20110123622A1 (en) | 2011-05-26 |
CO6531473A2 (es) | 2012-09-28 |
WO2011053569A1 (en) | 2011-05-05 |
EP2493480A4 (en) | 2013-04-10 |
AU2010313544A1 (en) | 2012-05-10 |
EP2493480A1 (en) | 2012-09-05 |
CA2774704A1 (en) | 2011-05-05 |
KR20120091049A (ko) | 2012-08-17 |
JP2013508420A (ja) | 2013-03-07 |
BR112012009841A2 (pt) | 2016-11-29 |
CN102665730A (zh) | 2012-09-12 |
MX2012004225A (es) | 2012-06-08 |
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