CH612910A5 - Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes - Google Patents
Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanesInfo
- Publication number
- CH612910A5 CH612910A5 CH25279A CH25279A CH612910A5 CH 612910 A5 CH612910 A5 CH 612910A5 CH 25279 A CH25279 A CH 25279A CH 25279 A CH25279 A CH 25279A CH 612910 A5 CH612910 A5 CH 612910A5
- Authority
- CH
- Switzerland
- Prior art keywords
- alkylamino
- mono
- substituted
- aralkoxyphenyl
- arylalkylamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Compounds of the formula I which lower blood pressure and reduce the heart rate <IMAGE> are prepared, in which Ar1, Ar2 and Ar3 are phenyl which is unsubstituted or substituted by one or more lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino, mono-lower-alkylamino or di-lower-alkylamino, lower alkanoylamino, cyano, carboxyl, carbo-lower-alkoxy, carbamoyl, aminomethyl, mono-lower-alkylaminomethyl or di-lower-alkylaminomethyl groups or one or more halogen atoms, Ph is phenylene which can be substituted by one of the substituents mentioned for Ar1, n is 0 to 4, and m and p represent 1 to 4, r is 1 or 2, and R1 is hydrogen or hydroxyl, and their salts. These are obtained by reducing a starting material which corresponds to the above formula, in which at least one of the radicals CmH2m, CnH2n+1 or CpH2p <IMAGE> has a double bond.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49494874A | 1974-08-05 | 1974-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH612910A5 true CH612910A5 (en) | 1979-08-31 |
Family
ID=23966620
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH25279A CH612910A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH25479A CH612912A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH993575A CH612909A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH25379A CH612911A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH25579A CH612913A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH25479A CH612912A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH993575A CH612909A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH25379A CH612911A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
| CH25579A CH612913A5 (en) | 1974-08-05 | 1975-07-30 | Process for the preparation of novel 1-(aralkoxyphenyl)-2- or -3-(bis-arylalkylamino)alkanes |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5141345A (en) |
| AT (1) | AT340388B (en) |
| BE (1) | BE832082A (en) |
| CA (1) | CA1069923A (en) |
| CH (5) | CH612910A5 (en) |
| DE (1) | DE2534339A1 (en) |
| DK (1) | DK317175A (en) |
| ES (5) | ES439997A1 (en) |
| FI (1) | FI752095A (en) |
| FR (1) | FR2281105A1 (en) |
| GB (1) | GB1504604A (en) |
| HU (1) | HU175581B (en) |
| IE (1) | IE42335B1 (en) |
| IL (1) | IL47813A (en) |
| NL (1) | NL7509270A (en) |
| NO (1) | NO752621L (en) |
| SE (1) | SE7508181L (en) |
| ZA (2) | ZA754192B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5726653A (en) * | 1980-05-09 | 1982-02-12 | Ciba Geigy Ag | Substituted phenyl ether |
| WO2005090286A1 (en) * | 2004-03-12 | 2005-09-29 | Eli Lilly And Company | Opioid receptor antagonists |
-
1975
- 1975-07-01 ZA ZA00754192A patent/ZA754192B/en unknown
- 1975-07-11 DK DK317175A patent/DK317175A/en unknown
- 1975-07-17 SE SE7508181A patent/SE7508181L/en unknown
- 1975-07-21 FI FI752095A patent/FI752095A/fi not_active Application Discontinuation
- 1975-07-23 NO NO752621A patent/NO752621L/no unknown
- 1975-07-25 IL IL47813A patent/IL47813A/en unknown
- 1975-07-30 CH CH25279A patent/CH612910A5/en not_active IP Right Cessation
- 1975-07-30 CH CH25479A patent/CH612912A5/en not_active IP Right Cessation
- 1975-07-30 CH CH993575A patent/CH612909A5/en not_active IP Right Cessation
- 1975-07-30 CH CH25379A patent/CH612911A5/en not_active IP Right Cessation
- 1975-07-30 GB GB31893/75A patent/GB1504604A/en not_active Expired
- 1975-07-30 CH CH25579A patent/CH612913A5/en not_active IP Right Cessation
- 1975-08-01 DE DE19752534339 patent/DE2534339A1/en not_active Withdrawn
- 1975-08-01 CA CA232,735A patent/CA1069923A/en not_active Expired
- 1975-08-01 HU HU75CI1597A patent/HU175581B/en unknown
- 1975-08-01 FR FR7524088A patent/FR2281105A1/en active Granted
- 1975-08-01 IE IE1724/75A patent/IE42335B1/en unknown
- 1975-08-04 BE BE158907A patent/BE832082A/en unknown
- 1975-08-04 AT AT604275A patent/AT340388B/en not_active IP Right Cessation
- 1975-08-04 NL NL7509270A patent/NL7509270A/en not_active Application Discontinuation
- 1975-08-04 ZA ZA00755018A patent/ZA755018B/en unknown
- 1975-08-04 ES ES439997A patent/ES439997A1/en not_active Expired
- 1975-08-05 JP JP50094800A patent/JPS5141345A/en active Pending
-
1977
- 1977-01-31 ES ES455491A patent/ES455491A1/en not_active Expired
- 1977-01-31 ES ES455488A patent/ES455488A1/en not_active Expired
- 1977-01-31 ES ES455490A patent/ES455490A1/en not_active Expired
- 1977-01-31 ES ES455489A patent/ES455489A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7509270A (en) | 1976-02-09 |
| AU8362675A (en) | 1977-02-10 |
| ES439997A1 (en) | 1977-06-16 |
| ZA755018B (en) | 1976-07-28 |
| ZA754192B (en) | 1976-06-30 |
| SE7508181L (en) | 1976-02-06 |
| CH612911A5 (en) | 1979-08-31 |
| CA1069923A (en) | 1980-01-15 |
| IL47813A (en) | 1979-07-25 |
| FR2281105B1 (en) | 1980-02-08 |
| GB1504604A (en) | 1978-03-22 |
| FI752095A (en) | 1976-02-06 |
| IE42335B1 (en) | 1980-07-16 |
| NO752621L (en) | 1976-02-06 |
| ES455490A1 (en) | 1978-01-01 |
| FR2281105A1 (en) | 1976-03-05 |
| AT340388B (en) | 1977-12-12 |
| CH612912A5 (en) | 1979-08-31 |
| JPS5141345A (en) | 1976-04-07 |
| BE832082A (en) | 1976-02-04 |
| ES455491A1 (en) | 1978-01-01 |
| DE2534339A1 (en) | 1976-02-19 |
| ES455488A1 (en) | 1978-01-01 |
| HU175581B (en) | 1980-09-28 |
| CH612913A5 (en) | 1979-08-31 |
| ES455489A1 (en) | 1978-01-01 |
| DK317175A (en) | 1976-02-06 |
| ATA604275A (en) | 1977-04-15 |
| IL47813A0 (en) | 1975-10-15 |
| IE42335L (en) | 1976-02-05 |
| CH612909A5 (en) | 1979-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |