CL2008001913A1 - Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito. - Google Patents
Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito.Info
- Publication number
- CL2008001913A1 CL2008001913A1 CL2008001913A CL2008001913A CL2008001913A1 CL 2008001913 A1 CL2008001913 A1 CL 2008001913A1 CL 2008001913 A CL2008001913 A CL 2008001913A CL 2008001913 A CL2008001913 A CL 2008001913A CL 2008001913 A1 CL2008001913 A1 CL 2008001913A1
- Authority
- CL
- Chile
- Prior art keywords
- methoxypyrimidin
- dichlorophenyl
- ethylamino
- phenyl
- methyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- -1 3- {6- [2- (2,4-dichlorophenyl) -ethylamino] -2-methoxypyrimidin-4-yl} -phenyl Chemical group 0.000 title 1
- FJKKCRCBBAXLQZ-UHFFFAOYSA-N 2-[3-[6-[2-(2,4-dichlorophenyl)ethylamino]-2-methoxypyrimidin-4-yl]phenyl]-2-methylpropanoic acid Chemical compound C=1C(C=2C=C(C=CC=2)C(C)(C)C(O)=O)=NC(OC)=NC=1NCCC1=CC=C(Cl)C=C1Cl FJKKCRCBBAXLQZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94725607P | 2007-06-29 | 2007-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008001913A1 true CL2008001913A1 (es) | 2009-01-16 |
Family
ID=40226759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2008001913A CL2008001913A1 (es) | 2007-06-29 | 2008-06-27 | Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100184979A1 (enExample) |
| EP (1) | EP2170837B1 (enExample) |
| JP (1) | JP2010532366A (enExample) |
| AR (1) | AR067348A1 (enExample) |
| AT (1) | ATE531699T1 (enExample) |
| CL (1) | CL2008001913A1 (enExample) |
| PA (1) | PA8786301A1 (enExample) |
| PE (1) | PE20090428A1 (enExample) |
| TW (1) | TW200922927A (enExample) |
| UY (1) | UY31192A1 (enExample) |
| WO (1) | WO2009006086A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5833626B2 (ja) * | 2010-03-23 | 2015-12-16 | サイノファーム タイワン リミテッド | ラパチニブの調製プロセス及び中間体 |
| CN104592137B (zh) * | 2014-11-04 | 2016-09-14 | 江苏大学 | 2,2’,2”-[1,3,5-三嗪-2,4,6-三巯基]三丙酸及其合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN2005000795A (es) | 2004-10-15 | 2010-08-19 | Aventis Pharma Inc | Pirimidinas como antagonistas del receptor de prostaglandina d2 |
| GT200600457A (es) * | 2005-10-13 | 2007-04-27 | Aventis Pharma Inc | Sal de fosfato dihidrogeno como antagonistas del receptor de prostaglandina d2 |
| AR074776A1 (es) * | 2008-12-18 | 2011-02-09 | Sanofi Aventis | Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente |
-
2008
- 2008-06-24 JP JP2010515021A patent/JP2010532366A/ja not_active Abandoned
- 2008-06-24 WO PCT/US2008/067963 patent/WO2009006086A2/en not_active Ceased
- 2008-06-24 EP EP08771774A patent/EP2170837B1/en not_active Not-in-force
- 2008-06-24 AT AT08771774T patent/ATE531699T1/de active
- 2008-06-27 PE PE2008001109A patent/PE20090428A1/es not_active Application Discontinuation
- 2008-06-27 PA PA20088786301A patent/PA8786301A1/es unknown
- 2008-06-27 UY UY31192A patent/UY31192A1/es not_active Application Discontinuation
- 2008-06-27 AR ARP080102795A patent/AR067348A1/es not_active Application Discontinuation
- 2008-06-27 CL CL2008001913A patent/CL2008001913A1/es unknown
- 2008-06-27 TW TW097124002A patent/TW200922927A/zh unknown
-
2009
- 2009-12-16 US US12/639,507 patent/US20100184979A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PA8786301A1 (es) | 2009-01-23 |
| EP2170837B1 (en) | 2011-11-02 |
| JP2010532366A (ja) | 2010-10-07 |
| EP2170837A2 (en) | 2010-04-07 |
| US20100184979A1 (en) | 2010-07-22 |
| TW200922927A (en) | 2009-06-01 |
| WO2009006086A3 (en) | 2009-03-12 |
| ATE531699T1 (de) | 2011-11-15 |
| UY31192A1 (es) | 2009-01-30 |
| PE20090428A1 (es) | 2009-05-04 |
| AR067348A1 (es) | 2009-10-07 |
| WO2009006086A2 (en) | 2009-01-08 |
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