CH140593A - Process for the preparation of a condensation product of the benzodiazine series. - Google Patents

Process for the preparation of a condensation product of the benzodiazine series.

Info

Publication number
CH140593A
CH140593A CH140593DA CH140593A CH 140593 A CH140593 A CH 140593A CH 140593D A CH140593D A CH 140593DA CH 140593 A CH140593 A CH 140593A
Authority
CH
Switzerland
Prior art keywords
condensation product
benzodiazine
series
preparation
mol
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH140593A publication Critical patent/CH140593A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

      Verfahren    zur Darstellung eines Kondensationsproduktes der     Benzodiazinreihe.       Gegenstand vorliegender Erfindung ist ein  Verfahren zur Darstellung eines Kondensa  tionsproduktes der     Benzodiazinreihe,    dadurch  gekennzeichnet, dass man 1     Mol        2.4-Dihalo-          genchinazolin    mit 1     Mol        1-Aminobenzol-4-          sulfosäure    und 1     Mol        1-Amino-8-oxynaphtalin-          3.6-disulfosäure    kondensiert.  



  <I>Beispiel:</I>  Man tropft bei<B>50-600</B> zu einer Lösung  von 19,5 Gewichtsteilen 1 -     aminobenzol-4-          sulfosaurem    Natrium in 600 Gewichtsteilen  Wasser, die mit 16,5 Gewichtsteilen Natrium  acetat versetzt wurde, eine Lösung von 19,9  Gewichtsteilen     2,4-Dichlorchinazolin    in der  eben nötigen Menge Aceton langsam zu und  hält die genannte Temperatur ein, bis die  Reaktionskomponenten nicht mehr nachweis  bar sind. Das auf diese Weise hergestellte,         ausgesalzene        Kondensationsprodukt    der For  mel  
EMI0001.0018     
    bildet ein farbloses Pulver, das nicht mit  salpeteriger Säure reagiert.

   Diese Verbindung  teigt man mit Wasser unter Zusatz von  etwas     Dioxan    an und gibt den Teig langsam  zu einer auf<B>90-1000</B> erwärmten Lösung  von 36,3 Gewichtsteilen     1-amino-8-oxynaph-          talin-3.6-disulfosaurem    Natrium in 600 Ge  wichtsteilen Wasser und 30 Teilen Kreide.  Nach Beendigung der Kondensation fällt man  durch Ansäuern.

   Das Kondensationsprodukt  hat die Formel:    
EMI0002.0001     
    Nach der üblichen Aufarbeitung -     Aussalzen     aus einer heissen     sodaalkalischen    Lösung   erhält man sein     Natriumsalz    als ein gelblich  braun gefärbtes, in Blättchen kristallisieren  des, in kaltem Wasser schwer lösliches Pul  ver, welches     auf    Zusatz von Alkali leicht  mit gelber Farbe in Lösung geht.



      Process for the preparation of a condensation product of the benzodiazine series. The present invention is a process for the preparation of a condensation product of the benzodiazine series, characterized in that 1 mole of 2,4-dihalogenquinazoline with 1 mole of 1-aminobenzene-4-sulfonic acid and 1 mole of 1-amino-8-oxynaphthalene-3,6-disulfonic acid condensed.



  <I> Example: </I> It is added dropwise at <B> 50-600 </B> to a solution of 19.5 parts by weight of sodium 1-aminobenzene-4-sulfonic acid in 600 parts by weight of water, which contains 16.5 parts by weight of sodium acetate was added, a solution of 19.9 parts by weight of 2,4-dichloroquinazoline in the just necessary amount of acetone slowly and maintains the temperature mentioned until the reaction components are no longer detectable. The salted out condensation product of the formula prepared in this way
EMI0001.0018
    forms a colorless powder that does not react with nitric acid.

   This compound is made into a paste with water with the addition of a little dioxane and the dough is slowly added to a solution, heated to 90-1000, of 36.3 parts by weight of 1-amino-8-oxynaphthalene-3,6-disulfonic acid Sodium in 600 parts by weight of water and 30 parts of chalk. After the condensation has ended, acidification is used to precipitate.

