CH461517A - Verfahren zur Herstellung von Benzodiazepin-Derivaten - Google Patents

Verfahren zur Herstellung von Benzodiazepin-Derivaten

Info

Publication number
CH461517A
CH461517A CH20067A CH20067A CH461517A CH 461517 A CH461517 A CH 461517A CH 20067 A CH20067 A CH 20067A CH 20067 A CH20067 A CH 20067A CH 461517 A CH461517 A CH 461517A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH20067A
Other languages
English (en)
Inventor
Allan Archer Giles
Henryk Sternbach Leo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1145468A priority Critical patent/CH509977A/de
Priority to CH1145368A priority patent/CH471092A/de
Priority to CH1145568A priority patent/CH471825A/de
Publication of CH461517A publication Critical patent/CH461517A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C07D239/76N-oxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
CH20067A 1966-01-19 1967-01-06 Verfahren zur Herstellung von Benzodiazepin-Derivaten CH461517A (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CH1145468A CH509977A (de) 1966-01-19 1967-01-06 Verfahren zur Herstellung von neuen Oximen
CH1145368A CH471092A (de) 1966-01-19 1967-01-06 Verfahren zur Herstellung von neuen Oximen
CH1145568A CH471825A (de) 1966-01-19 1967-01-06 Verfahren zur Herstellung von neuen Oximen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52155166A 1966-01-19 1966-01-19

Publications (1)

Publication Number Publication Date
CH461517A true CH461517A (de) 1968-08-31

Family

ID=24077176

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1862266A CH553193A (en) 1966-01-19 1966-12-27 Prepn of 1 4-benzodiazepine 4-oxides from novel oximes
CH438369A CH560692A5 (de) 1966-01-19 1966-12-27
CH20067A CH461517A (de) 1966-01-19 1967-01-06 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH1862266A CH553193A (en) 1966-01-19 1966-12-27 Prepn of 1 4-benzodiazepine 4-oxides from novel oximes
CH438369A CH560692A5 (de) 1966-01-19 1966-12-27

Country Status (16)

Country Link
US (1) US3446806A (de)
JP (1) JPS4938814B1 (de)
BE (2) BE692378A (de)
CH (3) CH553193A (de)
DE (2) DE1695176A1 (de)
DK (4) DK114556B (de)
ES (2) ES335789A1 (de)
FI (1) FI47576C (de)
FR (2) FR1507878A (de)
GB (2) GB1144516A (de)
GR (2) GR35752B (de)
IL (2) IL27189A (de)
MY (2) MY6900383A (de)
NL (3) NL6700785A (de)
OA (1) OA02391A (de)
SE (4) SE335858B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310429A (en) * 1978-06-19 1982-01-12 The B. F. Goodrich Company Stabilized polymers, novel stabilizers, and synthesis thereof
US4601839A (en) * 1978-06-19 1986-07-22 The B. F. Goodrich Company Stabilized polymers, novel stabilizers, and synthesis thereof
US4472435A (en) * 1980-07-31 1984-09-18 Hoffman-La Roche Inc. Benzophenone derivatives useful in treating heart failure
WO1995024394A1 (en) * 1994-03-08 1995-09-14 Takeda Chemical Industries, Ltd. Quinoline or quinazoline derivatives as anti-inflammatory agents, in particular for treating arthritis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3267110A (en) * 1960-06-03 1966-08-16 Smith Kline French Lab Trifluoromethyl substituted o-aminophenyl ketones
US3321467A (en) * 1963-11-27 1967-05-23 Hoffmann La Roche 3-halo-1, 4-benzodiazepin-2-ones

Also Published As

Publication number Publication date
NL6700786A (de) 1967-07-20
IL27212A (en) 1971-04-28
OA02391A (fr) 1970-05-05
DK114556B (da) 1969-07-14
GR33806B (el) 1968-02-06
JPS4938814B1 (de) 1974-10-21
FR1508490A (fr) 1968-01-05
SE335858B (de) 1971-06-14
BE692558A (de) 1967-07-13
CH553193A (en) 1974-08-30
IL27189A (en) 1971-01-28
FI47576B (de) 1973-10-01
GB1144515A (en) 1969-03-05
SE321233B (de) 1970-03-02
ES335789A1 (es) 1967-12-16
US3446806A (en) 1969-05-27
DE1695176A1 (de) 1970-04-16
GR35752B (el) 1968-10-25
DE1618486A1 (de) 1971-04-01
MY6900384A (en) 1969-12-31
DK119656B (da) 1971-02-08
SE353717B (de) 1973-02-12
MY6900383A (en) 1969-12-31
DK120392B (da) 1971-05-24
CH560692A5 (de) 1975-04-15
NL6700785A (de) 1967-07-20
SE386168B (sv) 1976-08-02
NL131198C (de)
ES335788A1 (es) 1968-03-16
DK120347B (da) 1971-05-17
FI47576C (fi) 1974-01-10
FR1507878A (fr) 1967-12-29
GB1144516A (en) 1969-03-05
BE692378A (de) 1967-07-10

Similar Documents

Publication Publication Date Title
CH492676A (de) Verfahren zur Herstellung von 1-Phenyl-2-aminoäthanol-Derivaten
CH460793A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH491119A (de) Verfahren zur Herstellung von N6-Aralkyl-adenosin-derivaten
CH489517A (de) Verfahren zur Herstellung von N-Acylsydnoniminderivaten
CH462831A (de) Verfahren zur Herstellung von Benzodiazepinderivaten
CH475193A (de) Verfahren zur Herstellung von Phenylalaninderivaten
CH526558A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
AT268285B (de) Verfahren zur Herstellung von Benzodiazepinderivaten
CH473133A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH498846A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH510640A (de) Verfahren zur Herstellung von Diarylcyclopropan-Derivaten
CH524620A (de) Verfahren zur Herstellung von Benzodiazepinderivaten
CH511864A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH478812A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
AT280295B (de) Verfahren zur Herstellung von Benzodiazepinderivaten
CH461517A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH460791A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH490401A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH524561A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH493539A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH496663A (de) Verfahren zur Herstellung von 2-Benzyliden-cyclopentanonderivaten
CH491938A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH484163A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH484164A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH482692A (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten