CA992079A - Optically active 1,4-benzodiazepines and process for the preparation thereof - Google Patents

Optically active 1,4-benzodiazepines and process for the preparation thereof

Info

Publication number
CA992079A
CA992079A CA137,294A CA137294A CA992079A CA 992079 A CA992079 A CA 992079A CA 137294 A CA137294 A CA 137294A CA 992079 A CA992079 A CA 992079A
Authority
CA
Canada
Prior art keywords
benzodiazepines
preparation
optically active
optically
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA137,294A
Other languages
English (en)
Other versions
CA137294S (en
Inventor
Vitomir Sunjic
Nikola Blazevic
Franjo Kajfez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crc Di Ricerca Chimica Sa Cia
Original Assignee
Crc Di Ricerca Chimica Sa Cia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Di Ricerca Chimica Sa Cia filed Critical Crc Di Ricerca Chimica Sa Cia
Priority to CA208,117A priority Critical patent/CA1008468A/en
Application granted granted Critical
Publication of CA992079A publication Critical patent/CA992079A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA137,294A 1971-03-17 1972-03-16 Optically active 1,4-benzodiazepines and process for the preparation thereof Expired CA992079A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA208,117A CA1008468A (en) 1971-03-17 1974-08-29 Optically active 1,4-benzodiazepines and process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH386871A CH554349A (de) 1971-03-17 1971-03-17 Verfahren zur herstellung von optisch aktiven 1,3-dihydro-2h-1,4-benzodiazepin-2-onen.

Publications (1)

Publication Number Publication Date
CA992079A true CA992079A (en) 1976-06-29

Family

ID=4265209

Family Applications (1)

Application Number Title Priority Date Filing Date
CA137,294A Expired CA992079A (en) 1971-03-17 1972-03-16 Optically active 1,4-benzodiazepines and process for the preparation thereof

Country Status (16)

Country Link
AT (1) AT327909B (pt)
BE (1) BE780892A (pt)
CA (1) CA992079A (pt)
CH (1) CH554349A (pt)
DE (1) DE2212526A1 (pt)
ES (1) ES400851A1 (pt)
FR (1) FR2130342B1 (pt)
GB (2) GB1391081A (pt)
HU (1) HU165496B (pt)
IL (2) IL47123A (pt)
NL (1) NL7203536A (pt)
NO (1) NO137896C (pt)
SE (1) SE399887B (pt)
SU (1) SU453842A3 (pt)
YU (1) YU34882B (pt)
ZA (1) ZA721845B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH602672A5 (pt) * 1974-06-28 1978-07-31 Hoffmann La Roche
CH603655A5 (pt) * 1974-10-21 1978-08-31 Hoffmann La Roche
MXPA02001340A (es) * 1999-08-05 2004-07-16 Prescient Neuropharma Inc Compuestos novedosos 1,4-benzodiazepina y derivados de los mismos.

Also Published As

Publication number Publication date
FR2130342B1 (pt) 1977-01-14
IL38991A (en) 1976-09-30
IL47123A (en) 1976-09-30
NO137896B (no) 1978-02-06
NL7203536A (pt) 1972-09-19
BE780892A (fr) 1972-07-17
FR2130342A1 (pt) 1972-11-03
HU165496B (pt) 1974-09-28
CH554349A (de) 1974-09-30
YU69772A (en) 1979-10-31
GB1391081A (en) 1975-04-16
GB1391082A (en) 1975-04-16
IL38991A0 (en) 1972-05-30
ES400851A1 (es) 1975-01-16
YU34882B (en) 1980-04-30
DE2212526A1 (de) 1972-09-21
ZA721845B (en) 1972-12-27
SU453842A3 (pt) 1974-12-15
SE399887B (sv) 1978-03-06
NO137896C (no) 1978-05-16
AT327909B (de) 1976-02-25
ATA214972A (de) 1975-05-15

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