CH420132A - Process for the preparation of 17a-haloethinyl steroids of the androstane or 19-nor-androstane series - Google Patents

Process for the preparation of 17a-haloethinyl steroids of the androstane or 19-nor-androstane series

Info

Publication number
CH420132A
CH420132A CH466861A CH466861A CH420132A CH 420132 A CH420132 A CH 420132A CH 466861 A CH466861 A CH 466861A CH 466861 A CH466861 A CH 466861A CH 420132 A CH420132 A CH 420132A
Authority
CH
Switzerland
Prior art keywords
androstane
haloethinyl
steroids
preparation
series
Prior art date
Application number
CH466861A
Other languages
German (de)
Inventor
Eugene Oberster Arthur
Eldon Beyler Roger
Hastings Sarett Lewis
Seth Bry Thomas
Fried John
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US23394A external-priority patent/US3121079A/en
Priority claimed from US23396A external-priority patent/US3211725A/en
Priority claimed from US23393A external-priority patent/US3100204A/en
Priority claimed from US23397A external-priority patent/US3067214A/en
Priority claimed from US23392A external-priority patent/US3246021A/en
Priority claimed from US88575A external-priority patent/US3072646A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH420132A publication Critical patent/CH420132A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH466861A 1960-04-20 1961-04-20 Process for the preparation of 17a-haloethinyl steroids of the androstane or 19-nor-androstane series CH420132A (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US2339560A 1960-04-20 1960-04-20
US23394A US3121079A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23396A US3211725A (en) 1960-04-20 1960-04-20 6alpha-methyl-21 halo nor ethisterones and intermediates in the preparation thereof
US23393A US3100204A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23397A US3067214A (en) 1960-04-20 1960-04-20 Haloethisterone compounds
US23392A US3246021A (en) 1960-04-20 1960-04-20 Intermediates in the preparation of 6beta-methyl-halo ethisterone compounds
US5947960A 1960-09-30 1960-09-30
US8857461A 1961-03-02 1961-03-02
US88575A US3072646A (en) 1961-03-02 1961-03-02 Novel 6-chloro-17alpha-haloethynyl-19-norandrostadienes and processes

Publications (1)

Publication Number Publication Date
CH420132A true CH420132A (en) 1966-09-15

Family

ID=27578025

Family Applications (2)

Application Number Title Priority Date Filing Date
CH466861A CH420132A (en) 1960-04-20 1961-04-20 Process for the preparation of 17a-haloethinyl steroids of the androstane or 19-nor-androstane series
CH1181965A CH433280A (en) 1960-04-20 1961-04-20 Process for the preparation of 17a-haloethinyl steroids

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1181965A CH433280A (en) 1960-04-20 1961-04-20 Process for the preparation of 17a-haloethinyl steroids

Country Status (4)

Country Link
BE (1) BE602768A (en)
CH (2) CH420132A (en)
GB (1) GB990359A (en)
SE (2) SE313052B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19800468A1 (en) * 1998-01-09 1999-07-15 Niederhoff & Sieper Gmbh Lock with trap
CN101298465B (en) * 2008-06-26 2011-02-16 湖北葛店人福药业有限责任公司 Improved synthetic method of cyproterone acetate

Also Published As

Publication number Publication date
SE313053B (en) 1969-08-04
GB990359A (en) 1965-04-28
SE313052B (en) 1969-08-04
CH433280A (en) 1967-04-15
BE602768A (en) 1961-10-19

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