CH674315A5 - - Google Patents
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- Publication number
- CH674315A5 CH674315A5 CH455187A CH455187A CH674315A5 CH 674315 A5 CH674315 A5 CH 674315A5 CH 455187 A CH455187 A CH 455187A CH 455187 A CH455187 A CH 455187A CH 674315 A5 CH674315 A5 CH 674315A5
- Authority
- CH
- Switzerland
- Prior art keywords
- column
- segment
- hollow
- base segment
- stationary phase
- Prior art date
Links
- 239000000126 substance Substances 0.000 claims description 17
- 230000005526 G1 to G0 transition Effects 0.000 claims description 16
- 239000002904 solvent Substances 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 13
- 238000004587 chromatography analysis Methods 0.000 claims description 12
- 238000000926 separation method Methods 0.000 claims description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 11
- 239000011521 glass Substances 0.000 claims description 9
- 239000000945 filler Substances 0.000 claims description 7
- 239000000470 constituent Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 5
- 238000013375 chromatographic separation Methods 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 4
- 238000012360 testing method Methods 0.000 claims description 4
- 238000002474 experimental method Methods 0.000 claims description 3
- 239000011877 solvent mixture Substances 0.000 claims description 3
- 229910000831 Steel Inorganic materials 0.000 claims description 2
- 239000011261 inert gas Substances 0.000 claims description 2
- 239000010959 steel Substances 0.000 claims description 2
- 230000001174 ascending effect Effects 0.000 claims 1
- 239000005388 borosilicate glass Substances 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- -1 polytetrafluoroethylene Polymers 0.000 claims 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 1
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 1
- 239000010409 thin film Substances 0.000 claims 1
- 239000012780 transparent material Substances 0.000 claims 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 18
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
- 239000000741 silica gel Substances 0.000 description 8
- 229910002027 silica gel Inorganic materials 0.000 description 8
- 239000000523 sample Substances 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 229920006395 saturated elastomer Polymers 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 238000003820 Medium-pressure liquid chromatography Methods 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000004880 explosion Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- HEZMWWAKWCSUCB-PHDIDXHHSA-N (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylic acid Chemical compound O[C@@H]1C=CC(C(O)=O)=C[C@H]1O HEZMWWAKWCSUCB-PHDIDXHHSA-N 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000001840 cholesterol esters Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- DEZRYPDIMOWBDS-UHFFFAOYSA-N dcm dichloromethane Chemical compound ClCCl.ClCCl DEZRYPDIMOWBDS-UHFFFAOYSA-N 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 1
- 239000000550 preparative sample Substances 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000009419 refurbishment Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002594 sorbent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010414 supernatant solution Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6069—Construction of the column body with compartments or bed substructure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8411—Intermediate storage of effluent, including condensation on surface
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8881—Modular construction, specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6047—Construction of the column with supporting means; Holders
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH455187A CH674315A5 (enrdf_load_stackoverflow) | 1987-11-23 | 1987-11-23 | |
| DE19883836343 DE3836343A1 (de) | 1987-11-23 | 1988-10-25 | Saeulenchromatograph und verfahren zu dessen betrieb |
| NL8802797A NL8802797A (nl) | 1987-11-23 | 1988-11-14 | Kolomchromatograaf en werkwijze voor het bedrijven daarvan. |
| GB8827069A GB2212738A (en) | 1987-11-23 | 1988-11-18 | Column for chromatography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH455187A CH674315A5 (enrdf_load_stackoverflow) | 1987-11-23 | 1987-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH674315A5 true CH674315A5 (enrdf_load_stackoverflow) | 1990-05-31 |
Family
ID=4278186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH455187A CH674315A5 (enrdf_load_stackoverflow) | 1987-11-23 | 1987-11-23 |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH674315A5 (enrdf_load_stackoverflow) |
| DE (1) | DE3836343A1 (enrdf_load_stackoverflow) |
| GB (1) | GB2212738A (enrdf_load_stackoverflow) |
| NL (1) | NL8802797A (enrdf_load_stackoverflow) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2119159C1 (ru) * | 1997-02-17 | 1998-09-20 | Владимир Дмитриевич Ефимов | Устройство для хроматографического разделения смеси газов и паров |
| WO2002053256A1 (en) * | 2001-01-05 | 2002-07-11 | Pro-Chem, Inc. | Devices and methods for purification |
| DE102004041806B4 (de) * | 2004-08-25 | 2014-10-16 | Analyticon Discovery Gmbh | Verfahren und Vorrichtung zur Auftrennung von Stoffgemischen |
| CA2584372A1 (en) * | 2004-11-04 | 2006-05-11 | Bio-Rad Pasteur | Stackable chromatography module and chromatography column comprising a stack of such modules |
| DE102005024154B3 (de) * | 2005-05-23 | 2007-02-08 | Bischoff Analysentechnik und -geräte GmbH | Elemente zur Trennung von Substanzen durch Verteilung zwischen einer stationären und einer mobilen Phase und Verfahren zur Herstellung einer Trennvorrichtung |
| RU2349912C1 (ru) * | 2007-07-05 | 2009-03-20 | Владимир Дмитриевич Ефимов | Устройство для хроматографического разделения смеси газов и паров |
| GB0801127D0 (en) * | 2008-01-22 | 2008-02-27 | Ge Healthcare Bio Sciences Ab | Method for removing air from a chromatography column |
| CN101954202B (zh) * | 2009-07-16 | 2012-07-25 | 中国科学院化学研究所 | 恒压密闭上行层析柱装置及装置的应用方法 |
| US9689848B2 (en) * | 2013-09-30 | 2017-06-27 | Sekisui Medical Co., Ltd. | Column contained in container and column container |
| CN103752039B (zh) * | 2014-01-07 | 2015-09-30 | 南京诺云生物科技有限公司 | 自支撑模组化色谱柱及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2008354A1 (de) * | 1970-02-23 | 1971-09-09 | Boehnnger Mannheim GmbH, 6800 Mann heim | Kombinationssaule |
| GB1149852A (en) * | 1965-01-22 | 1969-04-23 | Alfred George Wright | Improvements relating to apparatus for performing scientific experiments |
| SE8205033L (sv) * | 1982-09-03 | 1984-03-04 | Nils M L Engstrom | Delbar kromatografipelare med detekterings- och signalanordning samt elueringsystem - i kombination eller fristaende |
| FR2575666B1 (fr) * | 1985-01-04 | 1989-08-18 | Centre Nat Rech Scient | Procede et dispositif pour la separation chromatographique de macromolecules biologiques |
| US4719011A (en) * | 1985-03-22 | 1988-01-12 | H. T. Chemicals, Inc. | High pressure liquid chromatography columns |
-
1987
- 1987-11-23 CH CH455187A patent/CH674315A5/de not_active IP Right Cessation
-
1988
- 1988-10-25 DE DE19883836343 patent/DE3836343A1/de not_active Withdrawn
- 1988-11-14 NL NL8802797A patent/NL8802797A/nl not_active Application Discontinuation
- 1988-11-18 GB GB8827069A patent/GB2212738A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| GB2212738A (en) | 1989-08-02 |
| DE3836343A1 (de) | 1989-06-01 |
| GB8827069D0 (en) | 1988-12-21 |
| NL8802797A (nl) | 1989-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |