CL2011003094A1 - Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv. - Google Patents
Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv.Info
- Publication number
- CL2011003094A1 CL2011003094A1 CL2011003094A CL2011003094A CL2011003094A1 CL 2011003094 A1 CL2011003094 A1 CL 2011003094A1 CL 2011003094 A CL2011003094 A CL 2011003094A CL 2011003094 A CL2011003094 A CL 2011003094A CL 2011003094 A1 CL2011003094 A1 CL 2011003094A1
- Authority
- CL
- Chile
- Prior art keywords
- cancerous
- ala
- hpv
- triglycerides
- cancer
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Gynecology & Obstetrics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09251537 | 2009-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011003094A1 true CL2011003094A1 (es) | 2012-07-20 |
Family
ID=41213323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011003094A CL2011003094A1 (es) | 2009-06-11 | 2011-12-06 | Composicion farmaceutica semi-solida libre de agua que comprende a) un ester del acido 5-aminolevulinico (5-ala) o una sal del mismo, b) uno o mas trigliceridos y c) opcionalmente uno o mas potenciadores de viscosidad; kit farmaceutico; y su uso en el tratamiento fotodinamico del cancer, condiciones pre-cancerosas y no cancerosas asociadas a hpv. |
Country Status (21)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8992954B2 (en) * | 2010-03-01 | 2015-03-31 | Photocure Asa | Compositions comprising a derivative of 5-aminolevulinic acid |
| EP2590714B1 (en) | 2010-07-09 | 2017-03-08 | Photocure ASA | Devices containing dry compositions for use in photodynamic therapy |
| JP2015500717A (ja) | 2011-12-19 | 2015-01-08 | フォトキュア エイエスエイ | 照射装置 |
| CN102670577B (zh) * | 2012-05-18 | 2018-04-13 | 上海复旦张江生物医药股份有限公司 | 一种光敏剂组合物、其使用方法及用途 |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| JP6363115B2 (ja) | 2013-02-28 | 2018-07-25 | ミラ ファーマ コーポレイション | 注射可能局所麻酔半固体製剤およびその組成物 |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
| US9943576B2 (en) * | 2014-04-30 | 2018-04-17 | Allergan, Inc. | Formulations of biologics for intravesical instillation |
| CZ307444B6 (cs) * | 2015-04-22 | 2018-08-29 | Jakub Rak | Mukoadhezivní polymerní film pro fotosenzitivní terapii v ústní dutině s obsahem fotosenzitizérů |
| KR20180094986A (ko) | 2015-12-17 | 2018-08-24 | 포토큐어 에이에스에이 | 방광암에 대한 광역학 요법 (pdt)의 방법 |
| GB201522309D0 (en) | 2015-12-17 | 2016-02-03 | Photocure Asa | Use |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| HUE054241T2 (hu) * | 2016-03-28 | 2021-08-30 | Vidac Pharma Ltd | Stabil gyógyszerkészítmények topikális beadásra és alkalmazásuk |
| US11884784B2 (en) | 2016-05-10 | 2024-01-30 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| US11039616B2 (en) | 2016-05-10 | 2021-06-22 | North Carolina State University | Photodynamic compositions, methods of making, and uses thereof |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| EP4299395A1 (en) * | 2017-05-01 | 2024-01-03 | Cummins, Inc. | Systems and methods for controlling energy generation in a hybrid powertrain |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| GB201808571D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| JP7474773B2 (ja) | 2019-02-13 | 2024-04-25 | アルフェウス メディカル，インク． | 非侵襲的音響化学療法 |
| CN110575612A (zh) * | 2019-09-27 | 2019-12-17 | 赵志国 | 女用光动力凝胶封包敷料装置 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| JPH08175986A (ja) * | 1994-09-20 | 1996-07-09 | Johnson & Johnson Medical Inc | 経皮活性を示す５−アミノレブリン酸含有薬学組成物 |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| ATE202076T1 (de) | 1995-03-10 | 2001-06-15 | Photocure Asa | Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie |
