CH542177A - Procédé de préparation d'amino-alcools et de leurs sels - Google Patents

Procédé de préparation d'amino-alcools et de leurs sels

Info

Publication number
CH542177A
CH542177A CH1452070A CH1452070A CH542177A CH 542177 A CH542177 A CH 542177A CH 1452070 A CH1452070 A CH 1452070A CH 1452070 A CH1452070 A CH 1452070A CH 542177 A CH542177 A CH 542177A
Authority
CH
Switzerland
Prior art keywords
sep
ch3s
hcl
ether
meoh
Prior art date
Application number
CH1452070A
Other languages
English (en)
French (fr)
Inventor
P Buu-Hoi Nguyen
Lambelin Georges
Roba Joseph
Jacques Guy
Gillet Claude
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of CH542177A publication Critical patent/CH542177A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
CH1452070A 1969-10-01 1970-10-01 Procédé de préparation d'amino-alcools et de leurs sels CH542177A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE79767 1969-10-01
BE93537 1970-09-03

Publications (1)

Publication Number Publication Date
CH542177A true CH542177A (fr) 1973-09-30

Family

ID=25647478

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1452070A CH542177A (fr) 1969-10-01 1970-10-01 Procédé de préparation d'amino-alcools et de leurs sels

Country Status (17)

Country Link
JP (1) JPS541693B1 (US08066781-20111129-C00013.png)
AR (1) AR194457A1 (US08066781-20111129-C00013.png)
AT (1) AT323135B (US08066781-20111129-C00013.png)
CA (1) CA953723A (US08066781-20111129-C00013.png)
CH (1) CH542177A (US08066781-20111129-C00013.png)
CS (1) CS191158B2 (US08066781-20111129-C00013.png)
DK (1) DK147853C (US08066781-20111129-C00013.png)
FI (1) FI52714C (US08066781-20111129-C00013.png)
FR (1) FR2070102A1 (US08066781-20111129-C00013.png)
HU (1) HU167354B (US08066781-20111129-C00013.png)
IE (1) IE34545B1 (US08066781-20111129-C00013.png)
NL (1) NL156688B (US08066781-20111129-C00013.png)
NO (1) NO132865C (US08066781-20111129-C00013.png)
OA (1) OA03659A (US08066781-20111129-C00013.png)
SE (1) SE384855B (US08066781-20111129-C00013.png)
SU (1) SU578860A3 (US08066781-20111129-C00013.png)
YU (1) YU35580B (US08066781-20111129-C00013.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386029A (en) * 1972-03-20 1975-03-05 Smithkline Corp Alpha-benzylamino-4-benzyloxy-3-alkylsulphonylmethyl phenones
EP0003732B1 (en) * 1978-02-01 1983-10-19 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
GB2067187B (en) * 1979-12-07 1983-11-30 Cosmos Enterprise Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid addition salts thereof
FR2503705A1 (fr) * 1981-04-14 1982-10-15 Synthelabo Derives de phenethanolamine, leur preparation et leur application en therapeutique
FR2508445A1 (fr) * 1981-06-29 1982-12-31 Sori Soc Rech Ind Nouveaux derives de benzoyl-phenyl-piperidine, leur procede de preparation et leur application, notamment en therapeutique
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
FR2537132B1 (fr) * 1982-12-06 1987-01-09 Lafon Labor Nouveaux derives soufres de 2-amino-1-phenyl-1-ethanol, utilisation en therapeutique et procede de preparation
US5101065A (en) * 1991-02-04 1992-03-31 Imperial Chemical Industries Plc Acetophenone intermediates
FR2741067B1 (fr) * 1995-11-10 1997-12-26 Rhone Poulenc Chimie Procede d'acylation d'un thioether aromatique
FR2757160B1 (fr) * 1996-12-13 1999-03-12 Sanofi Sa 1-phenylalkyl-1,2,3,6-tetrahydropyridines
GB201714734D0 (en) * 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) * 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1503517A (fr) * 1965-04-22 1967-12-01 Bayer Ag Procédé de fabrication de d-(-)-n-alcoyl-1-phényl-2-aminoéthanols

