CH438344A - Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen - Google Patents

Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen

Info

Publication number
CH438344A
CH438344A CH247764A CH247764A CH438344A CH 438344 A CH438344 A CH 438344A CH 247764 A CH247764 A CH 247764A CH 247764 A CH247764 A CH 247764A CH 438344 A CH438344 A CH 438344A
Authority
CH
Switzerland
Prior art keywords
pyrimidines
preparation
basic substituted
substituted pyrimido
pyrimido
Prior art date
Application number
CH247764A
Other languages
German (de)
English (en)
Inventor
Scheffler Heinz
Josef Dr Roch
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH438344A publication Critical patent/CH438344A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH247764A 1963-03-09 1964-02-28 Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen CH438344A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DET0023605 1963-03-09

Publications (1)

Publication Number Publication Date
CH438344A true CH438344A (de) 1967-06-30

Family

ID=7551073

Family Applications (1)

Application Number Title Priority Date Filing Date
CH247764A CH438344A (de) 1963-03-09 1964-02-28 Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen

Country Status (5)

Country Link
CH (1) CH438344A (https=)
DE (1) DE1470341C3 (https=)
FR (1) FR3713M (https=)
GB (1) GB1051218A (https=)
IT (1) IT7950418A0 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081471A1 (https=) * 1970-01-30 1971-12-03 Thomae Gmbh Dr K

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049207A1 (de) * 1980-12-27 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neue trisubstituierte pyrimido (5,4-d) pyrimidine, ihre herstellung und ihre verwendung als arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006524203A (ja) 2003-04-24 2006-10-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング トロンビンの過剰形成及び／又はトロンビンレセプターの発現上昇により生じる血栓塞栓性疾病及び疾患の治療及び予防のためのジピリダモール又はモピダモールの使用
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
DK2681236T3 (en) 2011-03-01 2018-04-16 Synergy Pharmaceuticals Inc PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
WO2014131024A2 (en) 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP4706758A3 (en) 2019-05-21 2026-05-06 Ardelyx, Inc. Methods for inhibiting phosphate transport
TW202309022A (zh) 2021-04-13 2023-03-01 美商努法倫特公司 用於治療具egfr突變之癌症之胺基取代雜環

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081471A1 (https=) * 1970-01-30 1971-12-03 Thomae Gmbh Dr K

Also Published As

Publication number Publication date
IT7950418A0 (it) 1979-10-01
GB1051218A (https=)
FR3713M (fr) 1965-11-29
DE1470341C3 (de) 1974-07-04
DE1470341B2 (de) 1973-12-06
DE1470341A1 (de) 1969-07-03

Similar Documents

Publication Publication Date Title
CH446361A (de) Verfahren zur Herstellung von neuen Thieno(3,2-d)pyrimidinen
CH467270A (de) Verfahren zur Herstellung von Pyrimidinverbindungen
CH437327A (de) Verfahren zur Herstellung von neuen 5,6,7,8-Tetrahydropyrido (4,3-d) pyrimidinen
CH438344A (de) Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen
CH456608A (de) Verfahren zur Herstellung von Pyrimidinderivaten
CH481924A (de) Verfahren zur Herstellung von 6-Aminophenyl- und 6-Acylaminophenyl-4,5-dihydropyridazonen (3)
CH522666A (de) Verfahren zur Herstellung von s-Triazolo-(1,5-a)-pyrimidinen
CH382178A (de) Verfahren zur Herstellung von substituierten 2,4-Diamino-7-oxy-pyrido (2,3-d) pyrimidinen
CH443322A (de) Verfahren zur Herstellung von s-Triazinen
CH507266A (de) Verfahren zur Herstellung von Pyrazolo(3,4-d)pyrimidinen
CH489511A (de) Verfahren zur Herstellung von substituierten s-Triazinen
CH435305A (de) Verfahren zur Herstellung von neuen 5,6,7,8-Tetrahydropyrido (4,3-d)pyrimidinen
CH446358A (de) Verfahren zur Herstellung von neuen Dihydrothieno(3,2-d)pyrimidinen
CH446357A (de) Verfahren zur Herstellung von substituierten 1,4 Benzodiazepinverbindungen
CH481935A (de) Verfahren zur Herstellung von N-Acyl-3,4-dihydrooxazinen-(1,3)
CH431551A (de) Verfahren zur Herstellung von v-Triazino (5,4-d) pyrimidinen
CH414657A (de) Verfahren zur Herstellung von 2,4-Diamino-pyrido(2,3-d)pyrimidinen
CH469737A (de) Verfahren zur Herstellung von neuen 4H-m-Dithiino(5,4-d)pyrimidinen
CH457474A (de) Verfahren zur Herstellung von 2,4-Diamino-7-chlorpyrido(2,3-d)pyrimidinen
CH484929A (de) Verfahren zur Herstellung von Pyrazolo (3,4-d)pyrimidinen
CH529143A (de) Verfahren zur Herstellung von neuen 2,6-Bis(dialkanol-amino)-pyrimido(5,4-d)pyrimidinen
CH430739A (de) Verfahren zur Herstellung von in 5-Stellung substituierten 5,6-Dihydro-6-oxo-11H-pyrido(2,3-b)(1,4) benzodiazepinen
CH477451A (de) Verfahren zur Herstellung von 2-Methoxy-4-(N4-glutarylsulfanilamido)chinazolin
CH505134A (de) Verfahren zur Herstellung von 2 Oxo-(2 Thiono)-4-thionodihydrobenzoaxinen-(1,3)
AT266800B (de) Verfahren zur Herstellung von 2-Thiapropandiol-(1,3)