CA993878A - Asymmetric synthesis of polycyclic organic compounds - Google Patents

Asymmetric synthesis of polycyclic organic compounds

Info

Publication number
CA993878A
CA993878A CA103,278A CA103278A CA993878A CA 993878 A CA993878 A CA 993878A CA 103278 A CA103278 A CA 103278A CA 993878 A CA993878 A CA 993878A
Authority
CA
Canada
Prior art keywords
organic compounds
asymmetric synthesis
polycyclic organic
polycyclic
asymmetric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA103,278A
Other languages
English (en)
Inventor
Zoltan G. Hajos
David R. Parrish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA993878A publication Critical patent/CA993878A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/73—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catching Or Destruction (AREA)
CA103,278A 1970-01-21 1971-01-21 Asymmetric synthesis of polycyclic organic compounds Expired CA993878A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US476270A 1970-01-21 1970-01-21

Publications (1)

Publication Number Publication Date
CA993878A true CA993878A (en) 1976-07-27

Family

ID=27421984

Family Applications (2)

Application Number Title Priority Date Filing Date
CA103,278A Expired CA993878A (en) 1970-01-21 1971-01-21 Asymmetric synthesis of polycyclic organic compounds
CA247,076A Expired CA1013752A (en) 1970-01-21 1976-03-04 Process for the preparation of cycloalkanediones

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA247,076A Expired CA1013752A (en) 1970-01-21 1976-03-04 Process for the preparation of cycloalkanediones

Country Status (21)

Country Link
US (2) US3975440A (nl)
JP (2) JPS5737573B1 (nl)
AT (4) AT316533B (nl)
BE (1) BE761783A (nl)
CA (2) CA993878A (nl)
CH (3) CH588434A5 (nl)
DE (3) DE2166994C3 (nl)
DK (2) DK146717C (nl)
ES (2) ES387449A1 (nl)
FI (2) FI53450C (nl)
FR (2) FR2077253B1 (nl)
GB (2) GB1325632A (nl)
HU (2) HU166411B (nl)
IE (3) IE35095B1 (nl)
IL (1) IL35985A (nl)
NL (2) NL164267C (nl)
NO (4) NO134983C (nl)
PH (2) PH12661A (nl)
SE (2) SE393798B (nl)
YU (1) YU35332B (nl)
ZA (1) ZA7120B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201869A (en) * 1970-12-21 1980-05-06 Hoffmann-La Roche Inc. Intermediates for steroid total synthesis process utilizing asymmetric induction
ZA814972B (en) * 1980-07-30 1982-07-28 Beecham Group Plc Reduced naphthalenes,their preparation and use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2668858A (en) * 1954-02-09 Process for their preparation
US2407673A (en) * 1941-06-20 1946-09-17 Research Corp Process for the synthesis of 1-keto-8-methylhexahydroindanol-1
US2833694A (en) * 1955-08-25 1958-05-06 Ciba Pharm Prod Inc Process for splitting racemates
NL130309C (nl) * 1963-11-29
NL131552C (nl) * 1965-04-28
AT278767B (de) * 1965-10-13 1970-02-10 Hoffmann La Roche Verfahren zur herstellung von neuen indanderivaten
US3501479A (en) * 1967-05-19 1970-03-17 American Cyanamid Co Dihydroquinolines and substituted dihydroquinolines and method of preparing the same
US3897460A (en) * 1968-10-04 1975-07-29 Hoffmann La Roche 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
DE2016750A1 (de) * 1970-04-04 1971-10-14 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 2,2 disubstituierten Cycloalkan 1,3 dionen

Also Published As

Publication number Publication date
DE2102623A1 (nl) 1971-07-29
IL35985A0 (en) 1971-03-24
CH589024A5 (nl) 1977-06-30
AT348150B (de) 1979-01-25
JPS5373541A (en) 1978-06-30
NL164267C (nl) 1980-12-15
AT316533B (de) 1974-07-10
DK298479A (da) 1979-07-16
YU35332B (en) 1980-12-31
ZA7120B (en) 1971-10-27
ATA392472A (de) 1978-06-15
DK146717B (da) 1983-12-12
IE35093L (en) 1971-07-21
NO134371C (nl) 1976-09-29
DE2166994B2 (de) 1980-01-31
PH11206A (en) 1977-10-28
US3975440A (en) 1976-08-17
NO134983B (nl) 1976-10-11
DE2102623C2 (de) 1982-04-15
NL7907334A (nl) 1980-01-31
PH12661A (en) 1979-07-11
GB1325631A (en) 1973-08-08
DE2166994C3 (de) 1980-10-09
FI53450C (fi) 1978-05-10
US4189447A (en) 1980-02-19
NO134371B (nl) 1976-06-21
FR2112170A1 (nl) 1972-06-16
YU11771A (en) 1980-06-30
IL35985A (en) 1974-05-16
ES387449A1 (es) 1974-12-16
JPS5546377B2 (nl) 1980-11-22
AT315142B (de) 1974-05-10
NL7100813A (nl) 1971-07-23
CH597129A5 (nl) 1978-03-31
IE35095B1 (en) 1975-11-12
HU166411B (nl) 1975-03-28
DE2166994A1 (de) 1977-07-14
NO761104L (nl) 1971-07-22
CH588434A5 (nl) 1977-05-31
NO134983C (nl) 1977-01-26
FR2077253A1 (nl) 1971-10-22
FI771632A (nl) 1977-05-23
SE393798B (sv) 1977-05-23
NL164267B (nl) 1980-07-15
DK146717C (da) 1984-05-21
NO138000C (no) 1978-06-07
GB1325632A (en) 1973-08-08
FR2112170B1 (nl) 1973-06-29
DE2166993A1 (de) 1977-07-14
IE35093B1 (en) 1975-11-12
CA1013752A (en) 1977-07-12
ES394882A1 (es) 1974-03-01
FI53450B (nl) 1978-01-31
AT308087B (de) 1973-06-25
BE761783A (fr) 1971-07-20
NO138000B (no) 1978-02-27
IE35094B1 (en) 1975-11-12
FR2077253B1 (nl) 1973-06-08
JPS5737573B1 (nl) 1982-08-10
SE404607B (sv) 1978-10-16
HU166419B (nl) 1975-03-28

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