CH709832B1 - Transfer device. - Google Patents

Abstract

The invention relates to a transfer device (10) for transferring a fluid from a first container (40) into a second container (50), comprising a connecting element (11) with a transfer channel (13) which can be opened by a shut - off element (20) is to be closed, and further comprising two connection adapters (30, 31) each having a hollow needle (32), wherein in each case a continuous hollow needle channel in the two hollow needles (32) and the transfer channel (13) in the longitudinal axis direction (12) of the transfer device (10) are interconnected throughout. The shut-off element (20) is equipped with an unlocking device (25) and installed in the initial position in the locked closed position (100) in the connecting element (11).

Description

Description: The invention relates to a transfer device for transferring a fluid from a first container into a second container with the features of the preamble of claim 1.

Such a transfer device is used to transfer a fluid from a first container into a second container, the two containers are each closed with a stopper or a membrane. By means of hollow needles, so-called spikes, which are attached to the free ends of the transfer device and whose internal transfer channels are connected to one another, the plugs or membranes of the two containers can be pierced, whereby the transfer channels form a connection between the two containers and that in the two Containers can be mixed with each other separately stored products.

Such transfer devices are mainly used in the medical field for transferring and removing liquids, in particular from containers, and for mixing liquids with solid substances. Such devices are aimed in particular at transferring a liquid from a first container into a second container filled with a powdery substance for the purpose of dissolving this powdery substance. In order to increase the shelf life of active ingredients in medicine, media are, for example, freeze-dried in solid form and mixed with a liquid medium before use. For this purpose, the freeze-dried medium is stored in a first container and a liquid solvent in another container. So-called double spikes are usually used to mix the two media, each of which has a needle at its two opposite ends with a continuous internal transfer channel in order to be able to pierce the openings of the two containers, which are usually sealed with a stopper. To support the mass transport within the transfer channel of the double spike, one of the two containers is usually acted on with a vacuum. Usually, a vacuum is created in the container with the dry, solid substance, so that when the double spike is pierced, the liquid from the other container is sucked into the vacuumed container with the solid present.

A disadvantage of these double spikes is that the two needles protrude unprotected at the opposite free ends of the double spikes, which is why the risk of injury when handling such double spikes is particularly high. Another disadvantage is that when using a double spike with a continuous transfer channel, a special sequence in the sequence of piercing the double spike on the two containers must be observed. If, by mistake, the container under pressure is first pierced with the solid present, the vacuum has already escaped from this container before the second container with the liquid solvent has been infected. A transfer of the solvent through the double spike into the solid of the other container is therefore usually no longer possible due to the high frictional resistance or the capillary effect within the transfer channel, which is why the pierced container and the double spike used must be discarded and each unopened container with a fresh one Double spike must now be pierced again in the reverse order and connected. Due to the increased expenditure of time and the unused containers to be disposed of, which were accidentally punctured in the wrong order, this solution is neither economical nor sustainable.

Different embodiments of lockable transfer devices are known from the prior art. In the case of lockable transfer devices, it is possible to shut off the transfer channel inside the transfer device before piercing the two containers filled with different products, and thus to prevent a suppression in one of the two containers from being reduced first, if the order of piercing of the two containers is reversed the second container is attached to the transfer device.

For example, document DE 4 122 221 A1 discloses a device with a transfer and removal spike, which is equipped with a displaceable shut-off element. A disadvantage of this device is that the two piercing domes each protrude unprotected from the housing of the device, which is why there is also an increased risk of injury when handling the device. A further disadvantage here is that the shut-off element which can be moved in the transverse direction to the transfer channel is equipped with two parallel transfer or ventilation channels and is therefore complex to manufacture.

Furthermore, a transfer device with a shut-off piston is known from document US 2011/0 087 164 A1, in which the two hollow needles or spikes are each surrounded by bell-shaped connecting parts at least along one longitudinal section and are therefore not unprotected in their entire spike length by the Remove transfer device. In this embodiment, the risk of injury when handling the spikes is at least reduced. However, it is also disadvantageous that the two bell-shaped connecting parts for connecting the containers are connected in one piece to the shut-off piston. A flexible use of the transfer device for connecting different types of containers or differently shaped container openings is therefore not possible. Another disadvantage is that the position of the shut-off piston can be rotated before the transfer device has been attached to correspondingly corresponding containers, which is why a mix-up-safe use of the transfer device without incorrect operation is not guaranteed here either.