| JP2000502044A (ja) * | 1995-08-14 | 2000-02-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 緑色ポルフィリンを用いた光力学療法による子宮内膜の切除 |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| US20020132035A1 (en) * | 2001-01-10 | 2002-09-19 | Dov Tamarkin | Synthetic fat composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0118251D0 (en) | 2001-07-26 | 2001-09-19 | Photocure Asa | Method |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| EP1312353A1 (en) | 2001-11-16 | 2003-05-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for hair removal |
| US20040009212A1 (en) * | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| CA2457214A1 (en) * | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| DE102005019628A1 (de) * | 2005-04-26 | 2006-11-09 | Technische Universität Braunschweig | Formulierung zur dermalen Anwendung |
| GB0700580D0 (en) * | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
-
2010
- 2010-06-11 ES ES16156371T patent/ES2821831T3/es active Active
- 2010-06-11 AU AU2010257753A patent/AU2010257753B2/en active Active
- 2010-06-11 SI SI201031166A patent/SI2440199T1/sl unknown
- 2010-06-11 NZ NZ596943A patent/NZ596943A/xx unknown
- 2010-06-11 ES ES10724715.7T patent/ES2573085T3/es active Active
- 2010-06-11 SG SG2011090057A patent/SG176688A1/en unknown
- 2010-06-11 DK DK10724715.7T patent/DK2440199T3/en active
- 2010-06-11 KR KR1020127000600A patent/KR101797780B1/ko active IP Right Grant
- 2010-06-11 EP EP10724715.7A patent/EP2440199B1/en not_active Not-in-force
- 2010-06-11 PL PL10724715.7T patent/PL2440199T3/pl unknown
- 2010-06-11 JP JP2012514393A patent/JP5840604B2/ja active Active
- 2010-06-11 CA CA2763923A patent/CA2763923C/en active Active
- 2010-06-11 BR BRPI1010761A patent/BRPI1010761A2/pt not_active Application Discontinuation
- 2010-06-11 US US13/377,722 patent/US20120136055A1/en not_active Abandoned
- 2010-06-11 MX MX2011013127A patent/MX2011013127A/es unknown
- 2010-06-11 WO PCT/EP2010/003532 patent/WO2010142457A1/en active Application Filing
- 2010-06-11 HU HUE10724715A patent/HUE026911T2/en unknown
- 2010-06-11 EP EP16156371.3A patent/EP3042647B1/en active Active
- 2010-06-11 RU RU2011150919/15A patent/RU2526803C2/ru active
- 2010-06-11 CN CN201080025639.5A patent/CN102458388B/zh active Active
- 2010-06-11 KR KR1020177027346A patent/KR20170116198A/ko not_active Application Discontinuation
-
2011
- 2011-12-06 CL CL2011003094A patent/CL2011003094A1/es unknown
- 2011-12-12 ZA ZA2011/09126A patent/ZA201109126B/en unknown
-
2012
- 2012-05-25 HK HK12105140.4A patent/HK1164163A1/zh unknown
-
2015
- 2015-05-08 US US14/707,639 patent/US9326964B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150238457A1 (en) | 2015-08-27 |
| DK2440199T3 (en) | 2016-05-17 |
| RU2526803C2 (ru) | 2014-08-27 |
| EP3042647A1 (en) | 2016-07-13 |
| PL2440199T3 (pl) | 2016-10-31 |
| CA2763923C (en) | 2016-09-13 |
| RU2011150919A (ru) | 2013-07-20 |
| KR20170116198A (ko) | 2017-10-18 |
| CN102458388A (zh) | 2012-05-16 |
| US20120136055A1 (en) | 2012-05-31 |
| CN102458388B (zh) | 2016-09-28 |
| EP2440199B1 (en) | 2016-04-13 |
| WO2010142457A1 (en) | 2010-12-16 |
| HUE026911T2 (en) | 2016-07-28 |
| EP2440199A1 (en) | 2012-04-18 |
| SI2440199T1 (sl) | 2016-05-31 |
| ZA201109126B (en) | 2013-02-27 |
| AU2010257753A1 (en) | 2012-01-12 |
| US9326964B2 (en) | 2016-05-03 |
| HK1164163A1 (zh) | 2012-09-21 |
| KR20120046155A (ko) | 2012-05-09 |
| ES2821831T3 (es) | 2021-04-27 |
| NZ596943A (en) | 2013-09-27 |
| JP5840604B2 (ja) | 2016-01-06 |
| ES2573085T3 (es) | 2016-06-06 |
| JP2012529452A (ja) | 2012-11-22 |
| EP3042647B1 (en) | 2020-08-26 |
| SG176688A1 (en) | 2012-01-30 |
| AU2010257753B2 (en) | 2014-09-18 |
| BRPI1010761A2 (pt) | 2016-03-22 |
| CA2763923A1 (en) | 2010-12-16 |
| MX2011013127A (es) | 2012-02-21 |
| KR101797780B1 (ko) | 2017-11-14 |
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