CA3239503A1 - Rapid t-cell manufacturing - Google Patents

Rapid t-cell manufacturing Download PDF

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Publication number
CA3239503A1
CA3239503A1 CA3239503A CA3239503A CA3239503A1 CA 3239503 A1 CA3239503 A1 CA 3239503A1 CA 3239503 A CA3239503 A CA 3239503A CA 3239503 A CA3239503 A CA 3239503A CA 3239503 A1 CA3239503 A1 CA 3239503A1
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CA
Canada
Prior art keywords
cells
cell
cell population
activator
manufacturing
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Pending
Application number
CA3239503A
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English (en)
French (fr)
Inventor
David Wald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kure Ai Inc
Original Assignee
Kure Ai Inc
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Publication date
Application filed by Kure Ai Inc filed Critical Kure Ai Inc
Publication of CA3239503A1 publication Critical patent/CA3239503A1/en
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2501/50—Cell markers; Cell surface determinants
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
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  • Molecular Biology (AREA)
  • Biophysics (AREA)
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  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3239503A 2021-12-22 2022-12-22 Rapid t-cell manufacturing Pending CA3239503A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163292843P 2021-12-22 2021-12-22
US63/292,843 2021-12-22
PCT/US2022/053815 WO2023122277A2 (en) 2021-12-22 2022-12-22 Rapid t-cell manufacturing

Publications (1)

Publication Number Publication Date
CA3239503A1 true CA3239503A1 (en) 2023-06-29

Family

ID=86903666

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3239503A Pending CA3239503A1 (en) 2021-12-22 2022-12-22 Rapid t-cell manufacturing

Country Status (14)

Country Link
US (1) US20250027042A1 (https=)
EP (2) EP4453188A4 (https=)
JP (2) JP2024546145A (https=)
KR (1) KR20240123837A (https=)
CN (1) CN119698465A (https=)
AR (2) AR128077A1 (https=)
AU (1) AU2022422123A1 (https=)
CA (1) CA3239503A1 (https=)
CL (1) CL2024001919A1 (https=)
CO (1) CO2024008914A2 (https=)
IL (1) IL313516A (https=)
MX (1) MX2024007669A (https=)
UY (1) UY40089A (https=)
WO (2) WO2023122277A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024546145A (ja) * 2021-12-22 2024-12-17 クレ．エーアイ，インク． 迅速ｔ－細胞製造
WO2025083196A1 (en) 2023-10-18 2025-04-24 Tq Therapeutics Gmbh A method of manufacturing a cellular therapy product and respective kits and devices
EP4725578A1 (en) 2024-10-08 2026-04-15 TQ Therapeutics GmbH Column designs for affinity chromatography

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244806A (en) * 1985-08-26 1993-09-14 Eli Lilly And Company DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells
CU24649B1 (es) * 2016-03-19 2023-02-13 Exuma Biotech Corp Retrovirus recombinantes incompetentes de replicación para la transducción de linfocitos y expansión regulada de los mismos
GB201622044D0 (en) * 2016-12-22 2017-02-08 Ucl Business Plc T cell-targeted T cells
CN113840911A (zh) * 2018-09-02 2021-12-24 埃克苏马生物技术公司 用于在血液中或在富集pbmc中基因修饰淋巴细胞的方法和组合物
JP2024546145A (ja) * 2021-12-22 2024-12-17 クレ．エーアイ，インク． 迅速ｔ－細胞製造

Also Published As

Publication number Publication date
AR130098A1 (es) 2024-11-06
WO2024136920A4 (en) 2025-06-12
JP2024546145A (ja) 2024-12-17
UY40089A (es) 2023-07-14
WO2023122277A2 (en) 2023-06-29
KR20240123837A (ko) 2024-08-14
CN119698465A (zh) 2025-03-25
EP4638711A1 (en) 2025-10-29
WO2024136920A1 (en) 2024-06-27
WO2023122277A3 (en) 2023-08-24
JP2026501322A (ja) 2026-01-14
AU2022422123A1 (en) 2024-07-11
EP4453188A4 (en) 2025-12-03
CO2024008914A2 (es) 2024-08-08
EP4453188A2 (en) 2024-10-30
IL313516A (en) 2024-08-01
AR128077A1 (es) 2024-03-20
MX2024007669A (es) 2024-07-09
US20250027042A1 (en) 2025-01-23
CL2024001919A1 (es) 2024-12-06

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