CH 709 832 B1 It is therefore the object of the present invention to provide a lockable transfer device which avoids the disadvantages of the prior art described.

This object is achieved in a transfer device according to the preamble of claim 1 with the features of the characterizing part of claim 1. The dependent claims relate to further particularly advantageous embodiments of the invention.

In an inventive transfer device for transferring a fluid from a first container into a second container, comprising a connecting element with a transfer channel, which can be opened and closed by a shut-off element, and further comprising two connecting adapters, each with a hollow needle, each of which a continuous hollow needle channel in the two hollow needles and the transfer channel in the longitudinal axis direction of the transfer device are continuously connected to one another, the shut-off element is equipped with an unlocking device and installed in the locked position in the connecting element in the starting position. In this embodiment of a lockable transfer device according to the invention, it is thus ensured that at the time of delivery, the transfer channel is closed by the locked shut-off element and therefore no particular sequence when piercing the two closed containers has to be observed. The use of transfer devices according to the invention advantageously increases the sustainability and economy in the handling of medical products, since containers accidentally pierced in the wrong order no longer have to be discarded and disposed of unused.

In a transfer device according to the invention, the two connection adapters are particularly advantageously each exchangeably attached to the connection element. In this preferred embodiment of the invention, different connection adapters can be attached to the transfer device. Thus, connecting elements of a single type with different connecting adapters, which are each adapted to the opening sizes of the respective containers, can be used together. This simplification of warehouse logistics saves costs, particularly in the healthcare sector. Furthermore, the production costs of transfer devices are reduced since, if necessary, only different types of connection adapters have to be produced and kept in stock, but the connecting element in between can always be used in the same type. The use of hollow needles, which are arranged in a protected manner within the essentially bell-shaped side plates of the connection adapter, further minimizes the risk of injury when handling the connection adapter or the transfer devices.

[0012] In a transfer device according to the invention, the two connection adapters are expediently each screwed to a connecting thread section of the connection element. In this embodiment, the connection adapters are screwed onto the connection element or, if necessary, they can also be unscrewed from the connection element and replaced. A liquid-tight connection of the connecting adapter and connecting element is achieved by the threaded sections.

In a further development of the invention, in a transfer device, the connecting thread sections of the connecting element each have an internal thread, which is complementary to an external connecting thread on a connecting sleeve of the connecting adapter. In this embodiment, the internal thread sections on the connecting element are particularly advantageously protected against damage to the thread during storage.

In the context of the invention, however, it is also conceivable to use a transfer device in which the connecting thread sections of the connecting element are each designed as external threads, which is complementary to an internal connecting thread on a connecting sleeve of the connecting adapter.

[0015] In a transfer device according to the invention, connection adapters in different versions are expediently attachable to the connection element. In this embodiment, the flexibility when using transfer devices according to the invention is advantageously increased. Different connection adapters or different container sizes and shapes can thus be connected to a transfer device according to the invention.

Particularly expediently, in a transfer device according to the invention, each connection adapter each has a connecting sleeve which tapers conically to the hollow needle, optionally for connection to a conical sealing surface of a connecting piece of the connection element or for connection to a syringe. In this embodiment, connection adapters can be connected particularly flexibly to the connection element of a transfer device according to the invention or to a conical nozzle opening of a disposable or reusable syringe. For example, a container that has already been opened by piercing with a hollow needle of a connecting element of the transfer device and partially emptied by means of the transfer device can be completely emptied with this syringe by pulling the connecting element off the connecting adapter and then plugging in a syringe nozzle. Or, for example, a further volume of solvent can be pressed through the hollow needle channel into the attached container using a syringe. The connection sleeve of the connecting adapter, which tapers conically in the longitudinal axis direction towards the hollow needle, achieves both a sealing effect against the complementarily shaped conical sealing surface of the connecting piece of the connecting element and, if necessary, a sealing effect against a conically tapering syringe opening. Due to the possibility with attached connection adapters

CH 709 832 B1 already open containers can be connected either with the transfer device as well as with common disposable or reusable syringes, the flexibility and user-friendliness of the transfer device according to the invention is advantageously further increased.

