CL2011000380A1 - Granulo para ser utilizado en la braquiterapia, que comprende una estructura insoluble o coloidal con radioisotopo, una matriz de polimero reabsorbible, que a su vez comprende particulas individuales, consistentes en sorbitol cubierto con un polimero biodegradable; y metodo para la fabricacion de dichos granulos. - Google Patents
Granulo para ser utilizado en la braquiterapia, que comprende una estructura insoluble o coloidal con radioisotopo, una matriz de polimero reabsorbible, que a su vez comprende particulas individuales, consistentes en sorbitol cubierto con un polimero biodegradable; y metodo para la fabricacion de dichos granulos.Info
- Publication number
- CL2011000380A1 CL2011000380A1 CL2011000380A CL2011000380A CL2011000380A1 CL 2011000380 A1 CL2011000380 A1 CL 2011000380A1 CL 2011000380 A CL2011000380 A CL 2011000380A CL 2011000380 A CL2011000380 A CL 2011000380A CL 2011000380 A1 CL2011000380 A1 CL 2011000380A1
- Authority
- CL
- Chile
- Prior art keywords
- insoluble
- radioisotope
- granule
- brachytherapy
- granules
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
- A61K51/1251—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/80—Component parts, details or accessories; Auxiliary operations
- B29B7/88—Adding charges, i.e. additives
- B29B7/94—Liquid charges
- B29B7/945—Liquid charges involving coating particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/003—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/027—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles having an axis of symmetry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N2005/1019—Sources therefor
- A61N2005/1024—Seeds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/1087—Ions; Protons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/1089—Electrons
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B9/00—Making granules
- B29B9/16—Auxiliary treatment of granules
- B29B2009/163—Coating, i.e. applying a layer of liquid or solid material on the granule
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
- B29K2067/04—Polyesters derived from hydroxycarboxylic acids
- B29K2067/046—PLA, i.e. polylactic acid or polylactide
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0059—Degradable
- B29K2995/006—Bio-degradable, e.g. bioabsorbable, bioresorbable or bioerodible
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Nanotechnology (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mechanical Engineering (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
EN LA PRESENTE INVENCIÓN SE PROVEE UN GRÁNULO PARA SER UTILIZADO EN LA BRAQUITERAPIA, QUE COMPRENDE UNA ESTRUCTURA INSOLUBLE O COLOIDAL QUE COMPRENDE UN RADIOISÓTOPO; UNA MATRIZ DE UN POLÍMERO REABSORBIBLE QUE TIENE LA ESTRUCTURA INSOLUBLE O COLOIDAL EN ELLA; Y DONDE LA MATRIZ DE UN POLÍMERO REABSORBIBLE COMPRENDE PARTÍCULAS INDIVIDUALES CONSISTENTES EN SORBITOL CUBIERTO CON POLÍMERO BIODEGRADABLE. LA INVENCIÓN PROVEE ADEMÁS UN MÉTODO PARA LA FABRICACIÓN DE GRÁNULOS PARA BRAQUITERAPIA QUE COMPRENDE LAS ETAPAS DE: PROVEER UNA ESTRUCTURA INSOLUBLE O COLOIDAL QUE COMPRENDE UN RADIOISÓTOPO; PROVEER UNA MEZCLA DE PARTÍCULAS, QUE SON PARTÍCULAS INDIVIDUALES QUE COMPRENDEN EN SORBITOL CUBIERTO CON POLÍMERO NATURAL; Y PRESIONAR LA MEZCLA DE PARTÍCULAS SOBRE LA ESTRUCTURA INSOLUBLE O COLOIDAL PARA FORMAR UN GRÁNULO DE BRAQUITERAPIA, EN DONDE EL GRÁNULO COMPRENDE LAS PARTÍCULAS QUE FORMAN UNA MATRIZ QUE COMPRENDE LA ESTRUCTURA INSOLUBLE O COLOIDAL.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/202,954 US20100056843A1 (en) | 2008-09-02 | 2008-09-02 | Brachytherapy Seed With Fast Dissolving Matrix for Optimal Delivery of Radionuclides To Cancer Tissue |
US12/552,190 US8821364B2 (en) | 2008-09-02 | 2009-09-01 | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
Publications (1)
Publication Number | Publication Date |
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CL2011000380A1 true CL2011000380A1 (es) | 2011-06-17 |
Family
ID=41319980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2011000380A CL2011000380A1 (es) | 2008-09-02 | 2011-02-22 | Granulo para ser utilizado en la braquiterapia, que comprende una estructura insoluble o coloidal con radioisotopo, una matriz de polimero reabsorbible, que a su vez comprende particulas individuales, consistentes en sorbitol cubierto con un polimero biodegradable; y metodo para la fabricacion de dichos granulos. |
Country Status (10)
Country | Link |
---|---|
US (3) | US8821364B2 (es) |
