CA971970A - Benzcyclobutene derivatives - Google Patents

Benzcyclobutene derivatives

Info

Publication number
CA971970A
CA971970A CA119,051A CA119051A CA971970A CA 971970 A CA971970 A CA 971970A CA 119051 A CA119051 A CA 119051A CA 971970 A CA971970 A CA 971970A
Authority
CA
Canada
Prior art keywords
benzcyclobutene
derivatives
benzcyclobutene derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA119,051A
Other languages
English (en)
Other versions
CA119051S (en
Inventor
Harm J. Panneman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzona Inc
Original Assignee
Akzona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzona Inc filed Critical Akzona Inc
Application granted granted Critical
Publication of CA971970A publication Critical patent/CA971970A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA119,051A 1970-08-07 1971-07-26 Benzcyclobutene derivatives Expired CA971970A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7011683A NL7011683A (en:Method) 1970-08-07 1970-08-07

Publications (1)

Publication Number Publication Date
CA971970A true CA971970A (en) 1975-07-29

Family

ID=19810731

Family Applications (1)

Application Number Title Priority Date Filing Date
CA119,051A Expired CA971970A (en) 1970-08-07 1971-07-26 Benzcyclobutene derivatives

Country Status (9)

Country Link
US (1) US3804898A (en:Method)
AU (1) AU3153171A (en:Method)
BE (1) BE771055A (en:Method)
CA (1) CA971970A (en:Method)
DE (1) DE2139526A1 (en:Method)
FR (1) FR2102106A1 (en:Method)
HU (1) HU162459B (en:Method)
NL (1) NL7011683A (en:Method)
ZA (1) ZA714729B (en:Method)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013682A (en) * 1973-08-03 1977-03-22 Akzona Incorporated N-hydroxy-amidine compounds
US4101675A (en) * 1973-11-09 1978-07-18 Akzona Incorporated Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method
NL7315350A (nl) * 1973-11-09 1975-05-13 Akzo Nv Nieuwe aminoguanidine verbindingen.
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
US5385946A (en) * 1986-07-10 1995-01-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Method for treating hypertension with disubstituted granidine compounds
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
SG73414A1 (en) 1990-03-02 2000-06-20 Oregon State Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5336689A (en) * 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5574070A (en) * 1990-05-25 1996-11-12 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Substituted guanidines having high binding to the sigma receptor and the use thereof
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
IE920441A1 (en) * 1991-02-08 1992-08-12 Cambridge Neuroscience Res Substituted guanidines and derivatives thereof as modulators¹of neurotransmitter release and novel methodology for¹identifying neurotransmitter release blockers
ES2204920T3 (es) * 1993-05-27 2004-05-01 Cenes Limited Guanidinas substituidas terapeuticas.
KR100424523B1 (ko) * 1993-11-23 2004-09-30 캠브리지 뉴로사이언스, 인코포레이티드 치료용의치환된구아니딘
HU225986B1 (en) * 1994-01-10 2008-02-28 Teva Pharma Use of 1-aminoindan derivatives for preparing pharmaceutical compns. and 1-aminoindan derivatives
US5877218A (en) 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
CA2182302A1 (en) 1994-02-03 1995-08-10 Stanley M. Goldin Therapeutic guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
DE69732984T2 (de) 1996-12-18 2006-02-16 Teva Pharmaceutical Industries Ltd. Aminoindanderivate
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
ES2632638T3 (es) * 2005-12-09 2017-09-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Also Published As

Publication number Publication date
FR2102106A1 (fr) 1972-04-07
AU3153171A (en) 1973-01-25
ZA714729B (en) 1972-04-26
NL7011683A (en:Method) 1972-02-09
DE2139526A1 (en:Method) 1972-03-09
HU162459B (en:Method) 1973-02-28
US3804898A (en) 1974-04-16
BE771055A (nl) 1971-12-16

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