CH612913A5 - Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes - Google Patents

Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes

Info

Publication number
CH612913A5
CH612913A5 CH25579A CH25579A CH612913A5 CH 612913 A5 CH612913 A5 CH 612913A5 CH 25579 A CH25579 A CH 25579A CH 25579 A CH25579 A CH 25579A CH 612913 A5 CH612913 A5 CH 612913A5
Authority
CH
Switzerland
Prior art keywords
aralkoxyphenyl
arylalkylamino
alkanes
bis
novel
Prior art date
Application number
CH25579A
Inventor
John E Dr Francis
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CH612913A5 publication Critical patent/CH612913A5/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Abstract

Compounds of the formula I which lower blood pressure and reduce the heart rate <IMAGE> are prepared, in which Ar1, Ar2 and Ar3, Ph, n, m, p, r and R have the meanings stated in claim 1, and their salts. These are obtained by condensing a compound of the general formula (II> Ar1-CmH2m-T (II> in which T denotes a reactive esterified hydroxyl groups, with a compound of the general formula (III> HO-Ph-(CH2)r-CH(CnH2n+1)-NH-CpH2p-CR1(Ar2Ar3 ) (III> or its reactive salts.
CH25579A 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes CH612913A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49494874A 1974-08-05 1974-08-05

Publications (1)

Publication Number Publication Date
CH612913A5 true CH612913A5 (en) 1979-08-31

Family

ID=23966620

Family Applications (5)

Application Number Title Priority Date Filing Date
CH25379A CH612911A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH25279A CH612910A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH993575A CH612909A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH25479A CH612912A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH25579A CH612913A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CH25379A CH612911A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH25279A CH612910A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH993575A CH612909A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes
CH25479A CH612912A5 (en) 1974-08-05 1975-07-30 Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes

Country Status (18)

Country Link
JP (1) JPS5141345A (en)
AT (1) AT340388B (en)
BE (1) BE832082A (en)
CA (1) CA1069923A (en)
CH (5) CH612911A5 (en)
DE (1) DE2534339A1 (en)
DK (1) DK317175A (en)
ES (5) ES439997A1 (en)
FI (1) FI752095A (en)
FR (1) FR2281105A1 (en)
GB (1) GB1504604A (en)
HU (1) HU175581B (en)
IE (1) IE42335B1 (en)
IL (1) IL47813A (en)
NL (1) NL7509270A (en)
NO (1) NO752621L (en)
SE (1) SE7508181L (en)
ZA (2) ZA754192B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5726653A (en) * 1980-05-09 1982-02-12 Ciba Geigy Ag Substituted phenyl ether
US7381750B2 (en) 2004-03-12 2008-06-03 Eli Lilly And Company Amino-phenoxymethyl-benzamide opioid receptor antagonists

Also Published As

Publication number Publication date
AT340388B (en) 1977-12-12
ZA754192B (en) 1976-06-30
IL47813A (en) 1979-07-25
CH612910A5 (en) 1979-08-31
CH612911A5 (en) 1979-08-31
IE42335B1 (en) 1980-07-16
ATA604275A (en) 1977-04-15
BE832082A (en) 1976-02-04
CA1069923A (en) 1980-01-15
NL7509270A (en) 1976-02-09
ES439997A1 (en) 1977-06-16
SE7508181L (en) 1976-02-06
IL47813A0 (en) 1975-10-15
FR2281105A1 (en) 1976-03-05
GB1504604A (en) 1978-03-22
CH612912A5 (en) 1979-08-31
CH612909A5 (en) 1979-08-31
IE42335L (en) 1976-02-05
DK317175A (en) 1976-02-06
ES455489A1 (en) 1978-01-01
AU8362675A (en) 1977-02-10
NO752621L (en) 1976-02-06
JPS5141345A (en) 1976-04-07
HU175581B (en) 1980-09-28
ES455488A1 (en) 1978-01-01
ES455490A1 (en) 1978-01-01
FR2281105B1 (en) 1980-02-08
ES455491A1 (en) 1978-01-01
ZA755018B (en) 1976-07-28
FI752095A (en) 1976-02-06
DE2534339A1 (en) 1976-02-19

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Legal Events

Date Code Title Description
PL Patent ceased