CA943966A - Acyl xylidide local anaesthetics - Google Patents

Acyl xylidide local anaesthetics

Info

Publication number
CA943966A
CA943966A CA130,662A CA130662A CA943966A CA 943966 A CA943966 A CA 943966A CA 130662 A CA130662 A CA 130662A CA 943966 A CA943966 A CA 943966A
Authority
CA
Canada
Prior art keywords
xylidide
acyl
local anaesthetics
anaesthetics
local
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA130,662A
Other languages
English (en)
Inventor
Bertil H. Takman
Herbert J.F. Adams
George H. Kronberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASTRA PHARMACEUTICAL PRODUCTS
Original Assignee
ASTRA PHARMACEUTICAL PRODUCTS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASTRA PHARMACEUTICAL PRODUCTS filed Critical ASTRA PHARMACEUTICAL PRODUCTS
Application granted granted Critical
Publication of CA943966A publication Critical patent/CA943966A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38Acyl halides
    • C07C53/46Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA130,662A 1970-12-22 1971-12-21 Acyl xylidide local anaesthetics Expired CA943966A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10077770A 1970-12-22 1970-12-22
US00164022A US3812147A (en) 1970-12-22 1971-07-19 Acylxylidide local anaesthetics

Publications (1)

Publication Number Publication Date
CA943966A true CA943966A (en) 1974-03-19

Family

ID=26797539

Family Applications (1)

Application Number Title Priority Date Filing Date
CA130,662A Expired CA943966A (en) 1970-12-22 1971-12-21 Acyl xylidide local anaesthetics

Country Status (23)

Country Link
US (1) US3812147A (forum.php)
JP (1) JPS5644063B1 (forum.php)
AR (1) AR193840A1 (forum.php)
AT (1) AT319205B (forum.php)
AU (1) AU468489B2 (forum.php)
BE (1) BE776656A (forum.php)
BR (1) BR7108466D0 (forum.php)
CA (1) CA943966A (forum.php)
DD (1) DD99779A5 (forum.php)
DE (1) DE2162744C3 (forum.php)
DK (1) DK139814B (forum.php)
ES (2) ES398210A1 (forum.php)
FI (1) FI55027C (forum.php)
FR (1) FR2118985B1 (forum.php)
GB (1) GB1369259A (forum.php)
HU (1) HU163373B (forum.php)
IE (1) IE35909B1 (forum.php)
IT (1) IT1066334B (forum.php)
NL (2) NL172149C (forum.php)
NO (1) NO135934C (forum.php)
PL (1) PL83097B1 (forum.php)
SE (1) SE393374B (forum.php)
SU (1) SU419023A3 (forum.php)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237068A (en) * 1971-07-28 1980-12-02 Astra Pharmaceutical Products, Inc. Primary aminoacylanilides
US3966934A (en) * 1971-12-08 1976-06-29 Astra Pharmaceutical Products, Inc. Synergistic local anesthetic compositions
US3957996A (en) * 1971-12-08 1976-05-18 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic compositions
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (ja) * 1975-08-22 1984-02-23 萬有製薬株式会社 オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ
EP0062322A1 (en) * 1981-04-03 1982-10-13 The B.F. GOODRICH Company Improved process for synthesis of hindered amine stabilizers for polymeric materials
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
SE8900685D0 (sv) * 1989-02-28 1989-02-28 Astra Ab New compounds
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
CN103933572B (zh) 2006-11-20 2017-10-13 哈佛大学校长及研究员协会 治疗疼痛和瘙痒的方法、组合物和试剂盒
CN102725401A (zh) 2009-07-10 2012-10-10 哈佛大学校长及研究员协会 作为抗炎药的永久带电荷的钠和钙通道阻断剂
KR20180069782A (ko) 2015-08-03 2018-06-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 하전 이온 채널 블록커 및 이용 방법
SG11202109713PA (en) 2019-03-11 2021-10-28 Nocion Therapeutics Inc Ester substituted ion channel blockers and methods for use
MA55318A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques chargés et procédés d'utilisation
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
WO2020185928A1 (en) 2019-03-11 2020-09-17 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7628539B2 (ja) 2019-11-06 2025-02-10 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US11332446B2 (en) 2020-03-11 2022-05-17 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124837A (en) * 1966-06-03 1968-08-21 Wyeth John & Brother Ltd Substituted anilides

Also Published As

Publication number Publication date
BR7108466D0 (pt) 1973-06-14
NL7117644A (forum.php) 1972-06-26
SU419023A3 (ru) 1974-03-05
FI55027B (fi) 1979-01-31
IT1066334B (it) 1985-03-04
ES398210A1 (es) 1975-03-16
AT319205B (de) 1974-12-10
GB1369259A (en) 1974-10-23
HU163373B (forum.php) 1973-08-28
IE35909B1 (en) 1976-06-23
AR193840A1 (es) 1973-05-31
BE776656A (fr) 1972-06-14
NL172149B (nl) 1983-02-16
FR2118985B1 (forum.php) 1975-12-26
NO135934B (forum.php) 1977-03-21
AU3709971A (en) 1973-06-28
DE2162744A1 (de) 1972-07-06
IE35909L (en) 1972-06-22
DK139814B (da) 1979-04-23
DE2162744C3 (de) 1982-04-15
NL172149C (nl) 1983-07-18
NL8204126A (nl) 1983-02-01
SE393374B (sv) 1977-05-09
FR2118985A1 (forum.php) 1972-08-04
FI55027C (fi) 1979-05-10
PL83097B1 (forum.php) 1975-12-31
DD99779A5 (forum.php) 1973-08-20
AU468489B2 (en) 1976-01-15
NO135934C (forum.php) 1977-06-29
JPS5644063B1 (forum.php) 1981-10-16
DK139814C (forum.php) 1979-10-01
ES425626A1 (es) 1976-06-16
US3812147A (en) 1974-05-21
DE2162744B2 (de) 1981-07-02

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