CH306916A - Process for the preparation of a diammonium compound. - Google Patents

Process for the preparation of a diammonium compound.

Info

Publication number
CH306916A
CH306916A CH306916DA CH306916A CH 306916 A CH306916 A CH 306916A CH 306916D A CH306916D A CH 306916DA CH 306916 A CH306916 A CH 306916A
Authority
CH
Switzerland
Prior art keywords
preparation
diammonium compound
bis
diammonium
compound
Prior art date
Application number
Other languages
German (de)
Inventor
Ag J R Geigy
Original Assignee
Ag J R Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ag J R Geigy filed Critical Ag J R Geigy
Publication of CH306916A publication Critical patent/CH306916A/en

Links

Landscapes

  • Hydrogenated Pyridines (AREA)

Description

  

  Verfahren zur     Herstellung        einer        Diammoniumverhindung.       Gegenstand vorliegenden Patentes ist ein  Verfahren zur Herstellung einer     Diammo-          niumverbindung.    Das Verfahren ist dadurch  gekennzeichnet, dass man auf 1     Mol        1,10-Bis-          (ss-piperidino-äthoxy)-dekan    2     Mol        Bromessig-          säure-n-propylester    einwirken lässt.  



  Die erhaltene neue Verbindung, das     1,10-          Bis        [ss-(-carbohexyloxymethyl-morpholinium)-          äthoxy]-dekan-dibromid,    schmilzt bei 152 . Sie  soll als Arzneimittel und als Zwischenprodukt  für Arzneimittel Verwendung finden.  



  <I>Beispiel:</I>  3,96 Teile     1,10-Bis-(ss-piperidino-äthoxy)-          dekan,    20     Volumteile    Aceton und 4,3 Teile       Bromessigsäure-n-propylesterwerden    etwa 14  Stunden unter     Rückfluss    gekocht.

   Das     quar-          tHre    Salz wird nach Erkalten, falls ölig ab-    geschieden, zuerst durch Kühlen und Reiben  zur     Kristallisation    gebracht,     abgesaugt,        ge-          wünsehtenfalls        aus;    heissem     Butanon,    unter  Zusatz von     Propanol    umkristallisiert und im  Vakuum bei 50-60  getrocknet. Es schmilzt  bei 152 .



  Process for the preparation of a diammonium compound. The present patent relates to a process for the preparation of a diammonium compound. The process is characterized in that 1 mole of 1,10-bis (ss-piperidino-ethoxy) decane is allowed to act with 2 moles of n-propyl bromoacetate.



  The new compound obtained, the 1,10-bis [ss - (- carbohexyloxymethyl-morpholinium) -ethoxy] -dekan-dibromide, melts at 152. It should be used as a medicinal product and as an intermediate product for medicinal products.



  <I> Example: </I> 3.96 parts of 1,10-bis (ss-piperidino-ethoxy) -decane, 20 parts by volume of acetone and 4.3 parts of n-propyl bromoacetate are refluxed for about 14 hours.

   After cooling, the quaternary salt, if deposited oily, is first made to crystallize by cooling and rubbing, then sucked off, if necessary removed; hot butanone, recrystallized with the addition of propanol and dried in vacuo at 50-60. It melts at 152.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer Diammo- niumverbindimg, dadurch gekennzeichnet, dass man auf 1 Mol 1,10-Bis-(ss-piperidino-äthoxy)- dekan 2 Mol Bromessigsäure-n-propylester ein wirken lässt. Die erhaltene neue Verbindung, das 1,10- Bis- [ss- (carbo-n-propoxymethyl-piper idinium)- ä.thoxy]-dekan-dibromid, schmilzt bei 152 . PATENT CLAIM: A process for the production of a diammonium compound, characterized in that 2 moles of n-propyl bromoacetate are allowed to act on 1 mole of 1,10-bis- (ss-piperidino-ethoxy) decane. The new compound obtained, the 1,10-bis- [ss- (carbo-n-propoxymethyl-piperidinium) -ä.thoxy] -dekan-dibromid, melts at 152.
CH306916D 1952-04-22 1952-04-22 Process for the preparation of a diammonium compound. CH306916A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH306916T 1952-04-22
CH305263T 1952-04-22

Publications (1)

Publication Number Publication Date
CH306916A true CH306916A (en) 1955-04-30

Family

ID=25734929

Family Applications (1)

Application Number Title Priority Date Filing Date
CH306916D CH306916A (en) 1952-04-22 1952-04-22 Process for the preparation of a diammonium compound.

Country Status (1)

Country Link
CH (1) CH306916A (en)

Similar Documents

Publication Publication Date Title
CH306916A (en) Process for the preparation of a diammonium compound.
CH306913A (en) Process for the preparation of a diammonium compound.
CH307551A (en) Process for the preparation of a diammonium compound.
CH306912A (en) Process for the preparation of a diammonium compound.
CH306914A (en) Process for the preparation of a diammonium compound.
CH306923A (en) Process for the preparation of a diammonium compound.
CH306917A (en) Process for the preparation of a diammonium compound.
CH306911A (en) Process for the preparation of a diammonium compound.
CH306920A (en) Process for the preparation of a diammonium compound.
CH306908A (en) Process for the preparation of a diammonium compound.
CH307558A (en) Process for the preparation of a diammonium compound.
CH306915A (en) Process for the preparation of a diammonium compound.
CH307556A (en) Process for the preparation of a diammonium compound.
CH306918A (en) Process for the preparation of a diammonium compound.
CH307562A (en) Process for the preparation of a diammonium compound.
CH306924A (en) Process for the preparation of a diammonium compound.
CH306922A (en) Process for the preparation of a diammonium compound.
CH306910A (en) Process for the preparation of a diammonium compound.
CH307564A (en) Process for the preparation of a diammonium compound.
CH306921A (en) Process for the preparation of a diammonium compound.
CH306919A (en) Process for the preparation of a diammonium compound.
CH306909A (en) Process for the preparation of a diammonium compound.
CH307555A (en) Process for the preparation of a diammonium compound.
CH307559A (en) Process for the preparation of a diammonium compound.
CH307561A (en) Process for the preparation of a diammonium compound.