CH503692A - Verfahren zur Herstellung eines sekundären Aralkylamins und dessen Salze - Google Patents
Verfahren zur Herstellung eines sekundären Aralkylamins und dessen SalzeInfo
- Publication number
- CH503692A CH503692A CH1410368A CH1410368A CH503692A CH 503692 A CH503692 A CH 503692A CH 1410368 A CH1410368 A CH 1410368A CH 1410368 A CH1410368 A CH 1410368A CH 503692 A CH503692 A CH 503692A
- Authority
- CH
- Switzerland
- Prior art keywords
- filtered
- evapd
- until
- dild
- et2o
- Prior art date
Links
- 150000003974 aralkylamines Chemical class 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- MKKMZZXGIORPMU-UHFFFAOYSA-N 2-(4-phenylmethoxyphenyl)ethanamine Chemical compound C1=CC(CCN)=CC=C1OCC1=CC=CC=C1 MKKMZZXGIORPMU-UHFFFAOYSA-N 0.000 abstract 1
- LSQLSCUJBXFBRB-UHFFFAOYSA-N 2-bromo-1-(4-phenylmethoxyphenyl)propan-1-one Chemical compound C1=CC(C(=O)C(Br)C)=CC=C1OCC1=CC=CC=C1 LSQLSCUJBXFBRB-UHFFFAOYSA-N 0.000 abstract 1
- CLJHABUMMDMAFA-UHFFFAOYSA-N Nylidrin hydrochloride Chemical compound [Cl-].C=1C=C(O)C=CC=1C(O)C(C)[NH2+]C(C)CCC1=CC=CC=C1 CLJHABUMMDMAFA-UHFFFAOYSA-N 0.000 abstract 1
- 230000001813 broncholytic effect Effects 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL6401871A NL6401871A (de) | 1964-02-27 | 1964-02-27 | |
| CH249665A CH472368A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH503692A true CH503692A (de) | 1971-02-28 |
Family
ID=19789406
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH249665A CH472368A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins |
| CH1410468A CH539604A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins und dessen Salze |
| CH1410368A CH503692A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins und dessen Salze |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH249665A CH472368A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins |
| CH1410468A CH539604A (de) | 1964-02-27 | 1965-02-24 | Verfahren zur Herstellung eines sekundären Aralkylamins und dessen Salze |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3410944A (de) |
| AT (4) | AT261590B (de) |
| BE (1) | BE660244A (de) |
| BR (1) | BR6567446D0 (de) |
| CH (3) | CH472368A (de) |
| DE (1) | DE1293782B (de) |
| DK (2) | DK118827B (de) |
| ES (1) | ES309809A1 (de) |
| FR (2) | FR1483718A (de) |
| GB (1) | GB1111451A (de) |
| NL (1) | NL6401871A (de) |
| SE (1) | SE339481B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1962497C3 (de) * | 1969-12-12 | 1979-09-20 | C.H. Boehringer Sohn, 6507 Ingelheim | Naphthylalkyl- a -hydroxyphenäthyl-amine, ihre Herstellung und diese enthaltende Arzneimittel |
| US4704407A (en) * | 1984-12-20 | 1987-11-03 | Eli Lilly And Company | Soluble dobutamine salts |
| MY126489A (en) | 1998-07-08 | 2006-10-31 | Kissei Pharmaceutical | Phenoxyacetic acid derivatives and medicinal compositions containing the same |
| CN102060716A (zh) * | 2009-11-15 | 2011-05-18 | 海南中化联合制药工业股份有限公司 | 一种盐酸利托君的制备方法 |
| IT1399912B1 (it) | 2010-04-29 | 2013-05-09 | Lundbeck Pharmaceuticals Italy S Pa | Processo di preparazione di ritodrina cloridrato. |
| CN102976959B (zh) * | 2012-12-07 | 2014-06-04 | 许学农 | 利托君的制备方法 |
| WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA623286A (en) * | 1961-07-04 | N.V. Philips Gloeilampenfabrieken | Production of optically active 1-(3',4'-dihydroxyphenyl)-2-amino ethanols | |
| NL86359C (de) * | ||||
| US2661373A (en) * | 1953-03-02 | 1953-12-01 | Kulz Ida | Certain amino alcohols and ketones |
| BE612995A (fr) * | 1961-01-23 | 1962-07-23 | Philips Nv | Procédé de préparation d'un nouveau composé à activité optique |
| AT228786B (de) * | 1961-01-23 | 1963-08-12 | Philips Nv | Verfahren zur Herstellung des neuen (-)-Enantiomeren des 1-(p-Hydroxyphenyl)-2-(α-methyl- γ-phenyl-propylamino)-propanols-(1) und seiner Säureadditionssalze |
| US3250803A (en) * | 1961-07-06 | 1966-05-10 | Philips Corp | Method of manufacturing the individual racemates of n-(p-hydroxyphenylisopropyl) arterenol and products |
| NL302260A (de) * | 1963-01-24 | 1900-01-01 |
-
1964
- 1964-02-27 NL NL6401871A patent/NL6401871A/xx unknown
-
1965
- 1965-02-24 SE SE02385/65A patent/SE339481B/xx unknown
- 1965-02-24 CH CH249665A patent/CH472368A/de not_active IP Right Cessation
- 1965-02-24 AT AT161165A patent/AT261590B/de active
- 1965-02-24 AT AT783867A patent/AT268252B/de active
- 1965-02-24 CH CH1410468A patent/CH539604A/de not_active IP Right Cessation
- 1965-02-24 AT AT783767A patent/AT264502B/de active
- 1965-02-24 DK DK95865AA patent/DK118827B/da unknown
- 1965-02-24 CH CH1410368A patent/CH503692A/de not_active IP Right Cessation
- 1965-02-24 DE DEN26270A patent/DE1293782B/de active Pending
- 1965-02-24 AT AT922766A patent/AT270618B/de active
- 1965-02-24 BR BR167446/65A patent/BR6567446D0/pt unknown
- 1965-02-25 GB GB8153/65A patent/GB1111451A/en not_active Expired
- 1965-02-25 ES ES0309809A patent/ES309809A1/es not_active Expired
- 1965-02-25 US US435344A patent/US3410944A/en not_active Expired - Lifetime
- 1965-02-25 BE BE660244A patent/BE660244A/xx unknown
- 1965-02-26 FR FR7240A patent/FR1483718A/fr not_active Expired
- 1965-05-24 FR FR18183A patent/FR4404M/fr not_active Expired
-
1966
- 1966-11-30 DK DK619266AA patent/DK116740B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6567446D0 (pt) | 1973-08-02 |
| AT261590B (de) | 1968-05-10 |
| US3410944A (en) | 1968-11-12 |
| FR1483718A (fr) | 1967-06-09 |
| AT268252B (de) | 1969-02-10 |
| DK118827B (da) | 1970-10-12 |
| AT264502B (de) | 1968-09-10 |
| FR4404M (de) | 1966-10-10 |
| CH539604A (de) | 1973-07-31 |
| GB1111451A (en) | 1968-04-24 |
| BE660244A (de) | 1965-08-25 |
| ES309809A1 (es) | 1965-07-01 |
| CH472368A (de) | 1969-05-15 |
| AT270618B (de) | 1969-05-12 |
| SE339481B (de) | 1971-10-11 |
| DK116740B (da) | 1970-02-09 |
| NL6401871A (de) | 1965-08-30 |
| DE1293782B (de) | 1969-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUE | Assignment |
Owner name: DUPHAR INTERNATIONAL RESEARCH B.V. |
|
| PL | Patent ceased |