CL2012000428A1 - Uso de un aerosol de una solucion de levofloxacina u ofloxacina para reducir la tasa de exacerbaciones agudas de un transtorno pulmonar seleccionado de epoc y bronquitis cronica. - Google Patents
Uso de un aerosol de una solucion de levofloxacina u ofloxacina para reducir la tasa de exacerbaciones agudas de un transtorno pulmonar seleccionado de epoc y bronquitis cronica.Info
- Publication number
- CL2012000428A1 CL2012000428A1 CL2012000428A CL2012000428A CL2012000428A1 CL 2012000428 A1 CL2012000428 A1 CL 2012000428A1 CL 2012000428 A CL2012000428 A CL 2012000428A CL 2012000428 A CL2012000428 A CL 2012000428A CL 2012000428 A1 CL2012000428 A1 CL 2012000428A1
- Authority
- CL
- Chile
- Prior art keywords
- levofloxacin
- ofloxacin
- copd
- rate
- solution
- Prior art date
Links
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 title abstract 2
- 206010006458 Bronchitis chronic Diseases 0.000 title abstract 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title abstract 2
- GSDSWSVVBLHKDQ-JTQLQIEISA-N Levofloxacin Chemical compound C([C@@H](N1C2=C(C(C(C(O)=O)=C1)=O)C=C1F)C)OC2=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-JTQLQIEISA-N 0.000 title abstract 2
- 208000019693 Lung disease Diseases 0.000 title abstract 2
- 230000009798 acute exacerbation Effects 0.000 title abstract 2
- 239000000443 aerosol Substances 0.000 title abstract 2
- 206010006451 bronchitis Diseases 0.000 title abstract 2
- 208000007451 chronic bronchitis Diseases 0.000 title abstract 2
- 229960003376 levofloxacin Drugs 0.000 title abstract 2
- 229960001699 ofloxacin Drugs 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Método para reducir la tasa de exacerbaciones agudas de un trastorno pulmonar seleccionado de epoc y bronquitis crónica por medio de la administración en aerosol de una solución de levofloxacino u ofloxacino
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23531909P | 2009-08-19 | 2009-08-19 | |
US24074909P | 2009-09-09 | 2009-09-09 | |
US24922809P | 2009-10-06 | 2009-10-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012000428A1 true CL2012000428A1 (es) | 2012-09-28 |
Family
ID=43607264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012000428A CL2012000428A1 (es) | 2009-08-19 | 2012-02-17 | Uso de un aerosol de una solucion de levofloxacina u ofloxacina para reducir la tasa de exacerbaciones agudas de un transtorno pulmonar seleccionado de epoc y bronquitis cronica. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20120237564A1 (es) |
EP (1) | EP2467138A4 (es) |
JP (1) | JP2013502416A (es) |
KR (1) | KR20120103561A (es) |
CN (1) | CN102711760A (es) |
AU (1) | AU2010284678A1 (es) |
BR (1) | BR112012003453A2 (es) |
CA (1) | CA2770355A1 (es) |
CL (1) | CL2012000428A1 (es) |
IL (1) | IL218148A0 (es) |
MX (1) | MX2012002091A (es) |
RU (1) | RU2012108962A (es) |
WO (1) | WO2011022075A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8546423B2 (en) | 2005-05-18 | 2013-10-01 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
NZ592717A (en) * | 2008-10-07 | 2013-03-28 | Mpex Pharmaceuticals Inc | Aerosol fluoroquinolone formulations for improved pharmacokinetics comprising levofloxacin or ofloxacin and a di- or trivalent cation |
PT2346509T (pt) | 2008-10-07 | 2020-08-05 | Horizon Orphan Llc | Inalação de levofloxacina para redução da inflamação pulmonar |
RU2563809C2 (ru) | 2009-09-04 | 2015-09-20 | Мпекс Фармасьютикалс, Инк. | Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза |
US20160068527A1 (en) * | 2013-04-09 | 2016-03-10 | Cresset Biomolecular Discovery Ltd. | The Treatment of Inflammatory Disorders |
CA3109823A1 (en) * | 2018-08-22 | 2020-02-27 | Avalyn Pharma Inc. | Specially formulated compositions of inhaled nintedanib and nintedanib salts |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1901749T3 (en) * | 2005-05-18 | 2016-10-24 | Raptor Pharmaceuticals Inc | Aerosolized fluoroquinolones AND USES THEREOF |
US7838532B2 (en) * | 2005-05-18 | 2010-11-23 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
RU2008136460A (ru) * | 2006-02-10 | 2010-03-20 | Пари Фарма ГмбХ (DE) | Фармацевтический аэрозоль |
NZ592717A (en) * | 2008-10-07 | 2013-03-28 | Mpex Pharmaceuticals Inc | Aerosol fluoroquinolone formulations for improved pharmacokinetics comprising levofloxacin or ofloxacin and a di- or trivalent cation |
PT2346509T (pt) * | 2008-10-07 | 2020-08-05 | Horizon Orphan Llc | Inalação de levofloxacina para redução da inflamação pulmonar |
-
2010
- 2010-08-19 RU RU2012108962/15A patent/RU2012108962A/ru not_active Application Discontinuation
- 2010-08-19 BR BR112012003453A patent/BR112012003453A2/pt not_active IP Right Cessation
- 2010-08-19 EP EP10810291.4A patent/EP2467138A4/en not_active Withdrawn
- 2010-08-19 MX MX2012002091A patent/MX2012002091A/es not_active Application Discontinuation
- 2010-08-19 WO PCT/US2010/002307 patent/WO2011022075A1/en active Application Filing
- 2010-08-19 JP JP2012525534A patent/JP2013502416A/ja active Pending
- 2010-08-19 AU AU2010284678A patent/AU2010284678A1/en not_active Abandoned
- 2010-08-19 CN CN2010800416695A patent/CN102711760A/zh active Pending
- 2010-08-19 CA CA2770355A patent/CA2770355A1/en not_active Abandoned
- 2010-08-19 KR KR1020127006930A patent/KR20120103561A/ko not_active Application Discontinuation
-
2012
- 2012-02-16 IL IL218148A patent/IL218148A0/en unknown
- 2012-02-16 US US13/398,310 patent/US20120237564A1/en not_active Abandoned
- 2012-02-17 CL CL2012000428A patent/CL2012000428A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20120103561A (ko) | 2012-09-19 |
IL218148A0 (en) | 2012-06-28 |
WO2011022075A1 (en) | 2011-02-24 |
CA2770355A1 (en) | 2011-02-24 |
AU2010284678A1 (en) | 2012-02-23 |
CN102711760A (zh) | 2012-10-03 |
JP2013502416A (ja) | 2013-01-24 |
BR112012003453A2 (pt) | 2019-09-24 |
US20120237564A1 (en) | 2012-09-20 |
EP2467138A1 (en) | 2012-06-27 |
MX2012002091A (es) | 2012-07-03 |
RU2012108962A (ru) | 2013-09-27 |
EP2467138A4 (en) | 2013-11-06 |
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