   The condensation product has the formula:
EMI0002.0001
    After the usual work-up - salting out a hot, soda-alkaline solution, its sodium salt is obtained as a yellowish brown colored, flaky powder, which is sparingly soluble in cold water and which easily dissolves with a yellow color when alkali is added.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung eines Konden sationsproduktes der Benzodiazinreihe, dadurch gekennzeichnet, dass man 1 Mol 2.4-Dihalo- genchinazolin mit 1 Mol 1-Aminobenzol-4- sulfosäure und 11VIo11-Amino-8-oxynaphtalin- 3.6-disulfosäure kondensiert. Der neuen Verbindung kommt als freie Säure die Formel: EMI0002.0015 zu. PATENT CLAIM: Process for the preparation of a condensation product of the benzodiazine series, characterized in that 1 mol of 2,4-dihalogenquinazoline is condensed with 1 mol of 1-aminobenzene-4-sulfonic acid and 11VIo11-amino-8-oxynaphthalene-3.6-disulfonic acid. The new compound has the formula as a free acid: EMI0002.0015 to. Als Natriumsalz stellt sie ein gelblich braunes, in Blättchen kristallisierendes, in kaltem Wasser schwer lösliches Pulver dar, welches 'auf Zusatz von Alkali leicht mit gelber Farbe in Lösung geht. Es soll als Zwischenprodukt für die Herstellung von Farbstoffen und Arzneimitteln dienen. As the sodium salt, it is a yellowish-brown powder which crystallizes in flakes and is sparingly soluble in cold water, which easily dissolves with a yellow color on addition of alkali. It is intended to serve as an intermediate in the manufacture of dyes and drugs.
CH140593D 1926-12-22 1927-12-14 Process for the preparation of a condensation product of the benzodiazine series. CH140593A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE140593X 1926-12-22
CH133192T 1927-12-12

Publications (1)

Publication Number Publication Date
CH140593A true CH140593A (en) 1930-06-15

Family

ID=25712019

Family Applications (1)

Application Number Title Priority Date Filing Date
CH140593D CH140593A (en) 1926-12-22 1927-12-14 Process for the preparation of a condensation product of the benzodiazine series.

Country Status (1)

Country Link
CH (1) CH140593A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1201844B (en) * 1960-05-12 1965-09-30 Mead Johnson & Co Process for the preparation of 4-sulfanilamidoquinazoline derivatives substituted in the 2-position

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1201844B (en) * 1960-05-12 1965-09-30 Mead Johnson & Co Process for the preparation of 4-sulfanilamidoquinazoline derivatives substituted in the 2-position

Similar Documents

Publication Publication Date Title
CH140593A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH312531A (en) Process for making a pyridazone.
CH140590A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH218517A (en) Process for the preparation of 1-methyl-4-phenyl-piperidyl-4-isopropyl-ketone.
AT152741B (en) Process for the preparation of formaldehyde sodium sulfoxylates from arsenobenzene compounds.
AT88646B (en) Process for the production of tanning substances.
AT133505B (en) Process for the preparation of ω-Oxyacylaminobenzolarsin- or -stibinoxden or ω-Oxyacylaminobenzolarsin- or -stibinsäuren.
CH156442A (en) Process for the preparation of a derivative of 3-nitro-4-oxybenzamide.
CH120430A (en) Process for the preparation of a new sulfur- and nitrogen-containing condensation product from the action product of chlorosulfur on a-naphthylamine.
CH140598A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH140586A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH215036A (en) Process for the production of a new condensation product.
CH192066A (en) Process for the preparation of 3-oxy-4- (bis-oxäthyl) -amino-3&#39;-methylamino-4&#39;-oxyarsenobenzene-3&#39;-N-formaldehyde sodium sulfoxylate.
CH140597A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH168923A (en) Process for the preparation of 2-ethylaminobenzene-1-carboxylic acid-4-sulfonic acid.
CH187361A (en) Process for the preparation of N1N2-di- (2-methyl-4-aminoquinolyl-6) -melamine.
CH140297A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH293882A (en) Process for the preparation of a disazo dye.
CH106090A (en) Process for the production of a new intermediate product.
CH205762A (en) Process for the production of a new intermediate product.
CH188983A (en) Process for the preparation of di- (3,4-diaminochinaldyl-6) urea.
CH106105A (en) Process for the production of a new intermediate product.
CH210973A (en) Process for the preparation of a urea derivative.
CH134275A (en) Process for the preparation of a condensation product of the benzodiazine series.
CH140581A (en) Process for the preparation of a condensation product of the benzodiazine series.