Also Published As

Publication number Publication date
JPS541693B1 (US08066781-20111129-C00013.png) 1979-01-27
OA03659A (fr) 1971-12-24
SE384855B (sv) 1976-05-24
AR194457A1 (es) 1973-07-23
FR2070102B1 (US08066781-20111129-C00013.png) 1974-08-23
HU167354B (US08066781-20111129-C00013.png) 1975-09-27
DK147853B (da) 1984-12-24
AT323135B (de) 1975-06-25
IE34545L (en) 1971-04-01
YU238570A (en) 1980-09-25
CS191158B2 (en) 1979-06-29
NO132865B (US08066781-20111129-C00013.png) 1975-10-13
SU578860A3 (ru) 1977-10-30
FR2070102A1 (en) 1971-09-10
NO132865C (US08066781-20111129-C00013.png) 1976-01-21
NL7014444A (US08066781-20111129-C00013.png) 1971-04-05
CA953723A (en) 1974-08-27
IE34545B1 (en) 1975-06-11
FI52714C (fi) 1977-11-10
DK147853C (da) 1986-05-20
FI52714B (US08066781-20111129-C00013.png) 1977-08-01
NL156688B (nl) 1978-05-16
YU35580B (en) 1981-04-30

Similar Documents

Publication Publication Date Title
US3954871A (en) 1-(4-Alkylthiopheny)-2-substituted amino-alcohols and their salts
US4476136A (en) Aminomethyl-5 oxazolidinic derivatives and therapeutic use thereof
JP2637737B2 (ja) 新規な薬剤
EP0373998B1 (fr) Ethers d'oxime de propénone, procédé pour leur préparation et compositions pharmaceutiques les contenant
DK143275B (da) Analogifremgangsmaade til fremstilling af 1-(3-dimethylaminopropyl)-phthalanderivater eller syreadditionssalte deraf
CH542177A (fr) Procédé de préparation d'amino-alcools et de leurs sels
EP0231139B1 (fr) Nouveaux dérivés de dihydrobenzofuranne - et de chromane -carboxamides, leurs procédés de préparation et leur utilisation comme neuroleptiques
CA1306261C (fr) 1,4-dihydropyridines, leur procede de preparation et leur application comme medicaments
PL150477B1 (en) Method of obtaining novel n-/2-(4-fluorophenyl)-1-methyl/-ethyl-n-methyl-n-propynylamine
CH644599A5 (fr) Derives de benzimidazoles, leur preparation ainsi que composition contenant ces derives.
EP0002978B1 (fr) Dérivés de thiazolidinedione-2,4, leur préparation et leur application en thérapeutique
DK174505B1 (da) Benzenderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne
US4474977A (en) Amino-alcohol derivatives
EP0612716B1 (fr) Procédé pour la préparation d'un aminoalcool optiquement pur
CH634311A5 (fr) Derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique.
US3131218A (en) N-amino guanidine derivatives
Neumeyer et al. Pharmacologically active acetylene compounds. II. Propynyl-substituted indole derivatives
US4086357A (en) Amide derivatives
EP0038731B1 (fr) Dérivés de thiazole, leur préparation et leur application en thérapeutique
US5128369A (en) Arylalkylamine derivatives
EP0282390B1 (fr) Nouveaux dérivés de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acétique et les compositions pharmaceutiques qui les contiennent
CH652119A5 (fr) Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication.
EP0275762B1 (fr) Dérivés de l'indole carboxamide ainsi que leurs sels, procédé et intermédiaires de préparation, application à titre de médicaments de ces dérivés et compositions les renfermant
US4727180A (en) Antihypertensive polyhalohydroxylisopropyl phenylalkanoic and phenylalkenoic acids, amides and esters and intermediates thereto
JPS6031829B2 (ja) アミノアルコ−ル誘導体の製造法

Legal Events

Date Code Title Description
PUE Assignment

Owner name: CONTINENTAL PHARMA, INC.

PL Patent ceased