CH611898A5 - - Google Patents

Info

Publication number
CH611898A5
CH611898A5 CH735375A CH735375A CH611898A5 CH 611898 A5 CH611898 A5 CH 611898A5 CH 735375 A CH735375 A CH 735375A CH 735375 A CH735375 A CH 735375A CH 611898 A5 CH611898 A5 CH 611898A5
Authority
CH
Switzerland
Application number
CH735375A
Inventor
Emilio Dr Kyburz
Werner Aschwanden
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH735375A priority Critical patent/CH611898A5/xx
Priority to CH44079A priority patent/CH613205A5/xx
Priority to IL49439A priority patent/IL49439A/xx
Priority to ZA762358A priority patent/ZA762358B/xx
Priority to NZ180658A priority patent/NZ180658A/xx
Priority to AU13423/76A priority patent/AU499937B2/en
Priority to FI761411A priority patent/FI761411A/fi
Priority to HU76HO1906A priority patent/HU173216B/hu
Priority to US05/690,325 priority patent/US4089861A/en
Priority to MC761198A priority patent/MC1105A1/xx
Priority to IE1155/76A priority patent/IE44228B1/en
Priority to JP51064173A priority patent/JPS51146487A/ja
Priority to DK244876A priority patent/DK244876A/da
Priority to AT409376A priority patent/AT355026B/de
Priority to PL1976190139A priority patent/PL103423B1/pl
Priority to DE19762625258 priority patent/DE2625258A1/de
Priority to GB23182/76A priority patent/GB1546241A/en
Priority to SE7606387A priority patent/SE7606387L/xx
Priority to DD193199A priority patent/DD125779A6/xx
Priority to NL7606088A priority patent/NL7606088A/xx
Priority to PL21068476A priority patent/PL107264B1/pl
Priority to LU75091A priority patent/LU75091A1/xx
Priority to CA254,151A priority patent/CA1069506A/en
Priority to GR50894A priority patent/GR60451B7/el
Priority to FR7617013A priority patent/FR2313062A2/fr
Priority to BE167620A priority patent/BE842593R/xx
Priority to NO761896A priority patent/NO761896L/no
Priority to SU762365997A priority patent/SU637085A3/ru
Priority to ES448609A priority patent/ES448609A2/es
Priority to AR266794A priority patent/AR211168A1/es
Priority to SU772463802A priority patent/SU633480A3/ru
Priority to AT518377A priority patent/AT355031B/de
Publication of CH611898A5 publication Critical patent/CH611898A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH735375A 1973-03-30 1975-06-06 CH611898A5 (el)

Priority Applications (32)

