CA3251827A1 - ELISA ASSAY FOR BINDING TO A HIGH-SENSITIVITY BIOTINYLED PEPTIDE - Google Patents

ELISA ASSAY FOR BINDING TO A HIGH-SENSITIVITY BIOTINYLED PEPTIDE

Info

Publication number
CA3251827A1
CA3251827A1 CA3251827A CA3251827A CA3251827A1 CA 3251827 A1 CA3251827 A1 CA 3251827A1 CA 3251827 A CA3251827 A CA 3251827A CA 3251827 A CA3251827 A CA 3251827A CA 3251827 A1 CA3251827 A1 CA 3251827A1
Authority
CA
Canada
Prior art keywords
antibody
label
solid support
peptide
biotinylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3251827A
Other languages
English (en)
French (fr)
Inventor
Daria Sizova
Melissa BATONICK
Original Assignee
Alexion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharmaceuticals Inc filed Critical Alexion Pharmaceuticals Inc
Publication of CA3251827A1 publication Critical patent/CA3251827A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
CA3251827A 2022-05-11 2023-05-11 ELISA ASSAY FOR BINDING TO A HIGH-SENSITIVITY BIOTINYLED PEPTIDE Pending CA3251827A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263340766P 2022-05-11 2022-05-11
US63/340,766 2022-05-11
PCT/US2023/021826 WO2023220234A1 (en) 2022-05-11 2023-05-11 High sensitivity biotinylated peptide binding elisa assay

Publications (1)

Publication Number Publication Date
CA3251827A1 true CA3251827A1 (en) 2023-11-16

Family

ID=88730958

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3251827A Pending CA3251827A1 (en) 2022-05-11 2023-05-11 ELISA ASSAY FOR BINDING TO A HIGH-SENSITIVITY BIOTINYLED PEPTIDE

Country Status (6)

Country Link
US (1) US20250298033A1 (https=)
EP (1) EP4522988A1 (https=)
JP (1) JP2025515741A (https=)
CN (1) CN119173764A (https=)
CA (1) CA3251827A1 (https=)
WO (1) WO2023220234A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263078B2 (en) * 2007-09-05 2012-09-11 Inotek Pharmaceuticals Corporation Antibodies against flagellin and uses thereof
MX2011005691A (es) * 2008-11-28 2011-07-20 Univ Emory Metodos para el tratamiento de infecciones y tumores.
US12453778B2 (en) * 2016-09-29 2025-10-28 Ascendis Pharma Bone Diseases A/S Incremental dose finding in controlled-release PTH compounds
CN115298214A (zh) * 2019-11-15 2022-11-04 田纳西大学研究基金会 用于靶向淀粉样蛋白沉积物的经修饰的免疫球蛋白

Also Published As

Publication number Publication date
WO2023220234A1 (en) 2023-11-16
US20250298033A1 (en) 2025-09-25
CN119173764A (zh) 2024-12-20
JP2025515741A (ja) 2025-05-20
EP4522988A1 (en) 2025-03-19

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