ZA714729B - Novel benzcyclobutene derivatives - Google Patents

Novel benzcyclobutene derivatives

Info

Publication number
ZA714729B
ZA714729B ZA714729A ZA714729A ZA714729B ZA 714729 B ZA714729 B ZA 714729B ZA 714729 A ZA714729 A ZA 714729A ZA 714729 A ZA714729 A ZA 714729A ZA 714729 B ZA714729 B ZA 714729B
Authority
ZA
South Africa
Prior art keywords
benzcyclobutene
derivatives
novel
novel benzcyclobutene
benzcyclobutene derivatives
Prior art date
Application number
ZA714729A
Other languages
English (en)
Inventor
H Panneman
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of ZA714729B publication Critical patent/ZA714729B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06One of the condensed rings being a six-membered aromatic ring the other ring being four-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA714729A 1970-08-07 1971-07-16 Novel benzcyclobutene derivatives ZA714729B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7011683A NL7011683A (xx) 1970-08-07 1970-08-07

Publications (1)

Publication Number Publication Date
ZA714729B true ZA714729B (en) 1972-04-26

Family

ID=19810731

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA714729A ZA714729B (en) 1970-08-07 1971-07-16 Novel benzcyclobutene derivatives

Country Status (9)

Country Link
US (1) US3804898A (xx)
AU (1) AU3153171A (xx)
BE (1) BE771055A (xx)
CA (1) CA971970A (xx)
DE (1) DE2139526A1 (xx)
FR (1) FR2102106A1 (xx)
HU (1) HU162459B (xx)
NL (1) NL7011683A (xx)
ZA (1) ZA714729B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013682A (en) * 1973-08-03 1977-03-22 Akzona Incorporated N-hydroxy-amidine compounds
NL7315350A (nl) * 1973-11-09 1975-05-13 Akzo Nv Nieuwe aminoguanidine verbindingen.
US4101675A (en) * 1973-11-09 1978-07-18 Akzona Incorporated Novel 2,6-di-substituted phenyl-aminoquanidine containing compositions and methods of using same and pharmaceutical compositions containing the same and therapeutic method
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
US5385946A (en) * 1986-07-10 1995-01-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Method for treating hypertension with disubstituted granidine compounds
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
WO1991012797A1 (en) 1990-03-02 1991-09-05 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALF SCIENCES UNIVERSITY Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5336689A (en) * 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5574070A (en) * 1990-05-25 1996-11-12 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Substituted guanidines having high binding to the sigma receptor and the use thereof
DE69230220T2 (de) * 1991-02-08 2000-06-21 Cambridge Neuroscience Res Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
KR20030097618A (ko) * 1993-05-27 2003-12-31 캠브리지 뉴로사이언스, 인코포레이티드 치료용 치환 구아니딘류
JPH09505591A (ja) * 1993-11-23 1997-06-03 ケンブリッジ・ニューロサイエンス・インコーポレーテッド 治療用置換グアニジン類
CA2180841C (en) * 1994-01-10 2007-03-27 Sasson Cohen 1-aminoindan derivatives and compositions thereof
US5914349A (en) 1994-01-10 1999-06-22 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
KR100423272B1 (ko) 1994-02-03 2004-09-01 캠브리지 뉴로사이언스, 인코포레이티드 신경전달물질의방출을조절하는화합물,이의약학적으로허용가능한염및이를포함하는약학조성물
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
DE69738275T2 (de) 1996-12-18 2008-08-28 Teva Pharmaceutical Industries Ltd. Aminoindanderivate
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
BRPI0620659A2 (pt) * 2005-12-09 2017-10-31 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Also Published As

Publication number Publication date
US3804898A (en) 1974-04-16
CA971970A (en) 1975-07-29
NL7011683A (xx) 1972-02-09
AU3153171A (en) 1973-01-25
FR2102106A1 (fr) 1972-04-07
DE2139526A1 (xx) 1972-03-09
HU162459B (xx) 1973-02-28
BE771055A (nl) 1971-12-16

Similar Documents

Publication Publication Date Title
ZA714729B (en) Novel benzcyclobutene derivatives
IE35639B1 (en) Pyridoquinoline derivatives
JPS51526A (en) Okisazoriruukumarin no seizoho
ZA718044B (en) Triazolobenzodiazepine derivatives
ZA717541B (en) Ergolene derivatives
ZA71532B (en) Benzocycloheptaisoquinoline derivatives
PH11791A (en) Triourea derivatives
ZA714137B (en) Indenopyrrole derivatives
HK27776A (en) Diazabicycloundecapentene derivative
YU160871A (en) Lezalnik z leziscem
YU23670A (en) Dusilka z brezvijacno sponko
ZA715596B (en) Triazolobenzodiazepine 5n-oxide derivatives
IL36933A0 (en) 1-phenoxy-3-amino-propan-2-ol derivatives
ZA713111B (en) Substituted carbamoyloxyphenylurea derivatives
ZA716654B (en) Basic thienylalkane derivatives
ZA711487B (en) 2-amino-imidazol-2-ine derivatives
ZA717307B (en) Novel alkyl-steroids
ZA713113B (en) Substituted octahydroquinazoline-diones
MY7600126A (en) Pyridoquinoline derivatives
ZA715776B (en) Leucauramine derivatives
GB1371092A (en) Leucauramine derivatives
PH12699A (en) 5-methyl-n-substituted-morphinan derivatives
ZA707937B (en) Tricarboxystarch derivatives
GB1371091A (en) Leucauramine derivatives
ZA718282B (en) Diaminobenzhydrol derivatives