EP (1) | EP2331064B1 (es) |
KR (1) | KR101660061B1 (es) |
CN (1) | CN102202644A (es) |
BR (1) | BRPI0918594A2 (es) |
CA (1) | CA2733823C (es) |
CL (1) | CL2011000380A1 (es) |
CO (1) | CO6491121A2 (es) |
MX (1) | MX2011002095A (es) |
WO (1) | WO2010028048A1 (es) |
Families Citing this family (19)
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US8821364B2 (en) | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
JP6106259B2 (ja) * | 2012-03-21 | 2017-03-29 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 医用イメージングと生検データとを統合する臨床ワークステーション及びこれを使用する方法 |
GB2512384B (en) * | 2013-03-28 | 2016-07-20 | Elekta Ab | Markers, Phantoms and Associated Methods for Calibrating Imaging Systems |
CN103736200B (zh) * | 2013-12-31 | 2016-08-17 | 原子高科股份有限公司 | 一种放射性粒子链的制备方法 |
CN104436248B (zh) * | 2014-11-11 | 2016-12-21 | 成都维宁生物技术有限公司 | 装有放射性核素的微管及其制造方法及应用 |
DE102016119239A1 (de) * | 2016-10-10 | 2018-04-12 | Oncobeta International Gmbh | Partikel und Zusammensetzung, die Rheniumverbindungen umfassen, und Prozesse zum Erhalten solcher Produkte |
WO2018138744A1 (en) * | 2017-01-24 | 2018-08-02 | Maria Desantis | Composition, device and method for conformational intra-tissue beta branchytherapy |
MX2019013346A (es) * | 2017-05-11 | 2020-01-20 | Alpha Tau Medical Ltd | Recubrimientos polimericos para dispositivos de braquiterapia. |
EP3645058A4 (en) * | 2017-06-28 | 2021-05-12 | The Regents of The University of California | COMPOSITE EMBOLIZATION BEADS |
US10646727B2 (en) | 2017-11-13 | 2020-05-12 | Positive Energy, Llc | Anchored brachytherapy device |
CN108014414B (zh) * | 2018-01-05 | 2019-10-18 | 清华大学 | 一种植入式可降解药物缓释电子贴片的制备方法 |
JP2021519126A (ja) | 2018-04-02 | 2021-08-10 | アルファ タウ メディカル リミテッド | 放射性核種の管理された放出 |
CN110215600A (zh) * | 2019-05-27 | 2019-09-10 | 北京大学第三医院 | 可携带放射粒子的植入物 |
US11478557B2 (en) * | 2019-07-01 | 2022-10-25 | Vivos, Inc. | Method of preparing a radioactive yttrium phosphate particle suspension |
JP2022547277A (ja) | 2019-09-16 | 2022-11-11 | エービーケー バイオメディカル インコーポレイテッド | 放射性微粒子及び非放射性微粒子の組成物 |
CN111603575A (zh) * | 2020-02-28 | 2020-09-01 | 彭盛 | 一种核壳结构的放射栓塞微球及其制备方法与应用 |
AU2021400142A1 (en) | 2020-12-16 | 2023-06-22 | Alpha Tau Medical Ltd. | Diffusing alpha-emitters radiation therapy with enhanced beta treatment |
US11964168B2 (en) | 2021-06-10 | 2024-04-23 | Alpha Tau Medical Ltd. | Diffusing alpha-emitter radiation therapy for prostate cancer |
WO2024052886A1 (en) * | 2022-09-11 | 2024-03-14 | Alpha Tau Medical Ltd. | Radiotherapy sheet |
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US20080187998A1 (en) | 2007-02-01 | 2008-08-07 | University Of Utah Research Foundation | Sulfonamide-based oligomers and polymers for destabilization of biological membranes |
US8394391B2 (en) | 2007-08-31 | 2013-03-12 | University Of Utah Research Foundation | Drug delivery vehicle that mimics viral properties |
US8821364B2 (en) | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
-
2009
- 2009-09-01 US US12/552,190 patent/US8821364B2/en not_active Expired - Fee Related
- 2009-09-02 MX MX2011002095A patent/MX2011002095A/es active IP Right Grant
- 2009-09-02 CN CN2009801340864A patent/CN102202644A/zh active Pending
- 2009-09-02 KR KR1020117007638A patent/KR101660061B1/ko active IP Right Grant
- 2009-09-02 CA CA2733823A patent/CA2733823C/en not_active Expired - Fee Related
- 2009-09-02 BR BRPI0918594A patent/BRPI0918594A2/pt not_active IP Right Cessation
- 2009-09-02 WO PCT/US2009/055738 patent/WO2010028048A1/en active Application Filing
- 2009-09-02 EP EP09792174.6A patent/EP2331064B1/en active Active
-
2011
- 2011-02-22 CL CL2011000380A patent/CL2011000380A1/es unknown
- 2011-04-01 CO CO11040324A patent/CO6491121A2/es active IP Right Grant
-
2014
- 2014-08-07 US US14/454,605 patent/US9289625B2/en not_active Expired - Fee Related
-
2016
- 2016-03-14 US US15/069,801 patent/US20160193479A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2733823A1 (en) | 2010-03-11 |
MX2011002095A (es) | 2012-01-25 |
US8821364B2 (en) | 2014-09-02 |
US9289625B2 (en) | 2016-03-22 |
KR101660061B1 (ko) | 2016-09-30 |
CN102202644A (zh) | 2011-09-28 |
EP2331064A1 (en) | 2011-06-15 |
KR20110054036A (ko) | 2011-05-24 |
CA2733823C (en) | 2015-02-17 |
CO6491121A2 (es) | 2012-07-31 |
EP2331064B1 (en) | 2013-08-28 |
US20100056844A1 (en) | 2010-03-04 |
US20140350326A1 (en) | 2014-11-27 |
WO2010028048A1 (en) | 2010-03-11 |
BRPI0918594A2 (pt) | 2018-01-30 |
US20160193479A1 (en) | 2016-07-07 |
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