CH383984A - Process for the preparation of a therapeutically useful product - Google Patents
Process for the preparation of a therapeutically useful productInfo
- Publication number
- CH383984A CH383984A CH1115860A CH1115860A CH383984A CH 383984 A CH383984 A CH 383984A CH 1115860 A CH1115860 A CH 1115860A CH 1115860 A CH1115860 A CH 1115860A CH 383984 A CH383984 A CH 383984A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- therapeutically useful
- useful product
- choline
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Verfahren zur Herstellung eines therapeutisch verwendbaren Produktes Gegenstand der vorliegenden Erfindung ist ein. Verfahren zur Herstellung eines therapeutisch ver wendbaren Produktes, welches dadurch gekennzeich- net ist, dass Uracil-4-carbonsäure (2,6-Dioxy-pyrimi- din-4-carbonsäure) mit Cholin zum uracilcarbon- sauren Cholin vereinigt wird.
<I>Beispiel</I> Cholinchlorid, gelöst in Wasser, wird mittels eines geeigneten Anionenaustauschers in die freie Base übergeführt und hierauf mit der äquivalenten Menge Uracilcarbonsäure das Salz gebildet. Das erhaltene uracilcarbonsaure Cholin ist ein weisses, körniges, vollständig in Wasser lösliches Produkt mit einem Cholingehalt (als Cholin-Reineckat bestimmt), der praktisch dem theoretischen Wert entspricht.
Das Salz hat die Formel:
EMI0001.0025
Process for the preparation of a therapeutically useful product The present invention is a. Process for the production of a therapeutically usable product, which is characterized in that uracil-4-carboxylic acid (2,6-dioxy-pyrimidine-4-carboxylic acid) is combined with choline to form uracil-carboxylic acid choline.
<I> Example </I> Choline chloride, dissolved in water, is converted into the free base using a suitable anion exchanger and the salt is then formed with the equivalent amount of uracilic acid. The uracilcarboxylic acid choline obtained is a white, granular, completely water-soluble product with a choline content (determined as pure choline) that practically corresponds to the theoretical value.
The salt has the formula:
EMI0001.0025
Claims (1)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1115860A CH383984A (en) | 1960-10-05 | 1960-10-05 | Process for the preparation of a therapeutically useful product |
| FR875008A FR1386M (en) | 1960-10-05 | 1961-10-04 | New derivative of choline and its use in therapy, in particular as a lipotropic agent. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1115860A CH383984A (en) | 1960-10-05 | 1960-10-05 | Process for the preparation of a therapeutically useful product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH383984A true CH383984A (en) | 1964-11-15 |
Family
ID=4370651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1115860A CH383984A (en) | 1960-10-05 | 1960-10-05 | Process for the preparation of a therapeutically useful product |
Country Status (2)
| Country | Link |
|---|---|
| CH (1) | CH383984A (en) |
| FR (1) | FR1386M (en) |
-
1960
- 1960-10-05 CH CH1115860A patent/CH383984A/en unknown
-
1961
- 1961-10-04 FR FR875008A patent/FR1386M/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1386M (en) | 1962-07-02 |
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