CH162587A - Process for the preparation of a complex, therapeutically valuable, organic heavy metal compound. - Google Patents

Process for the preparation of a complex, therapeutically valuable, organic heavy metal compound.

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Publication number
CH162587A
CH162587A CH162587DA CH162587A CH 162587 A CH162587 A CH 162587A CH 162587D A CH162587D A CH 162587DA CH 162587 A CH162587 A CH 162587A
Authority
CH
Switzerland
Prior art keywords
preparation
complex
heavy metal
metal compound
therapeutically valuable
Prior art date
Application number
Other languages
German (de)
Inventor
Sandoz Chemische Fabri Vormals
Original Assignee
Chem Fab Vormals Sandoz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Fab Vormals Sandoz filed Critical Chem Fab Vormals Sandoz
Publication of CH162587A publication Critical patent/CH162587A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer     koniplexen,    therapeutisch wertvollen,     organischeu     t5       Schwermetallverbludnug.       Das vorliegende Verfahren betrifft die  Darstellung von     Chinin-Aritimon-V-gluli:o-          saminat    und     istdadurchgekennzeichnet,        dass          manAntimon-V-glukosamina.t    mit     Chininbase     behandelt.  



  <I>Beispiel:</I>  Eine heisse Lösung von<B>1</B> Teil     Antimon-          V-glukosaminat    in<B>10</B> Teilen Wasser wird  mit einer     methylalkoholischen        Chininlösung     neutralisiert, wobei auf<B>1</B>     Mol        Antimon-V-          glukosaminat   <B>1</B> Äquivalent Chinin verbraucht  wird. Hierauf engt man im Vakuum auf 4  Teile ein und trägt die konzentrierte Lösung  unter Rühren in das     10fache    Volumen Aceton  ein, wobei das     Chinin-Antimon-V-glukosaminat     in weissen Flocken ausfällt.

   Es bildet sich ein    weisses, in Wasser leicht lösliches Pulver  dessen     Antimongehalt        14,1')/o    und dessen       Chiningebalt        18,5'/o    beträgt.



  Process for the representation of a complex, therapeutically valuable, organicu t5 heavy metal bludgeon. The present method relates to the preparation of quinine-aritimony-V-gluli: o-saminate and is characterized by treating antimony-V-glucosamina.t with quinine base.



  <I> Example: </I> A hot solution of <B> 1 </B> part of antimony V-glucosaminate in <B> 10 </B> parts of water is neutralized with a methyl alcoholic quinine solution, with <B> 1 </B> mole of antimony-V-glucosamine <B> 1 </B> equivalent of quinine is consumed. It is then concentrated in vacuo to 4 parts and the concentrated solution is added to 10 times the volume of acetone with stirring, the quinine-antimony-V-glucosaminate precipitating in white flakes.

   A white powder which is easily soluble in water is formed, the antimony content of which is 14.1% and the quinine content 18.5%.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von Chinin- Antimon-V-glukosaminat, dadurch gekenn zeichnet, dass man Antimon-V-glukosaminat mit Chininbase behandelt. Die neue Verbindung stellt in trockenem Zustande ein weisses, in Wasser leicht lös liches Pulver dar mit einem Antimongebalt von 14,1'/o und einem Chiningehalt von<B>18,5</B> 1/o. Die neue Verbindung soll in der Therapie Verwendung finden. PATENT CLAIM: Process for the preparation of quinine-antimony-V-glucosaminate, characterized in that antimony-V-glucosaminate is treated with quinine base. In the dry state, the new compound is a white powder which is easily soluble in water and has an antimony content of 14.1% and a quinine content of 18.5%. The new compound should be used in therapy.
CH162587D 1930-10-10 1931-11-10 Process for the preparation of a complex, therapeutically valuable, organic heavy metal compound. CH162587A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE162587X 1930-10-10

Publications (1)

Publication Number Publication Date
CH162587A true CH162587A (en) 1933-06-30

Family

ID=5682951

Family Applications (1)

Application Number Title Priority Date Filing Date
CH162587D CH162587A (en) 1930-10-10 1931-11-10 Process for the preparation of a complex, therapeutically valuable, organic heavy metal compound.

Country Status (1)

Country Link
CH (1) CH162587A (en)

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