CH523893A - Verfahren zur Herstellung von 2-Thio-pyrimidin-nucleosiden - Google Patents
Verfahren zur Herstellung von 2-Thio-pyrimidin-nucleosidenInfo
- Publication number
- CH523893A CH523893A CH1298869A CH1298869A CH523893A CH 523893 A CH523893 A CH 523893A CH 1298869 A CH1298869 A CH 1298869A CH 1298869 A CH1298869 A CH 1298869A CH 523893 A CH523893 A CH 523893A
- Authority
- CH
- Switzerland
- Prior art keywords
- thio
- preparation
- pyrimidine nucleosides
- nucleosides
- pyrimidine
- Prior art date
Links
- 239000002718 pyrimidine nucleoside Substances 0.000 title 1
- HBCQSNAFLVXVAY-UHFFFAOYSA-N pyrimidine-2-thiol Chemical compound SC1=NC=CC=N1 HBCQSNAFLVXVAY-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0898—Compounds with a Si-S linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681795357 DE1795357A1 (de) | 1968-09-18 | 1968-09-18 | 2-Thio-pyrimidin-nucleoside |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH523893A true CH523893A (de) | 1972-06-15 |
Family
ID=5708152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1298869A CH523893A (de) | 1968-09-18 | 1969-08-27 | Verfahren zur Herstellung von 2-Thio-pyrimidin-nucleosiden |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3708469A (de) |
| JP (1) | JPS5250795B1 (de) |
| AT (1) | AT311560B (de) |
| BE (1) | BE739035A (de) |
| BR (1) | BR6912517D0 (de) |
| CA (1) | CA930732A (de) |
| CH (1) | CH523893A (de) |
| DE (1) | DE1795357A1 (de) |
| DK (1) | DK123823B (de) |
| ES (1) | ES371463A1 (de) |
| FR (1) | FR2018355B1 (de) |
| GB (1) | GB1286854A (de) |
| IE (1) | IE33314B1 (de) |
| NL (1) | NL6914196A (de) |
| PH (1) | PH9966A (de) |
| PL (1) | PL80196B1 (de) |
| RO (1) | RO54466A (de) |
| SE (1) | SE364513B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH541566A (de) * | 1969-04-11 | 1973-09-15 | Schering Ag | Verfahren zur Herstellung von Nucleosiden |
| DE2032424A1 (de) * | 1970-06-23 | 1972-01-20 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 2 Thio 5 aza cytosin und dessen Nucleoside |
| FR2066931A2 (en) * | 1970-10-30 | 1971-08-13 | Schering Ag | 2-thio -6-aza-uridine derivs |
| GB1376437A (en) * | 1970-12-21 | 1974-12-04 | Upjohn Co | Nucleoside derivatives and the preparation thereof |
| US3975374A (en) * | 1970-12-21 | 1976-08-17 | The Upjohn Company | Process for preparing 2-thiouracil nucleosides |
| DE2122991C2 (de) * | 1971-05-04 | 1982-06-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden |
| US4090021A (en) * | 1971-10-08 | 1978-05-16 | Schering Aktiengesellschaft | Process for the production of N6 -substituted adenosine nucleotides and products resulting therefrom |
| US3919193A (en) * | 1973-07-06 | 1975-11-11 | Icn Pharmaceuticals | 3-Deazaguanosine and derivatives thereof |
| US4171431A (en) * | 1976-08-19 | 1979-10-16 | The Upjohn Company | Nucleosides and process |
| DE2721466A1 (de) * | 1977-05-12 | 1978-11-16 | Robugen Gmbh | Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden |
| DE2757365A1 (de) * | 1977-12-20 | 1979-06-21 | Schering Ag | Neues verfahren zur herstellung von nucleosiden |
| US4423212A (en) * | 1980-12-18 | 1983-12-27 | The Upjohn Company | Nucleosides and process |
| US4760137A (en) * | 1984-08-06 | 1988-07-26 | Brigham Young University | Method for the production of 2'-deoxyadenosine compounds |
| CA1269659A (en) * | 1984-08-06 | 1990-05-29 | Brigham Young University | Method for the production of 2'-deoxyadenosine compounds |
-
1968
- 1968-09-18 DE DE19681795357 patent/DE1795357A1/de not_active Withdrawn
-
1969
- 1969-08-19 RO RO60838A patent/RO54466A/ro unknown
- 1969-08-27 CH CH1298869A patent/CH523893A/de not_active IP Right Cessation
- 1969-09-05 GB GB44023/69A patent/GB1286854A/en not_active Expired
- 1969-09-09 IE IE1258/69A patent/IE33314B1/xx unknown
- 1969-09-12 ES ES371463A patent/ES371463A1/es not_active Expired
- 1969-09-15 US US00858163A patent/US3708469A/en not_active Expired - Lifetime
- 1969-09-17 AT AT879769A patent/AT311560B/de not_active IP Right Cessation
- 1969-09-17 SE SE12793/69A patent/SE364513B/xx unknown
- 1969-09-17 DK DK495969AA patent/DK123823B/da unknown
- 1969-09-17 PL PL1969135860A patent/PL80196B1/pl unknown
- 1969-09-18 FR FR696931787A patent/FR2018355B1/fr not_active Expired
- 1969-09-18 BR BR212517/69A patent/BR6912517D0/pt unknown
- 1969-09-18 JP JP44074321A patent/JPS5250795B1/ja active Pending
- 1969-09-18 NL NL6914196A patent/NL6914196A/xx not_active Application Discontinuation
- 1969-09-18 CA CA062386A patent/CA930732A/en not_active Expired
- 1969-09-18 BE BE739035D patent/BE739035A/xx unknown
- 1969-09-18 PH PH10736A patent/PH9966A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5250795B1 (de) | 1977-12-27 |
| PH9966A (en) | 1976-06-16 |
| FR2018355B1 (de) | 1974-02-22 |
| SU399133A3 (de) | 1973-09-27 |
| IE33314L (en) | 1970-03-18 |
| PL80196B1 (de) | 1975-08-30 |
| NL6914196A (de) | 1970-03-20 |
| SE364513B (de) | 1974-02-25 |
| BE739035A (de) | 1970-03-18 |
| BR6912517D0 (pt) | 1973-05-10 |
| CA930732A (en) | 1973-07-24 |
| ES371463A1 (es) | 1971-10-16 |
| RO54466A (de) | 1973-05-17 |
| DE1795357A1 (de) | 1972-01-05 |
| IE33314B1 (en) | 1974-05-15 |
| AT311560B (de) | 1973-11-26 |
| FR2018355A1 (de) | 1970-05-29 |
| DK123823B (da) | 1972-08-07 |
| GB1286854A (en) | 1972-08-23 |
| US3708469A (en) | 1973-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |