CH480315A - Verfahren zur Herstellung von 7-Dihalogenmethyl-3-oxo- 4-steroiden - Google Patents
Verfahren zur Herstellung von 7-Dihalogenmethyl-3-oxo- 4-steroidenInfo
- Publication number
- CH480315A CH480315A CH1299866A CH1299866A CH480315A CH 480315 A CH480315 A CH 480315A CH 1299866 A CH1299866 A CH 1299866A CH 1299866 A CH1299866 A CH 1299866A CH 480315 A CH480315 A CH 480315A
- Authority
- CH
- Switzerland
- Prior art keywords
- dihalomethyl
- steroids
- oxo
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28B—STEAM OR VAPOUR CONDENSERS
- F28B1/00—Condensers in which the steam or vapour is separate from the cooling medium by walls, e.g. surface condenser
- F28B1/06—Condensers in which the steam or vapour is separate from the cooling medium by walls, e.g. surface condenser using air or other gas as the cooling medium
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
- F28F13/00—Arrangements for modifying heat-transfer, e.g. increasing, decreasing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US486226A US3338928A (en) | 1965-09-09 | 1965-09-09 | Fused halocyclopropyl steroids |
| US49909265A | 1965-10-20 | 1965-10-20 | |
| US49909165A | 1965-10-20 | 1965-10-20 | |
| US502375A US3414592A (en) | 1965-09-09 | 1965-10-22 | 6, 7-halomethylene androstanes and estranes and processes for their preparation |
| US502376A US3338893A (en) | 1965-09-09 | 1965-10-22 | Fused halocyclopropyl steroids |
| US513548A US3357973A (en) | 1965-09-09 | 1965-12-13 | 7alpha-mono-and dihalomethyl steroids |
| US581457A US3376292A (en) | 1965-09-09 | 1966-09-23 | 16alpha, 17alpha-dihalomethylene[3, 2-c]pyrazole derivatives of the pregnane series |
| US601862A US3365444A (en) | 1965-09-09 | 1966-12-15 | 5'-hydroxypregneno [3, 2-c] pyrazole derivatives and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH480315A true CH480315A (de) | 1969-10-31 |
Family
ID=27575452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1299866A CH480315A (de) | 1965-09-09 | 1966-09-08 | Verfahren zur Herstellung von 7-Dihalogenmethyl-3-oxo- 4-steroiden |
| CH1299966A CH533094A (de) | 1965-09-09 | 1966-09-08 | Verfahren zur Herstellung neuer Steroide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1299966A CH533094A (de) | 1965-09-09 | 1966-09-08 | Verfahren zur Herstellung neuer Steroide |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US3338928A (de) |
| JP (1) | JPS4812739B1 (de) |
| BE (1) | BE686640A (de) |
| BR (1) | BR6682746D0 (de) |
| CH (2) | CH480315A (de) |
| DE (2) | DE1593426A1 (de) |
| FR (2) | FR1500247A (de) |
| GB (2) | GB1163736A (de) |
| NL (2) | NL6612635A (de) |
| SE (2) | SE348189B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3435057A (en) * | 1966-01-03 | 1969-03-25 | Syntex Corp | 16alpha,17alpha-ethylene and substituted ethylene pregnane derivatives and process |
| US3431256A (en) * | 1966-02-14 | 1969-03-04 | Syntex Corp | 16alpha,17alpha-ethylene and substituted ethylene pregnane derivatives and process |
| US3400137A (en) * | 1966-02-17 | 1968-09-03 | Syntex Corp | 3-desoxy-pregnenes and -19nor-pregnenes and their preparation |
| US3423507A (en) * | 1966-02-25 | 1969-01-21 | Schering Corp | Method of treating benign prostratic hypertrophy |
| CH539621A (de) * | 1966-04-02 | 1973-07-31 | Schering Ag | Verfahren zur Herstellung von 15,16B-Methylensteroiden |
| DE1593501C3 (de) * | 1966-04-02 | 1975-09-11 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 15,16 beta-Methylensteroide der 19-Nor-androstan-Reihe, Verfahren zu deren Herstellung sowie diese enthaltende Mittel |
| US3409610A (en) * | 1966-06-27 | 1968-11-05 | Syntex Corp | 9alpha-difluoromethyl and 9alpha-trifluoromethyl pregnenes |
| US3438975A (en) * | 1966-07-01 | 1969-04-15 | Syntex Corp | 15alpha,16alpha-methylene pregnanes and 19-nor-pregnanes |
| US3541082A (en) * | 1966-09-26 | 1970-11-17 | Upjohn Co | Steroidal delta**16-20(alpha and beta)-hydroperoxide 21-ethers |
| US3444295A (en) * | 1966-12-29 | 1969-05-13 | Schering Ag | Anabolic composition comprising 1,2alpha-methylene-19-nor testosterone |
| DE1643005C3 (de) * | 1967-02-09 | 1975-05-22 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 15,16beta-Methylen-testosterone, Verfahren zu ihrer Herstellung sowie diese Steroide enthaltende Mittel |
| US3435056A (en) * | 1967-09-13 | 1969-03-25 | Syntex Corp | Halogenated cyclopropyl and cyclopropenyl steroids and process for their preparation |
| US3700702A (en) * | 1970-12-02 | 1972-10-24 | Hoffmann La Roche | New 15{62 ,16{62 -methylene steroids |
| GB1377608A (en) * | 1970-12-17 | 1974-12-18 | Glaxo Lab Ltd | 3alpha-hydroxy or acyloxy pregnene-21-ethers |
| US3718673A (en) * | 1971-02-01 | 1973-02-27 | Du Pont | Process for the preparation of 21-chloro-6,6,9alpha-trifluoro-11beta, alpha, 17alpha-trihydroxy-1,4-pregnadien-3,20-dione 16,17-ketals and selected intermediates |
| US3932388A (en) * | 1974-04-22 | 1976-01-13 | Schering Corporation | -Azido-4,6-pregnadieno(3,2-c)pyrazoles, processes for their preparation and intermediates useful therein |
| DE2803187A1 (de) * | 1978-01-23 | 1979-08-02 | Schering Ag | Neue kortikoide, ihre herstellung und verwendung |
| JPS5578308A (en) * | 1978-12-07 | 1980-06-12 | Nippon Denso Co Ltd | Temperature control method |
| IT1149935B (it) * | 1980-07-02 | 1986-12-10 | Finchimica Srl | Uso farmacologico del 6-cloro-17-idrossi 1 alfa,2 alfa-metilpregna 4,6-dien-3,20-dione |
| AU572589B2 (en) | 1983-12-14 | 1988-05-12 | Upjohn Company, The | 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3047566A (en) * | 1958-06-13 | 1962-07-31 | Leo Pharm Prod Ltd | 6a, 6a-dihalo-6, 7-methylene steroids and method |
| US3299054A (en) * | 1961-12-01 | 1967-01-17 | Merck & Co Inc | 4-pregneno-[3, 2-c] pyrazoles and processes of preparing them |
| GB1101119A (en) * | 1964-02-01 | 1968-01-31 | Ormonoterapia Richter Spa | 2ª-aminocarbonyl steroids |
-
1965
- 1965-09-09 US US486226A patent/US3338928A/en not_active Expired - Lifetime
- 1965-10-22 US US502375A patent/US3414592A/en not_active Expired - Lifetime
- 1965-10-22 US US502376A patent/US3338893A/en not_active Expired - Lifetime
- 1965-12-13 US US513548A patent/US3357973A/en not_active Expired - Lifetime
-
1966
- 1966-09-08 DE DE1966S0105745 patent/DE1593426A1/de active Pending
- 1966-09-08 GB GB40196/66A patent/GB1163736A/en not_active Expired
- 1966-09-08 CH CH1299866A patent/CH480315A/de not_active IP Right Cessation
- 1966-09-08 SE SE12107/66A patent/SE348189B/xx unknown
- 1966-09-08 NL NL6612635A patent/NL6612635A/xx unknown
- 1966-09-08 GB GB40197/66A patent/GB1163737A/en not_active Expired
- 1966-09-08 NL NL6612687A patent/NL6612687A/xx unknown
- 1966-09-08 BE BE686640A patent/BE686640A/xx unknown
- 1966-09-08 CH CH1299966A patent/CH533094A/de not_active IP Right Cessation
- 1966-09-08 SE SE7202447*3A patent/SE376426B/xx unknown
- 1966-09-08 DE DE1966S0105746 patent/DE1593427A1/de active Pending
- 1966-09-09 BR BR182746/66A patent/BR6682746D0/pt unknown
- 1966-09-09 FR FR75856A patent/FR1500247A/fr not_active Expired
- 1966-09-23 US US581457A patent/US3376292A/en not_active Expired - Lifetime
- 1966-12-09 FR FR86923A patent/FR6651M/fr not_active Expired
- 1966-12-15 US US601862A patent/US3365444A/en not_active Expired - Lifetime
-
1971
- 1971-03-25 JP JP46017563A patent/JPS4812739B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4812739B1 (de) | 1973-04-23 |
| GB1163736A (en) | 1969-09-10 |
| US3357973A (en) | 1967-12-12 |
| DE1593427A1 (de) | 1970-07-30 |
| US3338893A (en) | 1967-08-29 |
| NL6612687A (de) | 1967-03-10 |
| NL6612635A (de) | 1967-03-10 |
| BR6682746D0 (pt) | 1973-12-26 |
| CH533094A (de) | 1973-01-31 |
| FR1500247A (fr) | 1967-11-03 |
| BE686640A (de) | 1967-02-15 |
| US3365444A (en) | 1968-01-23 |
| US3376292A (en) | 1968-04-02 |
| GB1163737A (en) | 1969-09-10 |
| FR6651M (de) | 1969-01-27 |
| DE1593426A1 (de) | 1970-07-30 |
| SE376426B (de) | 1975-05-26 |
| US3414592A (en) | 1968-12-03 |
| SE348189B (de) | 1972-08-28 |
| US3338928A (en) | 1967-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |