CH557829A - Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten. - Google Patents

Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.

Info

Publication number
CH557829A
CH557829A CH802071A CH802071A CH557829A CH 557829 A CH557829 A CH 557829A CH 802071 A CH802071 A CH 802071A CH 802071 A CH802071 A CH 802071A CH 557829 A CH557829 A CH 557829A
Authority
CH
Switzerland
Prior art keywords
chinazolone
alkenyl
aryl
derivatives
alkyl
Prior art date
Application number
CH802071A
Other languages
German (de)
English (en)
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of CH557829A publication Critical patent/CH557829A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH802071A 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten. CH557829A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702027645 DE2027645A1 (de) 1970-06-05 1970-06-05 Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CH557829A true CH557829A (de) 1975-01-15

Family

ID=5773104

Family Applications (3)

Application Number Title Priority Date Filing Date
CH450074A CH558374A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.
CH450174A CH569732A5 (xx) 1970-06-05 1971-06-02
CH802071A CH557829A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH450074A CH558374A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.
CH450174A CH569732A5 (xx) 1970-06-05 1971-06-02

Country Status (10)

Country Link
US (1) US3984555A (xx)
AT (3) AT318615B (xx)
BE (1) BE768137A (xx)
CA (1) CA951319A (xx)
CH (3) CH558374A (xx)
DE (1) DE2027645A1 (xx)
FR (1) FR2100726B1 (xx)
GB (1) GB1331522A (xx)
LU (1) LU63267A1 (xx)
NL (1) NL7107695A (xx)

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US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US6723727B1 (en) * 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
EP0903344B1 (en) * 1997-08-21 2011-01-26 Shiseido Co., Ltd. Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin
WO2001025234A1 (en) * 1999-10-01 2001-04-12 Advanced Medicine, Inc. Quinazolinones and analogues and their use as local anesthetics
US6667300B2 (en) * 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
KR100785363B1 (ko) * 2000-04-25 2007-12-18 이코스 코포레이션 인간 포스파티딜-이노시톨 3-키나제 델타의 억제제
AUPR201600A0 (en) * 2000-12-11 2001-01-11 Fujisawa Pharmaceutical Co., Ltd. Quinazolinone derivative
WO2003020280A2 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and use thereof in the treatment of cancer
ATE469648T1 (de) 2001-09-05 2010-06-15 Minerva Biotechnologies Corp Zusammensetzungen und deren verwendung zur behandlung von krebs
AU2002363429B2 (en) * 2001-11-07 2008-05-08 Merck & Co., Inc. Mitotic kinesin inhibitors
AUPS019702A0 (en) * 2002-01-29 2002-02-21 Fujisawa Pharmaceutical Co., Ltd. Condensed heterocyclic compounds
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
WO2004041755A2 (en) * 2002-11-04 2004-05-21 Nps Pharmaceuticals, Inc. Quinazolinone compounds as calcilytics
WO2004111014A1 (en) * 2003-06-06 2004-12-23 Vertex Pharmaceuticals Incorporated Pyrimidine derivatives as modulators of atp-binding cassette transporters
WO2005016348A1 (en) * 2003-08-14 2005-02-24 Icos Corporation Method of inhibiting immune responses stimulated by an endogenous factor
US20050054614A1 (en) * 2003-08-14 2005-03-10 Diacovo Thomas G. Methods of inhibiting leukocyte accumulation
CA2566609C (en) 2004-05-13 2012-06-26 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
CA2567883A1 (en) * 2004-05-25 2005-12-15 Icos Corporation Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
EP1885356A2 (en) * 2005-02-17 2008-02-13 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
WO2007110868A2 (en) * 2006-03-28 2007-10-04 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
NZ611764A (en) 2008-11-13 2015-01-30 Gilead Calistoga Llc Therapies for hematologic malignancies
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
EA019499B1 (ru) 2009-03-24 2014-04-30 ГИЛИЭД КАЛИСТОГА ЭлЭлСи Производные атропоизомеров 2-пуринил-3-толилхиназолинона и способы применения
SG175259A1 (en) * 2009-04-20 2011-11-28 Gilead Calistoga Llc Methods of treatment for solid tumors
WO2011011550A1 (en) 2009-07-21 2011-01-27 Calistoga Pharmaceuticals Inc. Treatment of liver disorders with pi3k inhibitors
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
US9353067B2 (en) 2011-04-10 2016-05-31 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
WO2013134288A1 (en) 2012-03-05 2013-09-12 Gilead Calistoga Llc Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
US9359367B2 (en) 2012-07-09 2016-06-07 Lupin Limited Tetrahydroquinazolinone derivatives as PARP inhibitors
JP2017502021A (ja) 2013-12-20 2017-01-19 ギリアード カリストガ エルエルシー ホスファチジルイノシトール3−キナーゼ阻害剤のためのプロセス方法
JP2017500319A (ja) 2013-12-20 2017-01-05 ギリアード カリストガ エルエルシー (s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態
CA2952012A1 (en) 2014-06-13 2015-12-17 Gilead Sciences, Inc. Phosphatidylinositol 3-kinase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053063A (xx) * 1963-05-18

Also Published As

Publication number Publication date
AT318615B (de) 1974-11-11
FR2100726B1 (xx) 1975-10-10
DE2027645A1 (de) 1971-12-09
US3984555A (en) 1976-10-05
CA951319A (en) 1974-07-16
CH569732A5 (xx) 1975-11-28
BE768137A (fr) 1971-12-06
NL7107695A (xx) 1971-12-07
GB1331522A (en) 1973-09-26
CH558374A (de) 1975-01-31
FR2100726A1 (xx) 1972-03-24
AT317899B (de) 1974-09-25
LU63267A1 (xx) 1972-08-23
AT318628B (de) 1974-11-11

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Legal Events

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