Application Number Priority Date Filing Date Title
CH735375A CH611898A5 (el) 1975-06-06 1975-06-06
CH44079A CH613205A5 (el) 1975-06-06 1975-06-06
IL49439A IL49439A (en) 1975-04-11 1976-04-19 3-2-4-8fluoro-10,11dihydro-2-methyldibenzo thiepin -10-yl-piperazinylethyl-2-oxazolikinone,its manufacture and pharmaceutical compositions containing it
ZA762358A ZA762358B (en) 1975-06-06 1976-04-21 Dibenzo(b,f)thiepin derivative
NZ180658A NZ180658A (en) 1975-06-06 1976-04-22 Enantiomers of 3-(2-4-(8-fluoro-10,11-dihydro-2-methyldibenzo(b,f)thiepin-10-yl)-1-piperazinyl- -ethyl)-2-oxazolidinone
AU13423/76A AU499937B2 (en) 1975-06-06 1976-04-28 DIBENZO / b, f / THIEPIN DERIVATIVES
FI761411A FI761411A (el) 1975-06-06 1976-05-19
HU76HO1906A HU173216B (hu) 1975-06-06 1976-05-20 Sposob poluchenija proizvodnogo dibenzo/b,f/tiehpina
US05/690,325 US4089861A (en) 1975-06-06 1976-05-26 (+)-(S)-Enantiomer of 3-{2-[4-(8-fluoro-10,11-dihydro-2-methyl-dibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-ethyl}-2-oxazolidinone
MC761198A MC1105A1 (fr) 1975-06-06 1976-05-31 Derive de dibenzo(b,f)thiepine
IE1155/76A IE44228B1 (en) 1975-06-06 1976-05-31 A 3-/2-/4(10,11-dihydro-dibenzo/b,f/thiepin-10-yl)-1-piperazinyl/-ethyl/-2-oxazolidinone and salts thereof
JP51064173A JPS51146487A (en) 1975-06-06 1976-06-03 Optically active dibenzo *b*f* thiepines
DK244876A DK244876A (da) 1975-06-06 1976-06-03 Dibenzo (b,f)thiepinderivater deres fremstilling og anvendelse
AT409376A AT355026B (de) 1975-06-06 1976-06-03 Verfahren zur herstellung des (+)-(s)- enantiomeren von 3-(2-(4-(8-fluor-10,11- -dihydro-2-methyl-dibenzo(b,f)-thiepin- 10-yl)-1-piperazinyl)-aethyl)-2-oxazolidinon und dessen salzen
PL1976190139A PL103423B1 (pl) 1975-06-06 1976-06-04 Sposob wytwarzania enancjomeru/+/-/s/-3-(2-/4-/8-fluoro-10,11-dwuwodoro-2-metylo-dwubezo/b,f/tiepin-10-ylo/-1-piperazynylo/-etylo)-oksazolidynonu-2 i jego soli
DE19762625258 DE2625258A1 (de) 1975-06-06 1976-06-04 Dibenzo eckige klammer auf b,f eckige klammer zu thiepinderivat
GB23182/76A GB1546241A (en) 1975-06-06 1976-06-04 3-(2-(4(10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazinyl)-ethyl)-2-oxazolidinone and salts thereof
SE7606387A SE7606387L (sv) 1975-06-06 1976-06-04 Dibenso/b,f/tiepinderivat
DD193199A DD125779A6 (el) 1975-06-06 1976-06-04
NL7606088A NL7606088A (en) 1973-03-30 1976-06-04 3-(4-(Dibenzothiepinyl) 1-piperazinyl alkyl) oxazolidinones - specific enantiomers useful as neuroleptics and CNS depressants (BE061276)
PL21068476A PL107264B1 (pl) 1975-06-06 1976-06-04 Sposob wytwarzania/+/-/s/-3-/2-/4-18-fluoro-10,11-dwuwodoro-2-metylodwubenzo/b,f/tiepin-10-ylo/-1-piperazynylo/-etylo/-oksazolidynonu-2
LU75091A LU75091A1 (el) 1975-06-06 1976-06-04
CA254,151A CA1069506A (en) 1975-06-06 1976-06-04 Dibenzo (b,f) thiepin derivative
GR50894A GR60451B7 (en) 1974-03-28 1976-06-04 Preparation process of dibenzo(b,f)thiepin derivatives
FR7617013A FR2313062A2 (fr) 1975-06-06 1976-06-04 Derive de dibenzo b,f thiepine
BE167620A BE842593R (fr) 1975-06-06 1976-06-04 Composes tricycliques
NO761896A NO761896L (el) 1975-06-06 1976-06-04
SU762365997A SU637085A3 (ru) 1975-06-06 1976-06-04 Способ получени /+/-/ /энантиомера 3- 2- 4-(8-фтор-10,11-дигидро-2-метил-дибензо( )тиепин-10-ил) -1-пиперазинил -этил -2-оксазолидинона или его солей
ES448609A ES448609A2 (es) 1975-06-06 1976-06-05 Procedimiento para la preparacion de compuestos triciclicos derivados de dibenzo (b,f)tiepina.
AR266794A AR211168A1 (es) 1975-06-06 1977-03-09 Procedimiento para la preparacion de dibenco (b,f) tiepina opticamente activa y sales de la misma.
SU772463802A SU633480A3 (ru) 1975-06-06 1977-03-25 Способ получени (+) - ( )-энантиомера 3-12-/4-(8-фтор-10,11-дигидро-2метилдибензо тиепин-10-ил)-1-пиперазинил/-этил-2-оксазолидинова или его солей
AT518377A AT355031B (de) 1975-06-06 1977-07-18 Verfahren zur herstellung des (+)-(s)- enantiomeren von3-(2-(4-(8-fluor-10,11-dihydro- 2-methyl-dibenzo(b,f)-thiepin-10-yl)-1- piperazinyl)-aethyl)-2-oxa-zolidinon und dessen salzen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH735375A CH611898A5 (el) 1975-06-06 1975-06-06
CH350676 1976-03-19

