CL2008001136A1 - Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5-(metoxi)piridin-2-carboxamida, en forma de hidrato, solvato, base o sal de adicion a un acido, para preparar un medicamento util en el tratamiento de trastornos motores asociados a la enfermedad de parkinson, tales como, bradiquinesia, discapacidad al caminar y disfagia. - Google Patents

Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5-(metoxi)piridin-2-carboxamida, en forma de hidrato, solvato, base o sal de adicion a un acido, para preparar un medicamento util en el tratamiento de trastornos motores asociados a la enfermedad de parkinson, tales como, bradiquinesia, discapacidad al caminar y disfagia.

Info

Publication number
CL2008001136A1
CL2008001136A1 CL2008001136A CL2008001136A CL2008001136A1 CL 2008001136 A1 CL2008001136 A1 CL 2008001136A1 CL 2008001136 A CL2008001136 A CL 2008001136A CL 2008001136 A CL2008001136 A CL 2008001136A CL 2008001136 A1 CL2008001136 A1 CL 2008001136A1
Authority
CL
Chile
Prior art keywords
pyridin
bradykinesia
dysphagia
oxido
carboxamide
Prior art date
Application number
CL2008001136A
Other languages
English (en)
Spanish (es)
Inventor
Philippe Delay-Goyet
Trillou Christine Ravinet
Claire Delgorge
Gilles Poughon
Christine Menet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CL2008001136A1 publication Critical patent/CL2008001136A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CL2008001136A 2007-04-19 2008-04-18 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5-(metoxi)piridin-2-carboxamida, en forma de hidrato, solvato, base o sal de adicion a un acido, para preparar un medicamento util en el tratamiento de trastornos motores asociados a la enfermedad de parkinson, tales como, bradiquinesia, discapacidad al caminar y disfagia. CL2008001136A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702853A FR2915100B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxalide pour le traitement des desordres moteurs lies a la maladie de parkinson

Publications (1)

Publication Number Publication Date
CL2008001136A1 true CL2008001136A1 (es) 2009-01-16

Family

ID=38712405

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008001136A CL2008001136A1 (es) 2007-04-19 2008-04-18 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5-(metoxi)piridin-2-carboxamida, en forma de hidrato, solvato, base o sal de adicion a un acido, para preparar un medicamento util en el tratamiento de trastornos motores asociados a la enfermedad de parkinson, tales como, bradiquinesia, discapacidad al caminar y disfagia.

Country Status (33)

