CH587858A5 - - Google Patents

Info

Publication number
CH587858A5
CH587858A5 CH1669873A CH1669873A CH587858A5 CH 587858 A5 CH587858 A5 CH 587858A5 CH 1669873 A CH1669873 A CH 1669873A CH 1669873 A CH1669873 A CH 1669873A CH 587858 A5 CH587858 A5 CH 587858A5
Authority
CH
Switzerland
Application number
CH1669873A
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH1669873A priority Critical patent/CH587858A5/xx
Priority to DE19742454619 priority patent/DE2454619A1/de
Priority to FI3345/74A priority patent/FI59254C/fi
Priority to DK600374A priority patent/DK143804C/da
Priority to SE7414607A priority patent/SE417319B/xx
Priority to NO744175A priority patent/NO744175L/no
Priority to NL7415250A priority patent/NL7415250A/xx
Priority to GB23690/77A priority patent/GB1496492A/en
Priority to GB50914/74A priority patent/GB1496491A/en
Priority to CS8081A priority patent/CS176291B2/cs
Priority to HUSA2719A priority patent/HU168859B/hu
Priority to IE2432/74A priority patent/IE41767B1/en
Priority to IL46128A priority patent/IL46128A/en
Priority to AT945174A priority patent/AT352911B/de
Priority to PH16563A priority patent/PH13669A/en
Priority to ES432288A priority patent/ES432288A1/es
Priority to DD182581A priority patent/DD115119A5/xx
Priority to AU75826/74A priority patent/AU492554B2/en
Priority to JP49135657A priority patent/JPS5919116B2/ja
Priority to CA214,716A priority patent/CA1034572A/en
Priority to SU2082566A priority patent/SU516355A3/ru
Priority to ZA00747603A priority patent/ZA747603B/xx
Priority to FR7439049A priority patent/FR2252098B1/fr
Priority to BE150971A priority patent/BE822729A/xx
Priority to FR7702636A priority patent/FR2334681A1/fr
Publication of CH587858A5 publication Critical patent/CH587858A5/xx
Priority to SE7710418A priority patent/SE424869B/xx
Priority to AT1878A priority patent/AT368154B/de
Priority to US05/920,480 priority patent/US4229451A/en
Priority to DK217979A priority patent/DK146564C/da
Priority to HK540/80A priority patent/HK54080A/xx
Priority to MY185/81A priority patent/MY8100185A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
CH1669873A 1973-11-28 1973-11-28 CH587858A5 (zh)

Priority Applications (31)

Application Number Priority Date Filing Date Title
CH1669873A CH587858A5 (zh) 1973-11-28 1973-11-28
DE19742454619 DE2454619A1 (de) 1973-11-28 1974-11-18 Verfahren zur herstellung neuer heterocyclischer verbindungen
FI3345/74A FI59254C (fi) 1973-11-28 1974-11-19 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergopeptinderivat
DK600374A DK143804C (da) 1973-11-28 1974-11-19 Analogifremgangsmaade til fremstilling af ergopeptinderivater
SE7414607A SE417319B (sv) 1973-11-28 1974-11-20 Analogiforfarande for framstellning av ergopeptiner
NO744175A NO744175L (zh) 1973-11-28 1974-11-20
NL7415250A NL7415250A (nl) 1973-11-28 1974-11-22 Werkwijze voor de bereiding van ergopeptine- derivaten.
GB23690/77A GB1496492A (en) 1973-11-28 1974-11-25 Optically active lysergic acid derivatives
GB50914/74A GB1496491A (en) 1973-11-28 1974-11-25 Dihydroergopeptine derivatives
ES432288A ES432288A1 (es) 1973-11-28 1974-11-26 Procedimiento para preparar derivados de ergopectina.
HUSA2719A HU168859B (zh) 1973-11-28 1974-11-26
IE2432/74A IE41767B1 (en) 1973-11-28 1974-11-26 Dihydroergopeptine derivatives
IL46128A IL46128A (en) 1973-11-28 1974-11-26 Lysergic acid derivatives their production and pharmaceutical compositions containing them
AT945174A AT352911B (de) 1973-11-28 1974-11-26 Verfahren zur herstellung neuer ergopeptin- derivate
PH16563A PH13669A (en) 1973-11-28 1974-11-26 6-nor-6-isopropyl-9,10-dihydro-2'beta-methyl-5'alpha-benzyl-ergopetine
CS8081A CS176291B2 (zh) 1973-11-28 1974-11-26
DD182581A DD115119A5 (zh) 1973-11-28 1974-11-26
AU75826/74A AU492554B2 (en) 1973-11-28 1974-11-27 6-alkyl-9,10-dihydro-2' b-methyl-5'-benzyl-ergopeptide derivatives
JP49135657A JPS5919116B2 (ja) 1973-11-28 1974-11-27 複素環式化合物の製造法
CA214,716A CA1034572A (en) 1973-11-28 1974-11-27 6-NOR-6-ALKYL-9,10-DIHYDRO-2'.beta.-METHYL-5'.alpha.-BENZYL-ERGOPEPTINE
SU2082566A SU516355A3 (ru) 1973-11-28 1974-11-28 Способ получени производных 9,10-дигидро-лизергиновой кислоты
ZA00747603A ZA747603B (en) 1973-11-28 1974-11-28 Improvements in or relating to organic compounds
FR7439049A FR2252098B1 (zh) 1973-11-28 1974-11-28
BE150971A BE822729A (fr) 1973-11-28 1974-11-28 Nouveaux derives de l'acide lysergique
FR7702636A FR2334681A1 (fr) 1973-11-28 1977-01-31 Nouveaux derives de l'acide lysergique et leur preparation
SE7710418A SE424869B (sv) 1973-11-28 1977-09-16 Mellanprodukt for framstellning av farmakodynamiskt verksamma 6-nor-6-alkyl-ergolinderivat
AT1878A AT368154B (de) 1973-11-28 1978-01-03 Verfahren zur herstellung neuer lysergsaeurederivate
US05/920,480 US4229451A (en) 1973-11-28 1978-06-29 Ergopeptine derivatives
DK217979A DK146564C (da) 1973-11-28 1979-05-25 Lysergsyrederivater
HK540/80A HK54080A (en) 1973-11-28 1980-09-25 Dihydroergopeptine derivatives
MY185/81A MY8100185A (en) 1973-11-28 1981-12-30 Dihydroergopeptine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1669873A CH587858A5 (zh) 1973-11-28 1973-11-28

