CH140584A - Process for the preparation of a condensation product of the benzodiazine series. - Google Patents

Process for the preparation of a condensation product of the benzodiazine series.

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Publication number
CH140584A
CH140584A CH140584DA CH140584A CH 140584 A CH140584 A CH 140584A CH 140584D A CH140584D A CH 140584DA CH 140584 A CH140584 A CH 140584A
Authority
CH
Switzerland
Prior art keywords
sep
mol
benzodiazine
series
preparation
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH140584A publication Critical patent/CH140584A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Description

  

      Verfahren    zur Darstellung eines Kondensationsproduktes der     Benzodiazinreihe.     
EMI0001.0003     
  
    Gegenstand <SEP> vorliegender <SEP> Erfindung <SEP> ist
<tb>  (-in <SEP> Verfahren <SEP> zur <SEP> Darstellung <SEP> eines <SEP> Kon  dens,atio@nspro,dulzt.es <SEP> der <SEP> Benzodiazinreihe,
<tb>  dadurch <SEP> gekennzeichnet, <SEP> dass <SEP> man <SEP> 1 <SEP> Mol.
<tb>  2. <SEP> 4-I)ihalogenchinazo-l.in <SEP> mit. <SEP> 1 <SEP> Mo.l. <SEP> 1-Amino  8-ox,#napht.a,lin-3. <SEP> 6-.clisulfosäure <SEP> und <SEP> 1 <SEP> M61.
<tb>  4-Amino-4'-o:xya,zobenzol-3'-ca,rbonsäure <SEP> kon  densiert.
<tb>  



  <I>Beispiel:</I>
<tb>  Die <SEP> Lösung <SEP> von <SEP> 19,9 <SEP> Gewichtsteilen <SEP> 2 <SEP> . <SEP> 4  1)ielilo@rcliino-zolin. <SEP> in <SEP> 160 <SEP> Voilumteülen <SEP> Aceton
<tb>  tropft <SEP> man <SEP> bei <SEP> 45-50' <SEP> zu <SEP> einer <SEP> gut <SEP> gerühr  ten <SEP> Lösung <SEP> von, <SEP> 34,1 <SEP> Gewichtsteilen <SEP> 1-Amino <SEP> .
<tb>  8-oxynaplitalin-3 <SEP> . <SEP> 6-disulfosäure <SEP> (saures <SEP> Na  triumsa.lz), <SEP> in <SEP> 600 <SEP> Teilen <SEP> Wasser, <SEP> die <SEP> schwapcli
<tb>  kongosauer <SEP> reagüert. <SEP> Wenn <SEP> sich <SEP> nach <SEP> einiger
<tb>  Zeit <SEP> der <SEP> noch <SEP> ein <SEP> bewegliches <SEP> Chloratom <SEP> ent  haltende <SEP> Zwischenkörper <SEP> a,us <SEP> 1 <SEP> Mol. <SEP> 2. <SEP> 4-Di  ch.l@orchinazoil:

  in <SEP> und> <SEP> 1 <SEP> Moll. <SEP> der <SEP> 1 <SEP> . <SEP> 8-Amino  naplitol-3.6-disulfosäure <SEP> vollständig <SEP> gebildet       hat,     neutrailisiert    man die gelbe Lösung vor  sichtig mit 10     %        iger        Sodal.ösun.g.     



  Inzwischen hat. man 27,8 Gewichtsteile des       Natriumsalzes    der     4-Amino-4'-oxya.zobenzo,l-          3'-carbo,nsäum,        in        700     Wasser       gedöst.    Zu dieser auf<B>70-80'</B>     erhitzten,

      gut       gerührten    Lösung tropft man die neutrale  Lösung des obigen     Zwischenkörpers.    Man  hält noch einige Zeit     bei    dieser     Temperatur.          Wennkeineodernur    noch wenig     Aminoazover-          bindung    durch     Diaxotierprobe    und Giessen in       Soda,lösung        nachweisbar    ist, verdünnt man  mit     etwais    Wasser und     sulzt    aus.

   Das Kon  densationsprodukt     aus    1     Mol.        Dichlürchina.zo-          lin,    1     Moil.        1-Amino-8-o#xyna#phtalin-3.6-di-          sulfos5,ure    und 1     Mol.        4-Amino,-4'-oxyazoben-          zol-3'-carbo#usäure       
EMI0002.0001     
    ist ein     gelbbraunes.        hellles    Pulver, welches in       Warsser    mässig     löslich    ist,

   aber leicht auf Au  satz von etwas Soda mit intensiv     rotstichig          gelber    Farbe in     Läsun-    geht. Die neue Ver  bindung     reagiert    nicht in     salperti.ger        Säure.  



