NO138000C - Fremgangsmaate for fremstilling av 19-nortestosteron og 19-nor-9beta, 10alfa-testosteron henholdsvis 17beta-tert.-butyleter derav - Google Patents

Fremgangsmaate for fremstilling av 19-nortestosteron og 19-nor-9beta, 10alfa-testosteron henholdsvis 17beta-tert.-butyleter derav

Info

Publication number
NO138000C
NO138000C NO2099/72A NO209972A NO138000C NO 138000 C NO138000 C NO 138000C NO 2099/72 A NO2099/72 A NO 2099/72A NO 209972 A NO209972 A NO 209972A NO 138000 C NO138000 C NO 138000C
Authority
NO
Norway
Prior art keywords
nortestosteron
butyleter
10alfa
9beta
testosteron
Prior art date
Application number
NO2099/72A
Other languages
English (en)
Other versions
NO138000B (no
Inventor
David Richard Parrish
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO138000B publication Critical patent/NO138000B/no
Publication of NO138000C publication Critical patent/NO138000C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/73Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/487Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catching Or Destruction (AREA)
NO2099/72A 1970-01-21 1972-06-13 Fremgangsmaate for fremstilling av 19-nortestosteron og 19-nor-9beta, 10alfa-testosteron henholdsvis 17beta-tert.-butyleter derav NO138000C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US476270A 1970-01-21 1970-01-21

Publications (2)

Publication Number Publication Date
NO138000B NO138000B (no) 1978-02-27
NO138000C true NO138000C (no) 1978-06-07

Family

ID=27421984

Family Applications (4)

Application Number Title Priority Date Filing Date
NO200/71A NO134983C (no) 1970-01-21 1971-01-20
NO2099/72A NO138000C (no) 1970-01-21 1972-06-13 Fremgangsmaate for fremstilling av 19-nortestosteron og 19-nor-9beta, 10alfa-testosteron henholdsvis 17beta-tert.-butyleter derav
NO2098/72A NO134371C (no) 1970-01-21 1972-06-13
NO761104A NO761104L (no) 1970-01-21 1976-03-30

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO200/71A NO134983C (no) 1970-01-21 1971-01-20

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO2098/72A NO134371C (no) 1970-01-21 1972-06-13
NO761104A NO761104L (no) 1970-01-21 1976-03-30

Country Status (21)

Country Link
US (2) US3975440A (no)
JP (2) JPS5737573B1 (no)
AT (4) AT315142B (no)
BE (1) BE761783A (no)
CA (2) CA993878A (no)
CH (3) CH588434A5 (no)
DE (3) DE2102623C2 (no)
DK (2) DK146717C (no)
ES (2) ES387449A1 (no)
FI (2) FI53450C (no)
FR (2) FR2077253B1 (no)
GB (2) GB1325631A (no)
HU (2) HU166411B (no)
IE (3) IE35095B1 (no)
IL (1) IL35985A (no)
NL (2) NL164267C (no)
NO (4) NO134983C (no)
PH (2) PH12661A (no)
SE (2) SE393798B (no)
YU (1) YU35332B (no)
ZA (1) ZA7120B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201869A (en) * 1970-12-21 1980-05-06 Hoffmann-La Roche Inc. Intermediates for steroid total synthesis process utilizing asymmetric induction
ZA814972B (en) * 1980-07-30 1982-07-28 Beecham Group Plc Reduced naphthalenes,their preparation and use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2668858A (en) * 1954-02-09 Process for their preparation
US2407673A (en) * 1941-06-20 1946-09-17 Research Corp Process for the synthesis of 1-keto-8-methylhexahydroindanol-1
US2833694A (en) * 1955-08-25 1958-05-06 Ciba Pharm Prod Inc Process for splitting racemates
NL130309C (no) * 1963-11-29
NL131552C (no) * 1965-04-28
AT278767B (de) * 1965-10-13 1970-02-10 Hoffmann La Roche Verfahren zur herstellung von neuen indanderivaten
US3501479A (en) * 1967-05-19 1970-03-17 American Cyanamid Co Dihydroquinolines and substituted dihydroquinolines and method of preparing the same
US3897460A (en) * 1968-10-04 1975-07-29 Hoffmann La Roche 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
DE2016750A1 (de) * 1970-04-04 1971-10-14 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 2,2 disubstituierten Cycloalkan 1,3 dionen

Also Published As

Publication number Publication date
NO134371C (no) 1976-09-29
IE35094B1 (en) 1975-11-12
DK146717B (da) 1983-12-12
NO134983B (no) 1976-10-11
PH11206A (en) 1977-10-28
AT316533B (de) 1974-07-10
JPS5546377B2 (no) 1980-11-22
DK146717C (da) 1984-05-21
US4189447A (en) 1980-02-19
CA1013752A (en) 1977-07-12
CH597129A5 (no) 1978-03-31
DK298479A (da) 1979-07-16
IL35985A0 (en) 1971-03-24
JPS5737573B1 (no) 1982-08-10
AT348150B (de) 1979-01-25
GB1325632A (en) 1973-08-08
NO138000B (no) 1978-02-27
YU11771A (en) 1980-06-30
PH12661A (en) 1979-07-11
ES394882A1 (es) 1974-03-01
AT315142B (de) 1974-05-10
IE35093B1 (en) 1975-11-12
US3975440A (en) 1976-08-17
NO761104L (no) 1971-07-22
ZA7120B (en) 1971-10-27
HU166419B (no) 1975-03-28
NL7100813A (no) 1971-07-23
FR2077253B1 (no) 1973-06-08
CH588434A5 (no) 1977-05-31
SE404607B (sv) 1978-10-16
ES387449A1 (es) 1974-12-16
FR2077253A1 (no) 1971-10-22
DE2102623C2 (de) 1982-04-15
NL7907334A (nl) 1980-01-31
ATA392472A (de) 1978-06-15
DE2102623A1 (no) 1971-07-29
NL164267C (nl) 1980-12-15
YU35332B (en) 1980-12-31
FI53450C (fi) 1978-05-10
IL35985A (en) 1974-05-16
FR2112170B1 (no) 1973-06-29
DE2166994A1 (de) 1977-07-14
SE393798B (sv) 1977-05-23
NO134983C (no) 1977-01-26
BE761783A (fr) 1971-07-20
NL164267B (nl) 1980-07-15
FI53450B (no) 1978-01-31
CH589024A5 (no) 1977-06-30
AT308087B (de) 1973-06-25
FI771632A (no) 1977-05-23
CA993878A (en) 1976-07-27
IE35093L (en) 1971-07-21
DE2166993A1 (de) 1977-07-14
IE35095B1 (en) 1975-11-12
JPS5373541A (en) 1978-06-30
NO134371B (no) 1976-06-21
GB1325631A (en) 1973-08-08
HU166411B (no) 1975-03-28
DE2166994C3 (de) 1980-10-09
DE2166994B2 (de) 1980-01-31
FR2112170A1 (no) 1972-06-16

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NO138000C (no) Fremgangsmaate for fremstilling av 19-nortestosteron og 19-nor-9beta, 10alfa-testosteron henholdsvis 17beta-tert.-butyleter derav