Publications (1)

Publication Number Publication Date
CH587858A5 true CH587858A5 (zh) 1977-05-13

Family

ID=4419482

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1669873A CH587858A5 (zh) 1973-11-28 1973-11-28

Country Status (25)

Country Link
US (1) US4229451A (zh)
JP (1) JPS5919116B2 (zh)
AT (1) AT352911B (zh)
BE (1) BE822729A (zh)
CA (1) CA1034572A (zh)
CH (1) CH587858A5 (zh)
CS (1) CS176291B2 (zh)
DD (1) DD115119A5 (zh)
DE (1) DE2454619A1 (zh)
DK (1) DK143804C (zh)
ES (1) ES432288A1 (zh)
FI (1) FI59254C (zh)
FR (2) FR2252098B1 (zh)
GB (2) GB1496492A (zh)
HK (1) HK54080A (zh)
HU (1) HU168859B (zh)
IE (1) IE41767B1 (zh)
IL (1) IL46128A (zh)
MY (1) MY8100185A (zh)
NL (1) NL7415250A (zh)
NO (1) NO744175L (zh)
PH (1) PH13669A (zh)
SE (2) SE417319B (zh)
SU (1) SU516355A3 (zh)
ZA (1) ZA747603B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601321A5 (zh) * 1975-01-06 1978-07-14 Sandoz Ag
CH619468A5 (zh) * 1976-01-12 1980-09-30 Sandoz Ag
DE3020895A1 (de) * 1979-06-12 1980-12-18 Sandoz Ag Ergopeptinderivate, verfahren zu deren herstellung sowie diese ergopeptinderivate enthaltende pharmazeutischen zusammensetzungen
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
US20070197576A1 (en) * 2006-02-08 2007-08-23 Resolution Chemicals Limited Production of Cabergoline and Novel Polymorphic Form Thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2619488A (en) * 1952-11-25 Method of preparing d
GB769260A (en) * 1954-04-07 1957-03-06 Sandoz Ltd Process for the preparation of isomeric racemic dihydrolysergic acids and their homologues
DE1006425B (de) * 1954-04-07 1957-04-18 Sandoz Ag Verfahren zur Herstellung der isomeren racemischen Dihydrolysergsaeuren und ihren Homologen
GB1011112A (en) * 1961-05-10 1965-11-24 Sandoz Ag Improvements in or relating to ergot alkaloids
CH469006A (de) * 1965-07-07 1969-02-28 Sandoz Ag Verfahren zur Herstellung neuer synthetischer Alkaloide
CH469735A (de) * 1965-11-02 1969-03-15 Sandoz Ag Verfahren zur Herstellung heterocyclischer Verbindungen
GB1298277A (en) * 1969-04-18 1972-11-29 Sandoz Ltd Preparation of ergot peptide alkaloids
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CH601321A5 (zh) * 1975-01-06 1978-07-14 Sandoz Ag
US4138565A (en) * 1975-05-31 1979-02-06 Sandoz Ltd. Stable solutions and processes for their preparation

Also Published As

Publication number Publication date
SE7414607L (zh) 1975-05-29
NO744175L (zh) 1975-06-23
PH13669A (en) 1980-08-26
SE424869B (sv) 1982-08-16
JPS5919116B2 (ja) 1984-05-02
DD115119A5 (zh) 1975-09-12
MY8100185A (en) 1981-12-31
FR2334681B1 (zh) 1980-04-18
FI59254C (fi) 1981-07-10
FR2252098A1 (zh) 1975-06-20
FI334574A (zh) 1975-05-29
FR2334681A1 (fr) 1977-07-08
DK143804C (da) 1982-03-29
NL7415250A (nl) 1975-05-30
JPS5084599A (zh) 1975-07-08
GB1496491A (en) 1977-12-30
DE2454619A1 (de) 1975-06-05
SE417319B (sv) 1981-03-09
AT352911B (de) 1979-10-10
DK600374A (zh) 1975-07-28
HU168859B (zh) 1976-07-28
IE41767B1 (en) 1980-03-26
CS176291B2 (zh) 1977-06-30
DK143804B (da) 1981-10-12
FR2252098B1 (zh) 1978-06-30
GB1496492A (en) 1977-12-30
ES432288A1 (es) 1977-02-16
SE7710418L (sv) 1977-09-16
ZA747603B (en) 1976-07-28
IL46128A0 (en) 1975-02-10
IL46128A (en) 1977-10-31
CA1034572A (en) 1978-07-11
FI59254B (fi) 1981-03-31
ATA945174A (de) 1979-03-15
US4229451A (en) 1980-10-21
BE822729A (fr) 1975-05-28
IE41767L (en) 1975-05-28
HK54080A (en) 1980-10-03
AU7582674A (en) 1976-05-27
SU516355A3 (ru) 1976-05-30

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Legal Events

Date Code Title Description
PL Patent ceased