PT2146714E - Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento dos distúrbios motores relacionados com a doença de parkinson - Google Patents

Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento dos distúrbios motores relacionados com a doença de parkinson Download PDF

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Publication number
PT2146714E
PT2146714E PT08787963T PT08787963T PT2146714E PT 2146714 E PT2146714 E PT 2146714E PT 08787963 T PT08787963 T PT 08787963T PT 08787963 T PT08787963 T PT 08787963T PT 2146714 E PT2146714 E PT 2146714E
Authority
PT
Portugal
Prior art keywords
oxidopyridin
cyclopropylmethoxy
carboxamide
parkinson
dichloro
Prior art date
Application number
PT08787963T
Other languages
English (en)
Portuguese (pt)
Inventor
Philippe Delay-Goyet
Claire Delgorge
Christine Menet
Gilles Poughon
Christine Ravinet-Trillou
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT2146714E publication Critical patent/PT2146714E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PT08787963T 2007-04-19 2008-04-16 Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento dos distúrbios motores relacionados com a doença de parkinson PT2146714E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702853A FR2915100B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxalide pour le traitement des desordres moteurs lies a la maladie de parkinson

Publications (1)

Publication Number Publication Date
PT2146714E true PT2146714E (pt) 2011-09-02

Family

ID=38712405

Family Applications (1)

Application Number Title Priority Date Filing Date
PT08787963T PT2146714E (pt) 2007-04-19 2008-04-16 Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento dos distúrbios motores relacionados com a doença de parkinson

Country Status (33)

Country Link
US (1) US20100130554A1 (enExample)
EP (1) EP2146714B1 (enExample)
JP (1) JP5386478B2 (enExample)
KR (2) KR20150004885A (enExample)
CN (1) CN101663035B (enExample)
AR (1) AR066108A1 (enExample)
AT (1) ATE513548T1 (enExample)
AU (1) AU2008257322B2 (enExample)
BR (1) BRPI0810444A2 (enExample)
CA (1) CA2684174C (enExample)
CL (1) CL2008001136A1 (enExample)
CY (1) CY1111840T1 (enExample)
DK (1) DK2146714T3 (enExample)
EA (1) EA019194B1 (enExample)
ES (1) ES2367408T3 (enExample)
FR (1) FR2915100B1 (enExample)
HR (1) HRP20110666T1 (enExample)
IL (1) IL201448A (enExample)
JO (1) JO2678B1 (enExample)
MA (1) MA31367B1 (enExample)
ME (1) ME00935B (enExample)
MX (1) MX2009011284A (enExample)
MY (1) MY148092A (enExample)
NZ (1) NZ580482A (enExample)
PA (1) PA8776801A1 (enExample)
PL (1) PL2146714T3 (enExample)
PT (1) PT2146714E (enExample)
RS (1) RS51869B (enExample)
SI (1) SI2146714T1 (enExample)
TW (1) TWI439269B (enExample)
UY (1) UY31035A1 (enExample)
WO (1) WO2008145841A1 (enExample)
ZA (1) ZA200907251B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9533953B2 (en) * 2012-11-28 2017-01-03 Sanofi Method of preparation of crystal forms of 4-(cyclopropylmethoxy)-n-(3,5-dichloro-1-oxidopyridyn-4-yl)-5-methoxypyridine-2-carboxamide and crystal forms thereof
US9624100B2 (en) 2014-06-12 2017-04-18 Apple Inc. Micro pick up array pivot mount with integrated strain sensing elements
WO2025080415A1 (en) * 2023-10-12 2025-04-17 Alto Neuroscience, Inc. Treatment of neuropsychiatric disorders with tilivapram
WO2025079694A1 (ja) * 2023-10-12 2025-04-17 株式会社 メドレックス 経皮吸収組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
ES2176251T3 (es) * 1993-07-28 2002-12-01 Aventis Pharma Ltd Compuestos utilizados como inhibidores de pde iv y del factor de necrosis tumoral(tnf).
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
CA2395196C (en) * 1999-12-23 2006-02-21 Icos Corporation Cyclic amp-specific phosphodiesterase inhibitors
EP1370211A4 (en) * 2001-03-02 2005-02-09 Bristol Myers Squibb Co SIMULTANEOUS ADMINISTRATION OF MELANOCORTIN RECEPTOR AGONISTS AND A PHOSPHODIESTERASE HEMMER FOR THE TREATMENT OF DISEASES RELATED TO CYCLIC AMP
WO2004005258A1 (en) * 2002-07-02 2004-01-15 Merck Frosst Canada & Co. Di-aryl-substituted-ethane pyridone pde4 inhibitors
CA2518513C (en) * 2003-03-12 2014-05-20 Celgene Corporation N-alkyl-hydroxamic acid-isoindolyl compounds and their pharmaceutical uses
WO2006135828A2 (en) * 2005-06-10 2006-12-21 Memory Pharmaceuticals Corporation Trisubstituted amines as phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
KR20090130059A (ko) 2009-12-17
NZ580482A (en) 2011-10-28
KR101503942B1 (ko) 2015-03-18
AU2008257322B2 (en) 2013-06-13
JP2010524906A (ja) 2010-07-22
BRPI0810444A2 (pt) 2016-05-31
DK2146714T3 (da) 2011-10-10
MY148092A (en) 2013-02-28
CN101663035A (zh) 2010-03-03
EP2146714B1 (fr) 2011-06-22
AR066108A1 (es) 2009-07-22
FR2915100B1 (fr) 2009-06-05
EP2146714A1 (fr) 2010-01-27
SI2146714T1 (sl) 2011-10-28
PL2146714T3 (pl) 2011-10-31
TWI439269B (zh) 2014-06-01
JP5386478B2 (ja) 2014-01-15
IL201448A0 (en) 2010-05-31
WO2008145841A1 (fr) 2008-12-04
FR2915100A1 (fr) 2008-10-24
US20100130554A1 (en) 2010-05-27
RS51869B (sr) 2012-02-29
EA019194B1 (ru) 2014-01-30
UY31035A1 (es) 2008-11-28
HRP20110666T1 (hr) 2011-10-31
PA8776801A1 (es) 2008-11-19
AU2008257322A1 (en) 2008-12-04
ES2367408T3 (es) 2011-11-03
JO2678B1 (en) 2013-03-03
CN101663035B (zh) 2012-06-20
CA2684174A1 (fr) 2008-12-04
CY1111840T1 (el) 2015-10-07
MX2009011284A (es) 2009-11-02
CA2684174C (fr) 2014-02-25
ZA200907251B (en) 2011-04-28
TW200911247A (en) 2009-03-16
HK1141725A1 (en) 2010-11-19
ME00935B (me) 2012-06-20
CL2008001136A1 (es) 2009-01-16
MA31367B1 (fr) 2010-05-03
KR20150004885A (ko) 2015-01-13
EA200970970A1 (ru) 2010-02-26
ATE513548T1 (de) 2011-07-15
IL201448A (en) 2014-08-31

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