CH300446A - Process for the preparation of an aryl-substituted pyrazoline compound. - Google Patents

Process for the preparation of an aryl-substituted pyrazoline compound.

Info

Publication number
CH300446A
CH300446A CH300446DA CH300446A CH 300446 A CH300446 A CH 300446A CH 300446D A CH300446D A CH 300446DA CH 300446 A CH300446 A CH 300446A
Authority
CH
Switzerland
Prior art keywords
aryl
preparation
substituted pyrazoline
compound
pyrazoline compound
Prior art date
Application number
Other languages
German (de)
Inventor
Limited Ilford
Original Assignee
Ilford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ilford Ltd filed Critical Ilford Ltd
Publication of CH300446A publication Critical patent/CH300446A/en

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

      Verfahren        zur    Herstellung einer     arylsubstituierten        Pyrazolinverbindung.       Im Hauptpatent ist ein Verfahren zur Her  stellung einer     arylsubstituierten        Pyrazolin-          verbindung    beschrieben, welches dadurch ge  kennzeichnet     ist,    dass man eine den Rest  
EMI0001.0009     
    abgebende Verbindung mit     Phenylhydrazin-          p-sulfonsäilre    kondensiert.

   Als zur Abgabe  dieses Restes geeignete Verbindungen     werden          Benzal.acetophenon    und seine     Dialkylamino-          Additionsverbindungen    genannt.  



  Gegenstand     des    vorliegenden Patentes     ist     gleichfalls ein Verfahren zur     Herstellung     einer     arylsubstituierten        Pyrazolinverbindl-mg,     bei welchem aber     eine    den Rest  
EMI0001.0022     
    abgebende Verbindung mit     p-Sulfophenyl-          hydrazin    kondensiert wird.  



  <I>Beispiel:</I>  100 Teile     p-Aeetamino-ss-dimethylamino-          propiophenon-hydrochlorid,    hergestellt aus     p-          Acetaminoacetophenon,    Formaldehyd und         Dimethylamin,

          und    78 Teile des     Kaliumsalzes     von     p-Sulfophenylhydrazin    werden in 400       Volumteilen        10        %        iger        wässriger        Kaliumearbo-          natlösimg    gelöst und die Lösung während 3       Sti-mden    gekocht. Beim Abkühlen kristallisiert  das     Kaliiunsalz    des     1-(p-Sulfophenyl)-3-(p-          acetaminophenyl)-pyrazolins    aus.

   Durch An  säuern einer Lösung des Salzes mit Salzsäure  wird die freie Säure in Form     blassgelber    Kri  stalle erhalten.   Die neue     Verbindung,    das     1-(p-Sulfo-          phenyl)-3-(p-acetaminophenyl)-pyrazolin,    soll  als     Aufhellungsmittel    benutzt werden.



      Process for the preparation of an aryl-substituted pyrazoline compound. In the main patent, a method for preparing an aryl-substituted pyrazoline compound is described, which is characterized in that one is the rest
EMI0001.0009
    donating compound condensed with phenylhydrazine-p-sulfonic acid.

   Benzal.acetophenon and its dialkylamino addition compounds are mentioned as compounds suitable for releasing this residue.



  The subject of the present patent is also a process for the preparation of an aryl-substituted Pyrazolinverbindl-mg, in which, however, the remainder
EMI0001.0022
    The donating compound is condensed with p-sulfophenylhydrazine.



  <I> Example: </I> 100 parts of p-acetamino-ss-dimethylamino-propiophenone hydrochloride, made from p-acetaminoacetophenone, formaldehyde and dimethylamine

          and 78 parts of the potassium salt of p-sulfophenylhydrazine are dissolved in 400 parts by volume of 10% aqueous potassium carbonate solution and the solution is boiled for 3 hours. On cooling, the potassium salt of 1- (p-sulfophenyl) -3- (p-acetaminophenyl) pyrazoline crystallizes out.

   By acidifying a solution of the salt with hydrochloric acid, the free acid is obtained in the form of pale yellow crystals. The new compound, 1- (p-sulfophenyl) -3- (p-acetaminophenyl) pyrazoline, is said to be used as a lightening agent.

Claims (1)

PATENTANSPRUCH Verfahren zur Herstellung einer arylsub- stituierten Pyrazolinv erbindung, dadurch ge kennzeichnet, dass man eine den Rest EMI0001.0055 abgebende Verbindung mit Phenylhydrazin-p- sulfonsäure kondensiert. Die neue Verbindung, das 1-(p-Sulfo- phenyl)-3-(p-acetaminophenyl)-pyrazolin, wird in Form blassgelber Kristalle erhalten. PATENT CLAIM Process for the production of an aryl-substituted pyrazoline compound, characterized in that one the remainder EMI0001.0055 donating compound condensed with phenylhydrazine-p-sulfonic acid. The new compound, 1- (p-sulfophenyl) -3- (p-acetaminophenyl) pyrazoline, is obtained in the form of pale yellow crystals.
CH300446D 1950-06-03 1950-06-03 Process for the preparation of an aryl-substituted pyrazoline compound. CH300446A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH293111T 1950-06-03
CH300446T 1950-06-03

Publications (1)

Publication Number Publication Date
CH300446A true CH300446A (en) 1954-07-31

Family

ID=25733326

Family Applications (1)

Application Number Title Priority Date Filing Date
CH300446D CH300446A (en) 1950-06-03 1950-06-03 Process for the preparation of an aryl-substituted pyrazoline compound.

Country Status (1)

Country Link
CH (1) CH300446A (en)

Similar Documents

Publication Publication Date Title
CH300446A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300440A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300443A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300441A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300445A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300447A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300444A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300442A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300439A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
CH300448A (en) Process for the preparation of an aryl-substituted pyrazoline compound.
DE747119C (en) Process for the preparation of a sulfanilamide compound which is free of impurities and is particularly suitable for external use
DE858697C (en) Process for the preparation of Dicarbonsaeuredimethylolamiden
CH189749A (en) Method for the preparation of 17-methyl-dihydrofollicle hormone.
CH250003A (en) Process for the preparation of a benzenesulfonamide derivative.
DE651322C (en) Process for the preparation of durable solutions of glyceric calcium
AT67948B (en) Process for the preparation of homologues and substitution products of 2-piperonylquinoline-4-carboxylic acid.
CH218517A (en) Process for the preparation of 1-methyl-4-phenyl-piperidyl-4-isopropyl-ketone.
CH295836A (en) Process for the preparation of a product of the thiosemicarbazone series.
CH211427A (en) Process for the preparation of an α-dicarbonyl compound of the cyclopentanopolyhydrophenanthrene series.
CH234253A (en) Process for the preparation of a sulfonamide compound.
CH239699A (en) Process for the preparation of a salt of a sulfonamide.
CH299273A (en) Process for the production of a thiosemicarbazone.
CH250002A (en) Process for the preparation of a benzenesulfonamide derivative.
CH230433A (en) Process for the preparation of 2 &#39;, 4&#39;-dimethyl-benzoyl-4-amino-benzenesulfonamide.
CH83600A (en) Process for the preparation of 2,4,6,2&#39;-tetraoxybenzophenone (salicylophloroglucine)