This also overcomes the disadvantage known from the prior art of oppositely shaped «male» or «female» connection pairs, in which - if at all - only on one of the two complementary connection parts, usually only on the «female» , Connecting part of a syringe or a comparable medical injection device can be plugged on.

In a particularly safe embodiment of the invention, a free hollow needle length of the hollow needle measured in a transfer device in the longitudinal axis direction is shorter than a depth of at least one side flap of the connecting adapter surrounding the hollow needle. In this preferred embodiment, the bell-shaped outer parts or side straps of the connecting adapter protrude from the central hollow needle located within the side straps, which is why particularly safe and injury-free handling of the transfer device is ensured in this embodiment.

In a transfer device according to the invention, one-piece connection adapters expediently comprising a hollow needle and at least one side flap surrounding the hollow needle can expediently be used.

In a particularly advantageous embodiment of the invention, in a transfer device the shut-off element comprises a shut-off valve which is rotatably mounted in a shut-off sleeve essentially transversely to the longitudinal axis direction of the connecting element. A shut-off element comprising a shut-off valve, which is installed transversely to the transfer channel in the connecting element, offers numerous advantages. Stopcocks are particularly well established and accepted in the medical field. Appropriate design of the shut-off sleeve and the shut-off valve rotatably mounted therein ensure that it is particularly easy to operate with a liquid-tight seal. For example, the shut-off valve can be designed with a conically tapering sealing surface and its position within the shut-off sleeve can additionally be rotatably secured in position within the shut-off sleeve with sealing rings and / or a sealing thread.

Appropriately, in a transfer device according to the invention, the shut-off valve has a channel bore which is arranged coaxially with the transfer channel in an open flow position of the shut-off element.

In a transfer device according to the invention, a channel bore of the shut-off valve advantageously has the same channel cross section as the transfer channel. In this embodiment, the flow resistance in the channel is advantageously reduced by the same channel cross section of the transfer channel and the channel bore inside the shut-off valve.

In a further preferred embodiment of the invention, in a transfer device, the shut-off element comprises a shut-off slide which is mounted so that it can be pushed in and pulled out substantially transversely to the longitudinal axis direction. In this embodiment, the shut-off element is formed by a slidable slide valve instead of a shut-off valve. Depending on the version, the gate valve can be actuated, for example, by pressing it into a shut-off sleeve or by pulling it out of a shut-off sleeve of the connecting element. It is also conceivable within the scope of the invention to provide a gate valve which can be brought into an open flow position by pushing in as well as by pulling it out of a position closed upon delivery. For this purpose, the gate valve also has an unlocking lock, which ensures that the gate valve is in a locked, closed position when the transfer device is delivered.

In a transfer device according to the invention, the unlocking device is particularly advantageously arranged on an actuating handle of the shut-off element. Within the scope of the invention, different design variants of an unlocking lock known per se from the prior art can be used. For example, tabs or burrs, which are arranged on the outside of the shut-off sleeve and extend into recesses on the underside of the actuating handle, can serve as an unlocking device and act on the shut-off element, for example on the shut-off valve or gate valve. The actuating handle of a shut-off valve is formed, for example, by two tabs projecting laterally opposite one another, which are comparable to the wings of a wing nut. The actuating handle of a gate valve is formed, for example in the case of a push-in gate valve, by an actuating surface on which a person can press the gate valve in the transverse direction by pressing with a finger. If a gate valve is used that can be opened by pulling it out in the transverse direction, the actuating handle can be formed, for example, by a grip tab on which the gate valve can be pulled from its locked position to its open position. Due to the advantageous arrangement of the unlocking device on the actuating handle of the shut-off element, when the shut-off element is actuated for the first time to open the transfer channel, the unlocking can be heard and / or felt, for example, which further improves the operational safety when handling the inventive transfer device.

In a preferred embodiment of the invention, in a transfer device, the shut-off valve can be moved from its initial position in the locked, closed position into an unlocked, closed position by moving a normal distance in the transverse axis direction. In this version, the shut-off valve is first unlocked by moving it in the transverse axis direction, although the transfer channel remains closed for the time being.