      Process for the preparation of a condensation product of the benzodiazine series.
EMI0001.0003
  
    The subject of <SEP> of the present <SEP> invention <SEP> is
<tb> (-in <SEP> method <SEP> for <SEP> representation <SEP> of a <SEP> condensate, atio @ nspro, dulzt.es <SEP> of the <SEP> benzodiazine series,
<tb> characterized by <SEP>, <SEP> that <SEP> man <SEP> 1 <SEP> Mol.
<tb> 2. <SEP> 4-I) ihalogenchinazo-l.in <SEP> with. <SEP> 1 <SEP> Mo.l. <SEP> 1-amino 8-ox, # napht.a, lin-3. <SEP> 6-.clisulfonic acid <SEP> and <SEP> 1 <SEP> M61.
<tb> 4-Amino-4'-o: xya, zobenzene-3'-ca, rboxylic acid <SEP> condensed.
<tb>



  <I> Example: </I>
<tb> The <SEP> solution <SEP> of <SEP> 19.9 <SEP> parts by weight <SEP> 2 <SEP>. <SEP> 4 1) ielilo @ rcliino-zolin. <SEP> in <SEP> 160 <SEP> volume <SEP> acetone
<tb> <SEP> one <SEP> at <SEP> 45-50 '<SEP> to <SEP> a <SEP> well <SEP> stirred <SEP> solution <SEP> of, <SEP> 34, 1 <SEP> parts by weight <SEP> 1-amino <SEP>.
<tb> 8-oxynaplitalin-3 <SEP>. <SEP> 6-disulfonic acid <SEP> (acidic <SEP> sodium salt), <SEP> in <SEP> 600 <SEP> parts of <SEP> water, <SEP> the <SEP> swabbing
<tb> kongosauer <SEP> reacts. <SEP> If <SEP> <SEP> after <SEP> some
<tb> Time <SEP> the <SEP> nor <SEP> one <SEP> movable <SEP> chlorine atom <SEP> containing <SEP> intermediate bodies <SEP> a, us <SEP> 1 <SEP> mol. <SEP > 2. <SEP> 4-Di ch.l@orchinazoil:

  in <SEP> and> <SEP> 1 <SEP> minor. <SEP> the <SEP> 1 <SEP>. <SEP> 8-amino naplitol-3.6-disulfonic acid <SEP> has completely formed <SEP>, the yellow solution is carefully neutralized with 10% soda solution.



  Meanwhile has. 27.8 parts by weight of the sodium salt of 4-amino-4'-oxya.zobenzo, 1-3'-carbo, nsäum, dozed in 700 water. To this heated to <B> 70-80 '</B>,

      The neutral solution of the above intermediate body is added dropwise to a well-stirred solution. It is kept at this temperature for some time. If no or only a small amount of aminoazo compound can be detected by diaxotizing and pouring in soda solution, dilute with a little water and dissolve.

   The condensation product from 1 mol. Dichlürchina.zo- lin, 1 mol. 1-Amino-8-o # xyna # phtalin-3.6-disulfos5, ure and 1 mol. 4-Amino, -4'-oxyazobenzene-3'-carbo # acid
EMI0002.0001
    is a yellow-brown. light powder, which is moderately soluble in warsser,

   but slightly on top of some soda with an intense reddish yellow color in the lesions. The new compound does not react in nitrous acid.

 

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung eines Non- densationsproduktes der Benzodiazinreihe, EMI0002.0016 dadurch <SEP> gekennzeichnet, <SEP> da.ss <SEP> man <SEP> 1 <SEP> Mol. <tb> 2 <SEP> . <SEP> 4-Dihalogenchinazolin <SEP> mit <SEP> 1 <SEP> Mol. <SEP> 1-Amino 8-o-xyna.phtaJin-8.6-.disulfosäure <SEP> und <SEP> 1 <SEP> Mol. <tb> 4-A;mino-4'-o@xya;zoben.zol-ä@-carbonsäure <SEP> kon densiert. PATENT CLAIM: Process for the preparation of a nondensation product of the benzodiazine series, EMI0002.0016 characterized by <SEP>, <SEP> da.ss <SEP> man <SEP> 1 <SEP> Mol. <tb> 2 <SEP>. <SEP> 4-dihaloquinazoline <SEP> with <SEP> 1 <SEP> mol. <SEP> 1-amino 8-o-xyna.phtaJin-8.6-.disulfonic acid <SEP> and <SEP> 1 <SEP> mol. <tb> 4-A; mino-4'-o @ xya; zoben.zol-ä@-carboxylic acid <SEP> condensed. Das Iioudensatinsprodukt hat die Formel: EMI0002.0018 und stellt ein helles, gelbbraune@.s Pulver dar, das in 'Wasser mässig .löslich ist, auf-: Zusatz von etwas Soda. aber leicht. mit intensiv rot stichig gelber Farbe in Lösung geht. Die neue Verbindung reagiert nicht mit salpetri- ger Säure. .Sie soll ,als Zwischenproidukt für die Herstellung von Farbstoffen Verwendung finden. The ioudensatins product has the formula: EMI0002.0018 and represents a light, yellow-brown powder which is moderately soluble in water. Addition of a little soda. but easy. goes into solution with an intense red, pungent yellow color. The new compound does not react with nitrous acid. . It should be used as an intermediate product for the manufacture of dyes.
CH140584D 1926-12-22 1927-12-14 Process for the preparation of a condensation product of the benzodiazine series. CH140584A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE140584X 1926-12-22
CH133192T 1927-12-12

Publications (1)

Publication Number Publication Date
CH140584A true CH140584A (en) 1930-06-15

Family

ID=25712010

Family Applications (1)

Application Number Title Priority Date Filing Date
CH140584D CH140584A (en) 1926-12-22 1927-12-14 Process for the preparation of a condensation product of the benzodiazine series.

Country Status (1)

Country Link
CH (1) CH140584A (en)

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