Country Link
US (1) US20100130554A1 (enExample)
EP (1) EP2146714B1 (enExample)
JP (1) JP5386478B2 (enExample)
KR (2) KR20150004885A (enExample)
CN (1) CN101663035B (enExample)
AR (1) AR066108A1 (enExample)
AT (1) ATE513548T1 (enExample)
AU (1) AU2008257322B2 (enExample)
BR (1) BRPI0810444A2 (enExample)
CA (1) CA2684174C (enExample)
CL (1) CL2008001136A1 (enExample)
CY (1) CY1111840T1 (enExample)
DK (1) DK2146714T3 (enExample)
EA (1) EA019194B1 (enExample)
ES (1) ES2367408T3 (enExample)
FR (1) FR2915100B1 (enExample)
HR (1) HRP20110666T1 (enExample)
IL (1) IL201448A (enExample)
JO (1) JO2678B1 (enExample)
MA (1) MA31367B1 (enExample)
ME (1) ME00935B (enExample)
MX (1) MX2009011284A (enExample)
MY (1) MY148092A (enExample)
NZ (1) NZ580482A (enExample)
PA (1) PA8776801A1 (enExample)
PL (1) PL2146714T3 (enExample)
PT (1) PT2146714E (enExample)
RS (1) RS51869B (enExample)
SI (1) SI2146714T1 (enExample)
TW (1) TWI439269B (enExample)
UY (1) UY31035A1 (enExample)
WO (1) WO2008145841A1 (enExample)
ZA (1) ZA200907251B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104955808A (zh) * 2012-11-28 2015-09-30 赛诺菲 4-(环丙基甲氧基)-n-(3,5-二氯-1-氧化吡啶-4-基)-5-甲氧基吡啶-2-甲酰胺的晶型的制备方法以及晶型
US9624100B2 (en) 2014-06-12 2017-04-18 Apple Inc. Micro pick up array pivot mount with integrated strain sensing elements
WO2025080415A1 (en) * 2023-10-12 2025-04-17 Alto Neuroscience, Inc. Treatment of neuropsychiatric disorders with tilivapram
WO2025079694A1 (ja) * 2023-10-12 2025-04-17 株式会社 メドレックス 経皮吸収組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
ATE218549T1 (de) * 1993-07-28 2002-06-15 Aventis Pharma Ltd Verbindungen als pde iv und tnf inhibitoren
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
ATE290002T1 (de) * 1999-12-23 2005-03-15 Icos Corp Cyclische amp spezifische phosphodiesterase inhibitoren
EP1370211A4 (en) * 2001-03-02 2005-02-09 Bristol Myers Squibb Co SIMULTANEOUS ADMINISTRATION OF MELANOCORTIN RECEPTOR AGONISTS AND A PHOSPHODIESTERASE HEMMER FOR THE TREATMENT OF DISEASES RELATED TO CYCLIC AMP
AU2003281219A1 (en) * 2002-07-02 2004-01-23 Bernard Cote Di-aryl-substituted-ethane pyridone pde4 inhibitors
AU2004220456B2 (en) * 2003-03-12 2010-10-14 Celgene Corporation N-alkyl-hydroxamic acid-isoindolyl compounds and their pharmaceutical uses
WO2006135828A2 (en) * 2005-06-10 2006-12-21 Memory Pharmaceuticals Corporation Trisubstituted amines as phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
CA2684174C (fr) 2014-02-25
FR2915100A1 (fr) 2008-10-24
PT2146714E (pt) 2011-09-02
JO2678B1 (en) 2013-03-03
CA2684174A1 (fr) 2008-12-04
ZA200907251B (en) 2011-04-28
ATE513548T1 (de) 2011-07-15
EP2146714B1 (fr) 2011-06-22
CN101663035B (zh) 2012-06-20
US20100130554A1 (en) 2010-05-27
HK1141725A1 (en) 2010-11-19
HRP20110666T1 (hr) 2011-10-31
KR20150004885A (ko) 2015-01-13
KR20090130059A (ko) 2009-12-17
UY31035A1 (es) 2008-11-28
BRPI0810444A2 (pt) 2016-05-31
CN101663035A (zh) 2010-03-03
DK2146714T3 (da) 2011-10-10
SI2146714T1 (sl) 2011-10-28
ES2367408T3 (es) 2011-11-03
EA200970970A1 (ru) 2010-02-26
JP5386478B2 (ja) 2014-01-15
FR2915100B1 (fr) 2009-06-05
MY148092A (en) 2013-02-28
CY1111840T1 (el) 2015-10-07
TWI439269B (zh) 2014-06-01
AR066108A1 (es) 2009-07-22
AU2008257322A1 (en) 2008-12-04
KR101503942B1 (ko) 2015-03-18
TW200911247A (en) 2009-03-16
IL201448A (en) 2014-08-31
WO2008145841A1 (fr) 2008-12-04
MX2009011284A (es) 2009-11-02
RS51869B (sr) 2012-02-29
EA019194B1 (ru) 2014-01-30
ME00935B (me) 2012-06-20
PA8776801A1 (es) 2008-11-19
AU2008257322B2 (en) 2013-06-13
MA31367B1 (fr) 2010-05-03
PL2146714T3 (pl) 2011-10-31
IL201448A0 (en) 2010-05-31
EP2146714A1 (fr) 2010-01-27
NZ580482A (en) 2011-10-28
JP2010524906A (ja) 2010-07-22

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