Publications (1)

Publication Number Publication Date
CH611898A5 true CH611898A5 (el) 1979-06-29

Family

ID=25693196

Family Applications (2)

Application Number Title Priority Date Filing Date
CH44079A CH613205A5 (el) 1975-06-06 1975-06-06
CH735375A CH611898A5 (el) 1973-03-30 1975-06-06

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH44079A CH613205A5 (el) 1975-06-06 1975-06-06

Country Status (21)

Country Link
US (1) US4089861A (el)
JP (1) JPS51146487A (el)
AR (1) AR211168A1 (el)
AT (1) AT355026B (el)
AU (1) AU499937B2 (el)
BE (1) BE842593R (el)
CA (1) CA1069506A (el)
CH (2) CH613205A5 (el)
DD (1) DD125779A6 (el)
DK (1) DK244876A (el)
FI (1) FI761411A (el)
FR (1) FR2313062A2 (el)
GB (1) GB1546241A (el)
HU (1) HU173216B (el)
IE (1) IE44228B1 (el)
LU (1) LU75091A1 (el)
MC (1) MC1105A1 (el)
NO (1) NO761896L (el)
PL (1) PL103423B1 (el)
SE (1) SE7606387L (el)
SU (1) SU637085A3 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01149775A (ja) * 1987-12-07 1989-06-12 Kawaken Fine Chem Co Ltd 光学活性２−メチルピペラジンの製造方法
KR100389151B1 (ko) * 1994-04-22 2003-10-04 고에이 가가쿠 고교 가부시키가이샤 광학활성N-tert-부틸-2-피페라진카르복시아미드의제조방법및그라세미화법
EP0988295A4 (en) * 1997-06-18 2003-08-13 Synaptic Pharma Corp HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF
US6159990A (en) * 1997-06-18 2000-12-12 Synaptic Pharmaceutical Corporation Oxazolidinones as α1A receptor antagonists
US6319932B1 (en) 1998-11-10 2001-11-20 Merck & Co., Inc. Oxazolidinones useful as alpha 1A adrenoceptor antagonists
US6228870B1 (en) 1998-11-10 2001-05-08 Merck & Co., Inc. Oxazolidinones useful as alpha 1a adrenoceptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD113545A5 (el) * 1973-03-30 1975-06-12
US3954769A (en) * 1973-03-30 1976-05-04 Hoffman-La Roche Inc. Dibenzo[b,f]thiepins
DE2412520C2 (de) * 1973-03-30 1982-09-16 F. Hoffmann-La Roche & Co. AG, 4002 Basel Tricyclische Verbindungen, Verfahren zu deren Herstellung und diese enthaltende Präparate
US3954764A (en) * 1973-03-30 1976-05-04 Hoffmann-La Roche Inc. Dibenzo [b,f]thiepins bearing piperazinyl substitution

Also Published As

Publication number Publication date
FR2313062A2 (fr) 1976-12-31
NO761896L (el) 1976-12-07
CH613205A5 (el) 1979-09-14
IE44228L (en) 1976-12-06
AT355026B (de) 1980-02-11
AU499937B2 (en) 1979-05-03
JPS51146487A (en) 1976-12-16
DD125779A6 (el) 1977-05-18
GB1546241A (en) 1979-05-23
ATA409376A (de) 1979-07-15
PL103423B1 (pl) 1979-06-30
SU637085A3 (ru) 1978-12-05
LU75091A1 (el) 1978-01-18
MC1105A1 (fr) 1977-02-04
SE7606387L (sv) 1976-12-07
FR2313062B2 (el) 1978-12-15
BE842593R (fr) 1976-12-06
CA1069506A (en) 1980-01-08
HU173216B (hu) 1979-03-28
DK244876A (da) 1976-12-07
FI761411A (el) 1976-12-07
US4089861A (en) 1978-05-16
IE44228B1 (en) 1981-09-23
AR211168A1 (es) 1977-10-31
AU1342376A (en) 1977-11-03

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Legal Events

Date Code Title Description
PL Patent ceased