CH625231A5 - - Google Patents

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Publication number
CH625231A5
CH625231A5 CH78877A CH78877A CH625231A5 CH 625231 A5 CH625231 A5 CH 625231A5 CH 78877 A CH78877 A CH 78877A CH 78877 A CH78877 A CH 78877A CH 625231 A5 CH625231 A5 CH 625231A5
Authority
CH
Switzerland
Prior art keywords
general formula
reaction
zinc
dihydro
quinazolinone
Prior art date
Application number
CH78877A
Other languages
German (de)
English (en)
Inventor
Michihiro Yamamoto
Shigenari Katayama
Masao Koshiba
Hisao Yamamoto
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of CH625231A5 publication Critical patent/CH625231A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80Oxygen atoms
    • C07D239/82Oxygen atoms with an aryl radical attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH78877A 1976-01-23 1977-01-21 CH625231A5 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP692076A JPS5291885A (en) 1976-01-23 1976-01-23 3,4-dihydro-2(1h)-quinazolinone derivatives

Publications (1)

Publication Number Publication Date
CH625231A5 true CH625231A5 (hu) 1981-09-15

Family

ID=11651662

Family Applications (1)

Application Number Title Priority Date Filing Date
CH78877A CH625231A5 (hu) 1976-01-23 1977-01-21

Country Status (13)

Country Link
US (1) US4048168A (hu)
JP (1) JPS5291885A (hu)
AT (1) AT353276B (hu)
CA (1) CA1069505A (hu)
CH (1) CH625231A5 (hu)
DE (1) DE2702530A1 (hu)
DK (1) DK141064B (hu)
FR (1) FR2338934A1 (hu)
GB (1) GB1525892A (hu)
HU (1) HU174389B (hu)
MX (1) MX3959E (hu)
NL (1) NL7614574A (hu)
SE (1) SE422324B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5271483A (en) * 1975-12-11 1977-06-14 Sumitomo Chem Co Ltd Synthesis of 2(1h)-quinazolinone derivatives
US4282226A (en) * 1978-04-26 1981-08-04 E. R. Squibb & Sons, Inc. Thioxopyrazolo[1,5-c]quinazoline derivatives, anti-allergic compositions and methods for treating allergic conditions by parenteral administration, aerosol or insufflation
EP1394242A3 (en) * 2002-08-07 2004-04-21 Rohm And Haas Company Cyclic thioureas and their use as additives for lubricating oils
CA2513708C (en) * 2003-01-23 2011-01-04 Shire Holdings Ag Formulation and methods for the treatment of thrombocythemia
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3748331A (en) * 1971-05-06 1973-07-24 Sandoz Ag 1,4-disubstituted-methylenedioxy -2-(1h)-quinazolinones and quinazolinthiones

Also Published As

Publication number Publication date
SE422324B (sv) 1982-03-01
AT353276B (de) 1979-11-12
DK141064C (hu) 1980-06-23
DK22277A (hu) 1977-07-24
DE2702530A1 (de) 1977-07-28
CA1069505A (en) 1980-01-08
US4048168A (en) 1977-09-13
SE7700533L (sv) 1977-07-24
HU174389B (hu) 1979-12-28
ATA22777A (de) 1979-04-15
DK141064B (da) 1980-01-07
MX3959E (es) 1981-10-15
FR2338934A1 (fr) 1977-08-19
JPS5291885A (en) 1977-08-02
GB1525892A (en) 1978-09-20
NL7614574A (nl) 1977-07-26
AU2131477A (en) 1978-02-23
FR2338934B1 (hu) 1980-12-19

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Legal Events

Date Code Title Description
PL Patent ceased