CH 709 832 B1 [0026] In a preferred embodiment of the transfer device, the normal distance in the transverse axis direction is a maximum of 2 mm, preferably a maximum of 1 mm. It is thus also possible for the user to determine whether the shut-off valve is still in the locked or already unlocked closed position. The normal distance in the transverse axis direction is measured between a lower edge of the movable stopcock and a lower edge of the surrounding shut-off sleeve.

In a transfer device according to the invention, the shut-off valve can expediently be brought from its unlocked closed position into an open flow position by turning about the transverse axis. In this embodiment, for example, the shut-off valve is first unlocked by moving it in the transverse axis direction, the shut-off valve still remaining in a closed position. In a further step, the shut-off valve is brought from the closed position into a flow-through position with a continuous transfer channel by rotating it about the transverse axis.

In an advantageous development of the invention, in a transfer device, the shut-off element has a conical sealing surface and / or at least one sealing ring and / or a sealing thread, which acts or act in a sealing manner with respect to the surrounding shut-off sleeve. Depending on the safety requirement when operating the transfer device, shut-off elements can be used which have a plurality of sealing devices which are independent of one another, in order to ensure that media can escape from the transfer device during the transfer from one container into the other container, both in the locked and in the open position. This is particularly advantageous if particularly valuable or particularly health-critical substances are to be mixed with one another.

Further details, features and advantages of the invention result from the following explanation of exemplary embodiments schematically illustrated in the drawings. In the drawings:

Figure 1 is an oblique isometric view from the front of a first embodiment of a transfer device according to the invention with two identical connection adapters for fastening a first and a second container.

FIG. 2, corresponding to the device shown in FIG. 1, a variant with two different connection adapters for fastening a first and a second container;

3 is an exploded isometric view of a transfer device according to the invention with a first connection adapter for attaching a first container to its upper free end and optionally two different variants of connection adapters for attaching a second container to its lower free end;

Figure 4 is a front view of a transfer device according to the invention with attached containers in the locked closed position.

5 according to the sectional plane A-A shown in FIG. 4, the transfer device in a sectional view from the front;

6 shows an enlarged detail view of the detail X marked in FIG. 5;

7 is a front view of a transfer device according to the invention with the containers plugged in in the unlocked closed position;

8 according to the sectional plane B-B shown in FIG. 7, the transfer device in a sectional view from the front;

9 is an enlarged detail view of the detail Y marked in FIG. 8;

Fig. 10 is a front view of a transfer device according to the invention with attached containers in the open

Flow position;

11 according to the sectional plane C-C shown in FIG. 10, the transfer device in a sectional view from the front;

12 shows an enlarged detail view of the detail Z marked in FIG. 11.

Fig. 1 shows an isometric oblique view of a first embodiment of a transfer device 10 according to the invention with a shut-off element 20 and with two similar connection adapters 30 for fastening a first container 40 and a second container 50 to the transfer device 10. The transfer device 10 further comprises a Elongated connecting element 11 with a longitudinal axis 12, which connecting element 11 has a transfer channel 13 which is arranged in the longitudinal axis direction 12 inside the connecting element 11. A shut-off sleeve 14, which in the connecting element 11 in a transverse axis direction 15 essentially transverse to the longitudinal axis direction 5

CH 709 832 B1 device 12 is arranged, serves to receive the closable or openable shut-off element 20. Furthermore, sections of a connecting thread 16 are arranged on the two free ends of the connecting element 11 located in the longitudinal axis direction 12. The connection thread 16 is designed here as an internal thread 16. A connecting piece 17 with a conical sealing surface 18 serves as a connection holder for attaching the connection adapter 30. The connecting piece 17 has a smaller outside diameter than the outside diameter of the cylindrical main part of the connecting element 11. The sealing surface 18 tapers conically to the free end of the connecting piece 17 ,

The shut-off element 20 here comprises a shut-off valve 21 which is equipped with an actuating handle 22 at its upper free end. The shut-off valve 21 has a sealing surface 23 which tapers conically downward in the transverse axis direction 15 or away from the actuating handle 22 into the interior of the connecting element 11 and which acts as a seal against the complementarily shaped shut-off sleeve 14. A channel bore 24 is arranged essentially perpendicular to the transverse axis direction 15 of the shut-off valve 21 in such a way that the channel bore 24 can be connected coaxially or collinearly to the continuous transfer channel 13 in the open flow position.

