CA991640A - Thiazole derivatives - Google Patents
Thiazole derivativesInfo
- Publication number
- CA991640A CA991640A CA178,970A CA178970A CA991640A CA 991640 A CA991640 A CA 991640A CA 178970 A CA178970 A CA 178970A CA 991640 A CA991640 A CA 991640A
- Authority
- CA
- Canada
- Prior art keywords
- thiazole derivatives
- thiazole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47082574A JPS5238559B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-08-17 | 1972-08-17 | |
| JP48039354A JPS49125359A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-04-05 | 1973-04-05 | |
| ZA00741280A ZA741280B (en) | 1972-08-17 | 1974-02-26 | Thiazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA991640A true CA991640A (en) | 1976-06-22 |
Family
ID=27290112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA178,970A Expired CA991640A (en) | 1972-08-17 | 1973-08-16 | Thiazole derivatives |
Country Status (10)
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001421A (en) * | 1971-10-27 | 1977-01-04 | Syntex (U.S.A.) Inc. | Thiazole cardiovascular agents |
| US4119718A (en) * | 1977-05-02 | 1978-10-10 | Merck & Co., Inc. | 3-Amino-2-oxy-propoxy-substituted isothiazoles |
| US4259341A (en) * | 1977-06-01 | 1981-03-31 | Merck & Co., Inc. | Di- and tri-substituted thiazoles |
| US4260609A (en) * | 1977-06-01 | 1981-04-07 | Merck & Co., Inc. | Di- and tri- substituted thiazoles |
| US4396625A (en) * | 1980-05-13 | 1983-08-02 | Sumitomo Chemical Company, Limited | Treatment of glaucoma or ocular hypertension and ophthalmic composition |
| US4670450A (en) * | 1985-11-13 | 1987-06-02 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic thiazolones |
| HRP20050163A2 (en) | 2002-08-19 | 2005-06-30 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
| AU2004242777B2 (en) * | 2003-05-30 | 2011-05-12 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives and their use as HMG-Co inhibitors |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| AP2007003979A0 (en) * | 2004-11-23 | 2007-06-30 | Warner Lambert Co | 7-(2h-pyrazol-3-yl)-3,5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for thetreatment of lipidemia |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| BRPI0618379A2 (pt) * | 2005-11-08 | 2011-08-30 | Ranbaxy Lab Ltd | processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico |
| WO2007086980A2 (en) * | 2005-11-10 | 2007-08-02 | Duke University | Methods of determining the risk of developing coronary artery disease |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| JP5199885B2 (ja) * | 2006-01-18 | 2013-05-15 | アムジエン・インコーポレーテツド | プロテインキナーゼｂ（ｐｋｂ）阻害剤としてのチアゾール化合物 |
| US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| CL2007000667A1 (es) * | 2006-03-14 | 2008-03-14 | Ranbaxi Lab Ltd | Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e |
| WO2008010087A2 (en) * | 2006-07-14 | 2008-01-24 | Ranbaxy Laboratories Limited | Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof |
| US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| AU2008276512A1 (en) * | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of PKB |
| HK1213886A1 (zh) | 2013-04-17 | 2016-07-15 | 辉瑞大药厂 | 用於治療心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| CN104530033B (zh) * | 2014-12-26 | 2017-07-07 | 江西百神药业股份有限公司 | 一种盐酸阿罗洛尔的制备工艺新方法 |
| CN105646472A (zh) * | 2016-02-29 | 2016-06-08 | 山东齐都药业有限公司 | 一种盐酸阿罗洛尔的制备方法 |
| MX2021008533A (es) | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA599475A (en) * | 1960-06-07 | W. Harman Marion | Aminoethylthiazoles | |
| US2221147A (en) * | 1938-11-18 | 1940-11-12 | Goodrich Co B F | Preparation of aminated esters of sulphydryl compounds |
| US3228952A (en) * | 1962-06-27 | 1966-01-11 | Dow Chemical Co | Thiazole thioethers |
| US3158623A (en) * | 1963-03-01 | 1964-11-24 | Abbott Lab | 5-nitro-2-furylthioamide |
| BE790569A (fr) * | 1971-10-27 | 1973-04-26 | Syntex Corp | Agents cardiovasculaires a base de thiazoles |
-
1973
- 1973-08-14 GB GB3950573A patent/GB1435139A/en not_active Expired
- 1973-08-15 NL NLAANVRAGE7311248,A patent/NL179733C/xx not_active IP Right Cessation
- 1973-08-16 US US05/389,517 patent/US3932400A/en not_active Expired - Lifetime
- 1973-08-16 DK DK452273A patent/DK149893C/da not_active IP Right Cessation
- 1973-08-16 CA CA178,970A patent/CA991640A/en not_active Expired
- 1973-08-16 FR FR7329860A patent/FR2196162B1/fr not_active Expired
- 1973-08-16 CH CH1182373A patent/CH581640A5/xx not_active IP Right Cessation
- 1973-08-16 SE SE7311181A patent/SE421615B/xx unknown
- 1973-08-17 DE DE2341753A patent/DE2341753C2/de not_active Expired
-
1974
- 1974-02-26 ZA ZA00741280A patent/ZA741280B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2196162A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-03-15 |
| DE2341753C2 (de) | 1982-12-09 |
| DK149893C (da) | 1987-04-21 |
| ZA741280B (en) | 1975-03-26 |
| FR2196162B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-01-28 |
| SE421615B (sv) | 1982-01-18 |
| AU5928173A (en) | 1975-02-20 |
| NL179733C (nl) | 1986-11-03 |
| CH581640A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-11-15 |
| GB1435139A (en) | 1976-05-12 |
| NL7311248A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-02-19 |
| DK149893B (da) | 1986-10-20 |
| DE2341753A1 (de) | 1974-02-21 |
| US3932400A (en) | 1976-01-13 |
| NL179733B (nl) | 1986-06-02 |
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