CH180882A - Method of creating a therapeutically valuable compound. - Google Patents

Method of creating a therapeutically valuable compound.

Info

Publication number
CH180882A
CH180882A CH180882DA CH180882A CH 180882 A CH180882 A CH 180882A CH 180882D A CH180882D A CH 180882DA CH 180882 A CH180882 A CH 180882A
Authority
CH
Switzerland
Prior art keywords
creating
therapeutically valuable
valuable compound
iodo
disulfonic acid
Prior art date
Application number
Other languages
German (de)
Inventor
Sandoz Chemische Fabri Vormals
Original Assignee
Chem Fab Vormals Sandoz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Fab Vormals Sandoz filed Critical Chem Fab Vormals Sandoz
Publication of CH180882A publication Critical patent/CH180882A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

  

  Verfahren zur Darstellung einer     therapeutiseh    wertvollen Verbindung.    Das vorliegende Verfahren betrifft die       Darstelluug    des     Monoäthanolaminsalzes    der     1-          Jod-8-naphtol-3,6-disulfosäure    und ist dadurch  gekennzeichnet, dass man 1     Mol        1-Jod-8-          naphtol-3,6-disulfosäure    mit 2     Mol        Mono-          ä        thanolamin    umsetzt.  



       Beispiel        .T     11,4 g des     Bariumsalzes    der     1-Jod-8-          naphtol-3,6-disulfosäure    werden in zirka 50 cm'  Wasser, -das 2,8 g     Norioäthariolamin    enthält,  warm gelöst, durch Einleiten von Kohlensäure  das Barium ausgefällt und die Lösung filtriert.  Durch Eindampfen im     Vakuum    bleibt das  Salz als klebrige Masse zurück. Es ist in  Wasser sehr leicht löslich.  



  Die neue Verbindung soll in der Therapie  Verwendung finden.    <I>Beispiel 2</I>  43 g freie reine     1-Jod-8-naphtol-3,6-di-          sulfosäure    werden in zirka 100     cms    Wasser  gelöst, mit 12,2g     Monoäthanolamin    versetzt       und    die neue Verbindung wie im Beispiel 1  beschrieben isoliert.



  Method for the preparation of a therapeutically valuable compound The present process relates to the preparation of the monoethanolamine salt of 1-iodo-8-naphthol-3,6-disulfonic acid and is characterized in that 1 mole of 1-iodo-8-naphthol-3,6-disulfonic acid is mixed with 2 moles of mono-Ä ethanolamine converts.



       Example .T 11.4 g of the barium salt of 1-iodo-8-naphthol-3,6-disulfonic acid are dissolved warm in about 50 cm 'of water containing 2.8 g of norioethariolamine, and the barium is precipitated by introducing carbonic acid and the solution filtered. Evaporation in a vacuum leaves the salt behind as a sticky mass. It is very easily soluble in water.



  The new compound should be used in therapy. <I> Example 2 </I> 43 g of free, pure 1-iodo-8-naphthol-3,6-disulfonic acid are dissolved in about 100 cms of water, mixed with 12.2 g of monoethanolamine and the new compound as in Example 1 described isolated.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung des Morio- äthanolaminsalzes der 1-Jod-8-naphtol-3,6- disulfosäure, dadurch gekennzeichnet, dass man 1 Mol 1-Jod-8-naplitol-3,6-disulfosäure mit 2 Mo1 Monoäthanolamin umsetzt. Die neue Verbindung besteht aus einer klebrigen Masse, welche in Wasser sehr leicht löslich ist. Sie soll in der Therapie Ver wendung finden. PATENT CLAIM: Process for the preparation of the morioethanolamine salt of 1-iodo-8-naphthol-3,6-disulfonic acid, characterized in that 1 mol of 1-iodo-8-naplitol-3,6-disulfonic acid is reacted with 2 mol of monoethanolamine. The new compound consists of a sticky mass which is very easily soluble in water. It should be used in therapy.
CH180882D 1934-06-06 1934-06-06 Method of creating a therapeutically valuable compound. CH180882A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH180882T 1934-06-06
CH175169T 1935-02-15

Publications (1)

Publication Number Publication Date
CH180882A true CH180882A (en) 1935-11-15

Family

ID=25719630

Family Applications (1)

Application Number Title Priority Date Filing Date
CH180882D CH180882A (en) 1934-06-06 1934-06-06 Method of creating a therapeutically valuable compound.

Country Status (1)

Country Link
CH (1) CH180882A (en)

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