An unlocking device 25 is provided on the operating handle 22. The unlocking lock 25 ensures that the shut-off element 20, or here the shut-off valve 21, is in a locked, closed position 100 with a locked transfer channel 13 when the transfer device 10 is delivered.

Inside each connection adapter 30 is secured in a protected position by the surrounding side walls of the bell-shaped connection adapter 30 each have a hollow needle 32 or a so-called spike with an inner hollow needle channel 33 and a hollow needle length 34. The side walls of the connection adapter 30 shown here are each formed from two sectionally interrupted side plates 38, which serve as protection against injury when handling the hollow needles 32. Bracket catches 39 are provided on the inside of each of the side straps 38. The hollow needle 32 arranged centrally within the side flaps 38 serves to pierce a sealing plug 41 as a closure of the first container 40 and a sealing plug 51 as a closure of the second container 50 and thus to establish a connection to the respective container contents by means of the hollow needle channel 33. The mounting catches 39 on the side straps 38 are designed such that, like a snap closure, they overlap protrusions on a container neck 42 of the first container 40 or on a container neck 52 of the second container 50 and snap or snap into these projections. For example, flanged edges of sealing caps or the outer edges of the sealing plugs 41 and 51 serve as projections on the container neck 42 and 52. The mounting catches 39 ensure a secure fit of the connected connection adapters 30, 31 on the respective container neck 42 and 52. In order to be able to remove the connection adapters 30, 31 again from the containers 40, 50, if necessary, the resiliently movable side flaps 38 are spread apart by hand until their inner mounting catches 39 no longer snap into the projections on the respective container neck 42, 52 and are pulled off can. Depending on the design, a plurality of mounting catches 39 can also be arranged on the side flaps 38, each to be snapped onto differently shaped container necks.

Fig. 2 illustrates, corresponding to the transfer device 10 shown in Fig. 1, a variant with two different connection adapters 30, 31 for fastening a first container 40 and a second container 50. The connection adapters 30 and 31 are each made in one piece here.

Fig. 3 shows an isometric exploded view of a transfer device 10 according to the invention with a first connection adapter 30 for attaching a first container, not shown here, to its upper free end and optionally two different variants of connection adapters 30 and 31 for attaching a second , also not shown container at its lower free end. A shut-off valve 21 is shown here as a shut-off element 20 with an actuating handle 22 at its upper free end and a sealing surface 23 that tapers conically downward. At the lower free end of the sealing surface 23, a sealing ring 27 and a sealing thread 28 are additionally provided here.

The connection adapter 30 has a larger connection cross section for connecting a container with a larger container opening. Other adapters, for example a connection adapter 31 with a smaller connection cross section, for connecting a container with a smaller container opening can also optionally be attached to the connection element. For this purpose, a conical connection sleeve 35 with a connection thread 36 is provided on each connection adapter 30, 31. The connection thread 36 is designed here as an external thread 36 complementary to the internal thread 16 on the connecting element 11. The connection adapters 30 and 31 each have side tabs 38 with a depth 37 in the longitudinal axis direction 12 which, for safety reasons, is greater than the length 34 of the hollow needle 32. The each in the longitudinal axis direction 12 is conically inward, that is to say in the direction of the respective hollow needle 32 , Tapered connection sleeves 35 are used to attach to the conical sealing surface 18 of the connection piece 17 of the connecting element 11, as shown here in FIG. 3. Likewise, one-way or reusable syringes or comparable other medical injection instruments, which are each equipped with a conical nozzle opening, can be attached to the conical connection sleeves 35. Infected syringes are not explicitly shown in the figures for the sake of clarity.

CH 709 832 B1 FIG. 4 shows a front view of a transfer device 10 according to the invention in the locked closed position 100 with containers 40, 50 already plugged in. The transfer device 10 according to the invention is delivered in this locked position 100 of the shut-off element 20 without a plugged container. When the two containers 40, 50 are plugged into the connecting adapters 30, it is advantageous not to observe a specific sequence.

