JP2025515741A - 高感度ビオチン化ペプチド結合ｅｌｉｓａアッセイ - Google Patents

高感度ビオチン化ペプチド結合ｅｌｉｓａアッセイ Download PDF

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Publication number
JP2025515741A
JP2025515741A JP2024566357A JP2024566357A JP2025515741A JP 2025515741 A JP2025515741 A JP 2025515741A JP 2024566357 A JP2024566357 A JP 2024566357A JP 2024566357 A JP2024566357 A JP 2024566357A JP 2025515741 A JP2025515741 A JP 2025515741A
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JP
Japan
Prior art keywords
antibody
label
solid support
biotinylated
peptide
Prior art date
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Pending
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JP2024566357A
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English (en)
Japanese (ja)
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JP2025515741A5 (https=
Inventor
ダリア シゾヴァ，
メリッサ バトニック，
Original Assignee
アレクシオン ファーマシューティカルズ， インコーポレイテッド
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Application filed by アレクシオン ファーマシューティカルズ， インコーポレイテッド filed Critical アレクシオン ファーマシューティカルズ， インコーポレイテッド
Publication of JP2025515741A publication Critical patent/JP2025515741A/ja
Publication of JP2025515741A5 publication Critical patent/JP2025515741A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
JP2024566357A 2022-05-11 2023-05-11 高感度ビオチン化ペプチド結合ｅｌｉｓａアッセイ Pending JP2025515741A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263340766P 2022-05-11 2022-05-11
US63/340,766 2022-05-11
PCT/US2023/021826 WO2023220234A1 (en) 2022-05-11 2023-05-11 High sensitivity biotinylated peptide binding elisa assay

Publications (2)

Publication Number Publication Date
JP2025515741A true JP2025515741A (ja) 2025-05-20
JP2025515741A5 JP2025515741A5 (https=) 2026-04-14

Family

ID=88730958

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024566357A Pending JP2025515741A (ja) 2022-05-11 2023-05-11 高感度ビオチン化ペプチド結合ｅｌｉｓａアッセイ

Country Status (6)

Country Link
US (1) US20250298033A1 (https=)
EP (1) EP4522988A1 (https=)
JP (1) JP2025515741A (https=)
CN (1) CN119173764A (https=)
CA (1) CA3251827A1 (https=)
WO (1) WO2023220234A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263078B2 (en) * 2007-09-05 2012-09-11 Inotek Pharmaceuticals Corporation Antibodies against flagellin and uses thereof
MX2011005691A (es) * 2008-11-28 2011-07-20 Univ Emory Metodos para el tratamiento de infecciones y tumores.
US12453778B2 (en) * 2016-09-29 2025-10-28 Ascendis Pharma Bone Diseases A/S Incremental dose finding in controlled-release PTH compounds
CN115298214A (zh) * 2019-11-15 2022-11-04 田纳西大学研究基金会 用于靶向淀粉样蛋白沉积物的经修饰的免疫球蛋白

Also Published As

Publication number Publication date
WO2023220234A1 (en) 2023-11-16
CA3251827A1 (en) 2023-11-16
US20250298033A1 (en) 2025-09-25
CN119173764A (zh) 2024-12-20
EP4522988A1 (en) 2025-03-19

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