CL2008001913A1 - Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito. - Google Patents

Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito.

Info

Publication number
CL2008001913A1
CL2008001913A1 CL2008001913A CL2008001913A CL2008001913A1 CL 2008001913 A1 CL2008001913 A1 CL 2008001913A1 CL 2008001913 A CL2008001913 A CL 2008001913A CL 2008001913 A CL2008001913 A CL 2008001913A CL 2008001913 A1 CL2008001913 A1 CL 2008001913A1
Authority
CL
Chile
Prior art keywords
methoxypyrimidin
dichlorophenyl
ethylamino
phenyl
methyl
Prior art date
Application number
CL2008001913A
Other languages
English (en)
Inventor
Bao-Guo Huang
Reda G Hanna
Elizabeth Secord
Matthew R Powers
Original Assignee
Sanoofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanoofi Aventis filed Critical Sanoofi Aventis
Publication of CL2008001913A1 publication Critical patent/CL2008001913A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedimiento para preparar ácido 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propiónico; y compuestos intermediarios.
CL2008001913A 2007-06-29 2008-06-27 Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito. CL2008001913A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94725607P 2007-06-29 2007-06-29

Publications (1)

Publication Number Publication Date
CL2008001913A1 true CL2008001913A1 (es) 2009-01-16

Family

ID=40226759

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008001913A CL2008001913A1 (es) 2007-06-29 2008-06-27 Procedimiento de prepararaciacin 2-(3-{6-[2-(2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propionico; y uno de los compuestos intermediarios usado el procedimiento descrito.

Country Status (11)

Country Link
US (1) US20100184979A1 (es)
EP (1) EP2170837B1 (es)
JP (1) JP2010532366A (es)
AR (1) AR067348A1 (es)
AT (1) ATE531699T1 (es)
CL (1) CL2008001913A1 (es)
PA (1) PA8786301A1 (es)
PE (1) PE20090428A1 (es)
TW (1) TW200922927A (es)
UY (1) UY31192A1 (es)
WO (1) WO2009006086A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5833626B2 (ja) * 2010-03-23 2015-12-16 サイノファーム タイワン リミテッド ラパチニブの調製プロセス及び中間体
CN104592137B (zh) * 2014-11-04 2016-09-14 江苏大学 2,2’,2”-[1,3,5-三嗪-2,4,6-三巯基]三丙酸及其合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT200500284A (es) 2004-10-15 2006-03-27 Aventis Pharma Inc Pirimidinas como antagonistas del receptor de prostaglandina d2
GT200600457A (es) * 2005-10-13 2007-04-27 Aventis Pharma Inc Sal de fosfato dihidrogeno como antagonistas del receptor de prostaglandina d2
AR074776A1 (es) * 2008-12-18 2011-02-09 Sanofi Aventis Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente

Also Published As

Publication number Publication date
TW200922927A (en) 2009-06-01
JP2010532366A (ja) 2010-10-07
ATE531699T1 (de) 2011-11-15
EP2170837A2 (en) 2010-04-07
EP2170837B1 (en) 2011-11-02
AR067348A1 (es) 2009-10-07
WO2009006086A2 (en) 2009-01-08
PE20090428A1 (es) 2009-05-04
PA8786301A1 (es) 2009-01-23
UY31192A1 (es) 2009-01-30
WO2009006086A3 (en) 2009-03-12
US20100184979A1 (en) 2010-07-22

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