5 relates to the transfer device 10 in a sectional view according to the sectional plane A-A shown in FIG. 4.

6 shows an enlarged detail view of the detail X of the transfer device 10 marked in FIG. 5. In particular in FIG. 6 it can be clearly seen that the unlocking device 25 is arranged here on the actuating handle 22 of the shut-off valve 21. In the locked position 100, the shut-off valve 21 is flush with its lower edge and without a normal distance 26 in the transverse axis direction 15 with a lower edge of the surrounding shut-off sleeve 14. 6, the depth 37 of the side flaps 38 of the connection adapter 30 can be seen in section on the left in the image, which for safety reasons is greater than the length 34 of the hollow needle 32 arranged centrally in the longitudinal axis direction 12 of the connection adapter 30.

FIG. 7 shows a front view of a transfer device 10 according to the invention with containers 40, 50 already plugged in in the unlocked closed position 200.

FIG. 8 shows the transfer device 10 in a sectional view according to the sectional plane B-B shown in FIG. 7.

FIG. 9 illustrates in an enlarged detail view the detail Y marked in FIG. 8. By moving in the direction of displacement 210 or in the transverse axis direction 15 upward, the shut-off valve 21 is brought from the locked closing position 100 into an unlocked closing position 200. Depending on the design of the unlocking device 25, for example, a resistance must be overcome or a connecting tab, which connects the actuating handle 22 to the outside of the shut-off sleeve 14 as a means of preventing rotation, must be sheared off. In the unlocked closed position 200, the transfer channel 13 is still closed. In the unlocked closed position 200, the lower edge of the shut-off valve 21 is spaced at a normal distance 26 in the transverse axis direction 15 from the lower edge of the surrounding shut-off sleeve 14. The normal distance 26 between the lower edge of the shut-off valve 21 and the lower edge of the shut-off sleeve 14 is, for example, 1 mm.

10 shows a front view of a transfer device 10 according to the invention with containers 40, 50 already attached, in the open flow position 300. Starting from the unlocked closed position 200 of the shut-off element 20 shown in FIGS. 7 to 9, this is achieved by turning in the direction of rotation 310, that is, by rotating about the transverse axis 15, moved into an open flow position 300. In this position, the two hollow needle channels 33 and the transfer channel 13 are continuously connected to one another, and the media stored separately in the two containers 40 and 50 can now be contacted or mixed with one another.

FIG. 11 shows the transfer device 10 in a sectional view according to the sectional plane C-C shown in FIG. 10.

12 shows an enlarged detail view of the detail Z marked in FIG. 11.

For the sake of clarity, the parts of the transfer device 1 shown in FIGS. 1 to 12 are each shown as transparent components. With the exception of a sealing ring 27, which is made, for example, of an elastomer, all other components can be made of a transparent plastic, for example.

The invention is not limited to the embodiment variants explicitly shown in the figures. Within the scope of the invention, it is also possible to provide as a shut-off element 20 instead of a shut-off valve 21 a shut-off slide on the connecting element 11, which is mounted so as to be displaceable essentially transversely to the longitudinal axis direction 12. For this purpose, the gate valve can be unlocked or opened by pushing in and / or pulling out a movable slide part on the connecting element. According to the invention, the gate valve is also provided with an unlocking device which ensures that the gate valve is installed in the locking element in the locked closing position upon delivery.

It is also possible, for example, to carry out different variants of unlocking locks in the context of the invention or to use unlocking locks which do not act directly on the actuating handle.

