CH558374A - Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten. - Google Patents

Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.

Info

Publication number
CH558374A
CH558374A CH450074A CH450074A CH558374A CH 558374 A CH558374 A CH 558374A CH 450074 A CH450074 A CH 450074A CH 450074 A CH450074 A CH 450074A CH 558374 A CH558374 A CH 558374A
Authority
CH
Switzerland
Prior art keywords
chinazolone
alkenyl
aryl
derivatives
production
Prior art date
Application number
CH450074A
Other languages
German (de)
English (en)
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of CH558374A publication Critical patent/CH558374A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH450074A 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten. CH558374A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702027645 DE2027645A1 (de) 1970-06-05 1970-06-05 Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CH558374A true CH558374A (de) 1975-01-31

Family

ID=5773104

Family Applications (3)

Application Number Title Priority Date Filing Date
CH450174A CH569732A5 (xx) 1970-06-05 1971-06-02
CH802071A CH557829A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.
CH450074A CH558374A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH450174A CH569732A5 (xx) 1970-06-05 1971-06-02
CH802071A CH557829A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.

Country Status (10)

Country Link
US (1) US3984555A (xx)
AT (3) AT317899B (xx)
BE (1) BE768137A (xx)
CA (1) CA951319A (xx)
CH (3) CH569732A5 (xx)
DE (1) DE2027645A1 (xx)
FR (1) FR2100726B1 (xx)
GB (1) GB1331522A (xx)
LU (1) LU63267A1 (xx)
NL (1) NL7107695A (xx)

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US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US6723727B1 (en) * 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
EP0903344B1 (en) * 1997-08-21 2011-01-26 Shiseido Co., Ltd. Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin
US6355637B1 (en) 1999-10-01 2002-03-12 Advanced Medicine, Inc. Local anesthetic compounds
NZ522076A (en) * 2000-04-25 2005-08-26 Icos Corp Inhibitors of human phosphatidyl-inositol 3-kinase delta
US6667300B2 (en) 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
AUPR201600A0 (en) * 2000-12-11 2001-01-11 Fujisawa Pharmaceutical Co., Ltd. Quinazolinone derivative
US8349853B2 (en) 2001-09-05 2013-01-08 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer
JP2005501887A (ja) * 2001-09-05 2005-01-20 ミナーヴァ・バイオテクノロジーズ・コーポレーション 癌の処置における組成物およびその使用
US7060705B2 (en) 2001-11-07 2006-06-13 Merck & Co., Inc. Mitotic kinesin inhibitors
AUPS019702A0 (en) * 2002-01-29 2002-02-21 Fujisawa Pharmaceutical Co., Ltd. Condensed heterocyclic compounds
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
EP1558260A4 (en) * 2002-11-04 2006-10-25 Nps Pharma Inc CHINAZOLINONE COMPOUNDS AS CALCILYTIC
DE602004022819D1 (de) * 2003-06-06 2009-10-08 Vertex Pharma Von atp-bindende kassette transportern
US20050043239A1 (en) * 2003-08-14 2005-02-24 Jason Douangpanya Methods of inhibiting immune responses stimulated by an endogenous factor
US20050054614A1 (en) * 2003-08-14 2005-03-10 Diacovo Thomas G. Methods of inhibiting leukocyte accumulation
LT2612862T (lt) 2004-05-13 2017-01-25 Icos Corporation Chinazolinonai kaip žmogaus fosfatidilinozitol-3-kinazės delta inhibitoriai
WO2005117889A1 (en) * 2004-05-25 2005-12-15 Icos Corporation Methods for treating and/or preventing aberrant proliferation of hematopoietic
CA2598409A1 (en) * 2005-02-17 2006-08-24 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
US8349850B2 (en) 2006-03-28 2013-01-08 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
JP5794919B2 (ja) 2008-11-13 2015-10-14 ギリアード カリストガ エルエルシー 血液学的な悪性疾患のための療法
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
CN102439012A (zh) 2009-03-24 2012-05-02 吉里德卡利斯托加公司 2-嘌呤基-3-甲苯基-喹唑啉酮衍生物的阻转异构体和使用方法
US8546409B2 (en) * 2009-04-20 2013-10-01 Gilead Calistoga Llc Methods of treatment for solid tumors
JP2013500257A (ja) 2009-07-21 2013-01-07 ギリアード カリストガ エルエルシー Ｐｉ３ｋインヒビターでの肝障害の処置
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
US9353067B2 (en) 2011-04-10 2016-05-31 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
CA2864305C (en) 2012-03-05 2021-02-16 Gilead Calistoga Llc Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
AU2013288265B2 (en) 2012-07-09 2017-04-06 Lupin Limited Tetrahydroquinazolinone derivatives as PARP inhibitors
US9567337B2 (en) 2013-12-20 2017-02-14 Gilead Calistoga Llc Process methods for phosphatidylinositol 3-kinase inhibitors
WO2015095605A1 (en) 2013-12-20 2015-06-25 Gilead Calistoga Llc Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
WO2015191726A1 (en) 2014-06-13 2015-12-17 Gilead Sciences, Inc. Phosphatidylinositol 3-kinase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053063A (xx) * 1963-05-18

Also Published As

Publication number Publication date
US3984555A (en) 1976-10-05
AT318628B (de) 1974-11-11
CH557829A (de) 1975-01-15
CH569732A5 (xx) 1975-11-28
FR2100726A1 (xx) 1972-03-24
LU63267A1 (xx) 1972-08-23
AT318615B (de) 1974-11-11
FR2100726B1 (xx) 1975-10-10
CA951319A (en) 1974-07-16
NL7107695A (xx) 1971-12-07
AT317899B (de) 1974-09-25
GB1331522A (en) 1973-09-26
BE768137A (fr) 1971-12-06
DE2027645A1 (de) 1971-12-09

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Legal Events

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