CH420132A - Verfahren zur Herstellung von 17a-Haloäthinylsteroiden der Androstan- oder 19-Nor-androstanreihe - Google Patents

Verfahren zur Herstellung von 17a-Haloäthinylsteroiden der Androstan- oder 19-Nor-androstanreihe

Info

Publication number
CH420132A
CH420132A CH466861A CH466861A CH420132A CH 420132 A CH420132 A CH 420132A CH 466861 A CH466861 A CH 466861A CH 466861 A CH466861 A CH 466861A CH 420132 A CH420132 A CH 420132A
Authority
CH
Switzerland
Prior art keywords
androstane
haloethinyl
steroids
preparation
series
Prior art date
Application number
CH466861A
Other languages
German (de)
English (en)
Inventor
Eugene Oberster Arthur
Eldon Beyler Roger
Hastings Sarett Lewis
Seth Bry Thomas
Fried John
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US23396A external-priority patent/US3211725A/en
Priority claimed from US23394A external-priority patent/US3121079A/en
Priority claimed from US23393A external-priority patent/US3100204A/en
Priority claimed from US23397A external-priority patent/US3067214A/en
Priority claimed from US23392A external-priority patent/US3246021A/en
Priority claimed from US88575A external-priority patent/US3072646A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH420132A publication Critical patent/CH420132A/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH466861A 1960-04-20 1961-04-20 Verfahren zur Herstellung von 17a-Haloäthinylsteroiden der Androstan- oder 19-Nor-androstanreihe CH420132A (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US2339560A 1960-04-20 1960-04-20
US23396A US3211725A (en) 1960-04-20 1960-04-20 6alpha-methyl-21 halo nor ethisterones and intermediates in the preparation thereof
US23394A US3121079A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23393A US3100204A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23397A US3067214A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23392A US3246021A (en) 1960-04-20 1960-04-20 Intermediates in the preparation of 6beta-methyl-halo ethisterone compounds
US5947960A 1960-09-30 1960-09-30
US8857461A 1961-03-02 1961-03-02
US88575A US3072646A (en) 1961-03-02 1961-03-02 Novel 6-chloro-17alpha-haloethynyl-19-norandrostadienes and processes

Publications (1)

Publication Number Publication Date
CH420132A true CH420132A (de) 1966-09-15

Family

ID=27578025

Family Applications (2)

Application Number Title Priority Date Filing Date
CH466861A CH420132A (de) 1960-04-20 1961-04-20 Verfahren zur Herstellung von 17a-Haloäthinylsteroiden der Androstan- oder 19-Nor-androstanreihe
CH1181965A CH433280A (de) 1960-04-20 1961-04-20 Verfahren zur Herstellung von 17a-Haloäthinylsteroiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1181965A CH433280A (de) 1960-04-20 1961-04-20 Verfahren zur Herstellung von 17a-Haloäthinylsteroiden

Country Status (4)

Country Link
BE (1) BE602768A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH420132A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB990359A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (2) SE313052B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19800468A1 (de) * 1998-01-09 1999-07-15 Niederhoff & Sieper Gmbh Schloß mit Falle
CN101298465B (zh) * 2008-06-26 2011-02-16 湖北葛店人福药业有限责任公司 一种环丙孕酮醋酸酯的合成方法

Also Published As

Publication number Publication date
SE313052B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-08-04
CH433280A (de) 1967-04-15
BE602768A (fr) 1961-10-19
GB990359A (en) 1965-04-28
SE313053B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-08-04

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