List of position symbols:

[0049]

transfer device

connecting element

Longitudinal axis of the connecting element

CH 709 832 B1

transfer channel

Shut-off sleeve for shut-off element

Transverse axis of the shut-off sleeve

Connection thread (inside)

Connection piece conical sealing surface of the connection piece

shut-off

stopcock

Shut-off valve operating handle

Stopcock sealing surface

channel bore

unlocking

Normal distance in the transverse axis direction

sealing ring

seal thread

Connection adapter, first variant

Connection adapter, second variant

cannula

Hollow needle channel

Hollow needle length conical connection sleeve

Connection thread (outside)

Connection adapter depth

Side tabs of the connection adapter Bracket catch first container

sealing plug

Container neck second container

sealing plug

Container neck locked locking position unlocked locking position

Direction of shut-off valve (arrow direction) open flow position

Direction of rotation of the shut-off valve (direction of arrow)

CH 709 832 B1

Claims (15)

claims 1. Transfer device (10) for transferring a fluid from a first container (40) into a second container (50), comprising a connecting element (11) with a transfer channel (13) which can be opened and closed by a shut-off element (20) and further comprising two connection adapters (30, 31), each with a hollow needle (32), a continuous hollow needle channel (33) in each of the two hollow needles (32) and the transfer channel (13) in the longitudinal axis direction (12) of the transfer device (10 ) are continuously connected to each other, characterized in that the shut-off element (20) is equipped with an unlocking device (25) and is installed in the connecting element (11) in the locked position (100) in the starting position. 2. Transfer device (10) according to claim 1, characterized in that the two connection adapters (30, 31) are each exchangeably attached to the connecting element (11). 3. Transfer device (10) according to spoke 2, characterized in that the two connecting adapters (30, 31) are each screw-fastened to a connecting thread section (16) of the connecting element (11). 4. Transfer device according to claim 3, characterized in that the connecting thread sections (16) of the connecting element (11) each have an internal thread which is complementary to an external connecting thread (36) on a connecting sleeve (35) of the connecting adapter (30, 31). 5. Transfer device (10) according to any one of claims 2 to 4, characterized in that each connection adapter (30, 31) each have a conical tapering to the hollow needle (32) connecting sleeve (35) optionally for plugging into a conical sealing surface (18) Has connecting piece (17) of the connecting element (11) or for connecting to a syringe. 6. Transfer device (10) according to one of the preceding claims, characterized in that in each case measured in the longitudinal axis direction (12) a free hollow needle length (34) of the hollow needle (32) is shorter than a depth (37), at least one of the hollow needle (32) surrounding side flap (38) of the connecting adapter (30, 31). 7. Transfer device (10) according to claim 6, characterized in that the connection adapter (30, 31) comprising the hollow needle (32) and at least one said side flap (38) is made in one piece. 8. Transfer device (10) according to any one of the preceding claims, characterized in that the shut-off element (20) comprises a shut-off valve (21) which in a shut-off sleeve (14) essentially transversely (15) to the longitudinal axis direction (12) of the connecting element (11 ) is rotatably mounted. 9. Transfer device (10) according to claim 8, characterized in that the shut-off valve (21) has a channel bore (24) which is arranged in an open flow position (300) of the shut-off element (20) coaxially with the transfer channel (13). 10. Transfer device (10) according to claim 8 or 9, characterized in that a channel bore (24) of the shut-off valve (21) has the same channel cross-section as the transfer channel (13). 11. Transfer device (10) according to one of claims 1 to 7, characterized in that the shut-off element (20) comprises a gate valve, which is mounted transversely (15) to the longitudinal axis direction (12) and can be pushed in and pulled out movably. 12. Transfer device (10) according to one of the preceding claims, characterized in that the unlocking device (25) is arranged on an actuating handle (22) of the shut-off element (20). 13. Transfer device (10) according to one of claims 8 to 10, characterized in that the shut-off valve (21) by moving (210) a normal distance (26) in the transverse axis direction (15) from its initial position in the locked closed position (100) in one unlocked closing position (200) can be brought. 14. Transfer device (10) according to claim 13, characterized in that the normal distance (26) is a maximum of 2 mm, preferably a maximum of 1 mm. 15. Transfer device (10) according to claim 13 or 14, characterized in that the shut-off valve (21) by turning (310) about the transverse axis (15) from its unlocked closed position (200) can be brought into an open flow position (300). CH 709 832 B1 -5Ä CH 709 832 B1 Λ5 ³ 3 3 £ CH 709 832 B1 ^3o / ο ΛΛ ^3c ^ // xsy / / y / Av ___ p yy · 'B ...................'............: j -4cJ ^1: -5o , W3 1 -